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Li Chen
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Gut Bacteria
Liver-Gut Axis
Bile Diseases
Gene Therapy
Sugar Signaling
Infection
Glycosidase
Functional Genomics
Bacterial Enzymes
Translational Medicine
Areas of Focus
- Exploratory research on the treatment of bile and liver gene diseases using gut bacteria and the liver-gut axis
- Research on sugar signaling and infection using proprietary glycosidase tools
- In-depth research on the functional genomics of bacterial glycosidases
Work Experience
- 1984.09—1989.07 - Fudan University - Faculty Member
- 1992.04—1995.12 - Onyx Pharmaceuticals - Researcher
- 1995.01—1999.08 - University of California, Berkeley - Postdoctoral Researcher
- 1999.09—2004.03 - University of California, Los Angeles (UCLA) - Associate Professor
- 2004.04—2010.08 - GC Corporation, Japan - Senior Scientist/Technical Director
- 2010.09—Present - Fudan University - Distinguished Professor
Academic Background & Achievements
- 1980.09—1984.06 Bachelor's in Microbiology: Fudan University
- 1989.08—1994.12 Ph.D. in Biochemistry: University of Medicine and Dentistry of New Jersey
- 1995.01—1999.08 Postdoctoral Research: University of California, Berkeley
Publications
- Novel NGLY1 gene variants in Chinese children with global developmental delay, microcephaly, hypotonia, hypertransaminasemia, alacrimia, and feeding difficulty, Abuduxikuer Kuerbanjiang, Zou Lin, Wang Lei, Chen Li, Wan JianShe, 2020
- Growth inhibition by bacterial Cas2Em proteins expressed in mammalian cells, Yu X, Wang L, et al., 2020
- Identification and characterization of a novel glycoprotein core xylosidase from the bacterium Elizabethkingia meningoseptica, Hou Linlin, Li Tiansheng, Chen Haiying, Shen Danfeng, Li Mengjie, Guo Yameng, Zou Lin, Wang Lei, Sun Guiqin, Cai Weiming, Ma Jinbiao, Chen Li, 2019
- Filamentation initiated by Cas2 and its association with the acquisition process in cells, Wang Lei, Yu Xin, Li Mengjie, Sun Guiqin, Zou Lin, Li Tiansheng, Hou Linlin, Guo Yameng, Shen Danfeng, Qu Di, Cheng Xunjia, Chen Li, 2019
- Identification and characterization of a core fucosidase from the bacterium Elizabethkingia meningoseptica, Li TianSheng, Li MengJie, Hou LinLin, Guo YaMeng, Wang Lei, Sun Guiqin, Chen Li, 2018
- Identification and characterization of a novel prokaryotic peptide: N-glycosidase from Elizabethkingia meningoseptica, Sun Guiqin, Yu Xiang, Bao Celimuge, Wang Lei, Li Meng, Gan Jianhua, Qu Di, Ma Jinbiao, Chen Li, 2015
Awards
- Golden Pen Award (2021): Seventh Medical Scientist Conference (2022) and Second Physician Career Development Forum
