Professor | Fengfei Ding | Asia Growth Partners

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Name	Fengfei Ding
Contact Information	fengfei_ding@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Fengfei Ding

Contact Information

fengfei_ding@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2004/09-2012/06 Doctor of Medicine: Huazhong University of Science and Technology, Tongji Medical College
Work Experience	2020/01-Present - Fudan University Shanghai Medical College - Junior Researcher 2016/11-2019/12 - Huazhong University of Science and Technology, Tongji Hospital - Resident/Attending Physician in Neurology 2013/01-2016/10 - University of Rochester Medical Center - Postdoctoral Fellow/Assistant Professor in Translational Neurology 2012/07-2012/12 - Huazhong University of Science and Technology, Tongji Hospital - Resident in Neurology
Awards	Shanghai Science and Technology Commission 'Science and Technology Innovation Plan', Rising Star Talent Project (2021/07-2024/06): Role and Mechanism of Astrocytes in Sleep-Wake Regulation China Association for Science and Technology Youth Talent Project (2020/01-2023/01): Chinese Sleep Research Society

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2004/09-2012/06 Doctor of Medicine: Huazhong University of Science and Technology, Tongji Medical College

Work Experience

2020/01-Present - Fudan University Shanghai Medical College - Junior Researcher
2016/11-2019/12 - Huazhong University of Science and Technology, Tongji Hospital - Resident/Attending Physician in Neurology
2013/01-2016/10 - University of Rochester Medical Center - Postdoctoral Fellow/Assistant Professor in Translational Neurology
2012/07-2012/12 - Huazhong University of Science and Technology, Tongji Hospital - Resident in Neurology

Awards

Shanghai Science and Technology Commission 'Science and Technology Innovation Plan', Rising Star Talent Project (2021/07-2024/06): Role and Mechanism of Astrocytes in Sleep-Wake Regulation
China Association for Science and Technology Youth Talent Project (2020/01-2023/01): Chinese Sleep Research Society

Areas of Focus	Mechanisms of Cortical Astrocytes in Sleep-Wake Regulation Role of Deep Brain/Nucleus Astrocytes in Epilepsy, Movement, and Emotion Models Pathophysiological Mechanisms of Chronic Sleep Fragmentation and Its Association with Neurodegenerative Diseases
Publications	Changes in the composition of brain interstitial ions control the sleep-wake cycle, Fengfei Ding, John O’Donnell, Qiwu Xu, Ning Kang, Nanna Goldman, Maiken Nedergaard, 2016 α1-Adrenergic receptors mediate coordinated Ca2+ signaling of cortical astrocytes in awake, behaving mice, Fengfei Ding, John O'Donnell, Alexander S. Thrane, Douglas Zeppenfeld, Hongyi Kang, Lulu Xie, Fushun Wang, Maiken Nedergaard, 2013 Does chronic sleep fragmentation lead to Alzheimer’s disease in young wildtype mice?, Li Ba, Lifang Huang, Ziyu He, Saiyue Deng, Yi Xie, Min Zhang, Cornelius Jacob, Emanuele Antonecchia, Yuqing Liu, Wenchang Xiao, Qingguo Xie, Zhili Huang, Chenju Yi, Nicola D’Ascenzo, Fengfei Ding, 2021 Chronic sleep fragmentation shares similar pathogenesis with neurodegenerative diseases: Endosome-autophagosome-lysosome pathway dysfunction and microglia-mediated neuroinflammation, Yi Xie, Li Ba, Min Wang, Saiyue Deng, Simiao Chen, Lifang Huang, Min Zhang, Wei Wang, Fengfei Ding, 2020 A chronic sleep fragmentation model using vibrating orbital rotor to induce cognitive deficit and anxiety-like behavior in young wild-type mice, Yi Xie, Saiyue Deng, Simiao Chen, Xuejiao Chen, Wenwen Lai, Lifang Huang, Li Ba, Wei Wang, Fengfei Ding, 2020 Inhibition of astrocyte connexin 43 channels facilitates the differentiation of oligodendrocyte precursor cells under hypoxic conditions in vitro, Qiong Wang, Zhen Wang, Yeye Tian, Huaqiu Zhang, Yongkang Fang, Zhiyuan Yu, Wei Wang, Minjie Xie, Fengfei Ding, 2018 Involvement of cationic channels in proliferation and migration of human mesenchymal stem cells, Fengfei Ding, Guibing Zhang, Lu Liu, Lizhong Jiang, Rui Wang, Yunjie Zheng, Guoping Wang, Minjie Xie, Yaqi Duan, 2012 Distinct functional states of astrocytes during sleep and wakefulness: Is norepinephrine the master regulator?, John O’Donnell, Fengfei Ding, Maiken Nedergaard, 2015 Focal solute trapping and global glymphatic impairment in a murine model of multiple microinfarcts, Minghuan Wang, Fengfei Ding, Saiyue Deng, Xuequn Guo, Wei Wang, Jeffrey Iliff, Maiken Nedergaard, 2017 Intersitial ion homeostasis and acid-base balance are maintained in oedematous brain of mice with acute toxic liver failure, Marta Obara-Michlewska, Fengfei Ding, Mariusz Popek, Alexei Verkhratsky, Maiken Nedergaard, Magdalena Zielinska, Jan Albreckt, 2018

Areas of Focus

Mechanisms of Cortical Astrocytes in Sleep-Wake Regulation
Role of Deep Brain/Nucleus Astrocytes in Epilepsy, Movement, and Emotion Models
Pathophysiological Mechanisms of Chronic Sleep Fragmentation and Its Association with Neurodegenerative Diseases

Publications

Changes in the composition of brain interstitial ions control the sleep-wake cycle, Fengfei Ding, John O’Donnell, Qiwu Xu, Ning Kang, Nanna Goldman, Maiken Nedergaard, 2016
α1-Adrenergic receptors mediate coordinated Ca2+ signaling of cortical astrocytes in awake, behaving mice, Fengfei Ding, John O'Donnell, Alexander S. Thrane, Douglas Zeppenfeld, Hongyi Kang, Lulu Xie, Fushun Wang, Maiken Nedergaard, 2013
Does chronic sleep fragmentation lead to Alzheimer’s disease in young wildtype mice?, Li Ba, Lifang Huang, Ziyu He, Saiyue Deng, Yi Xie, Min Zhang, Cornelius Jacob, Emanuele Antonecchia, Yuqing Liu, Wenchang Xiao, Qingguo Xie, Zhili Huang, Chenju Yi, Nicola D’Ascenzo, Fengfei Ding, 2021
Chronic sleep fragmentation shares similar pathogenesis with neurodegenerative diseases: Endosome-autophagosome-lysosome pathway dysfunction and microglia-mediated neuroinflammation, Yi Xie, Li Ba, Min Wang, Saiyue Deng, Simiao Chen, Lifang Huang, Min Zhang, Wei Wang, Fengfei Ding, 2020
A chronic sleep fragmentation model using vibrating orbital rotor to induce cognitive deficit and anxiety-like behavior in young wild-type mice, Yi Xie, Saiyue Deng, Simiao Chen, Xuejiao Chen, Wenwen Lai, Lifang Huang, Li Ba, Wei Wang, Fengfei Ding, 2020
Inhibition of astrocyte connexin 43 channels facilitates the differentiation of oligodendrocyte precursor cells under hypoxic conditions in vitro, Qiong Wang, Zhen Wang, Yeye Tian, Huaqiu Zhang, Yongkang Fang, Zhiyuan Yu, Wei Wang, Minjie Xie, Fengfei Ding, 2018
Involvement of cationic channels in proliferation and migration of human mesenchymal stem cells, Fengfei Ding, Guibing Zhang, Lu Liu, Lizhong Jiang, Rui Wang, Yunjie Zheng, Guoping Wang, Minjie Xie, Yaqi Duan, 2012
Distinct functional states of astrocytes during sleep and wakefulness: Is norepinephrine the master regulator?, John O’Donnell, Fengfei Ding, Maiken Nedergaard, 2015
Focal solute trapping and global glymphatic impairment in a murine model of multiple microinfarcts, Minghuan Wang, Fengfei Ding, Saiyue Deng, Xuequn Guo, Wei Wang, Jeffrey Iliff, Maiken Nedergaard, 2017
Intersitial ion homeostasis and acid-base balance are maintained in oedematous brain of mice with acute toxic liver failure, Marta Obara-Michlewska, Fengfei Ding, Mariusz Popek, Alexei Verkhratsky, Maiken Nedergaard, Magdalena Zielinska, Jan Albreckt, 2018

Astrocytes Sleep-Wake Cycle Cortical Regulation Epilepsy Movement Disorders Emotion Models Chronic Sleep Fragmentation Neurodegenerative Diseases Pathophysiology Brain Mechanisms

Junying Gao - Nanjing Medical University

Renhong Du - Nanjing Medical University

Xin Na - China Medical University

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