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Jianxin Gu
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, Japanese
Glycan Biomarkers
Cancer Diagnosis
Cancer Treatment
O-Glcnac Glycosylation
Functional Mechanisms
Glycan Receptors
Tumor Development
Biomarker Validation
Glycosylation Modification
Cancer Research
Areas of Focus
- Discovery and validation of glycan biomarkers for cancer diagnosis and treatment
- Functional mechanisms of O-GlcNAc glycosylation modification in cancer
- Functional mechanisms of glycan receptors in tumor development
Work Experience
- 1989.3-1989.8 - Osaka University - Postdoctoral Researcher
- 1991.9-1994.4 - Shanghai Medical University (Fudan University Basic Medical College) - Associate Professor of Biochemistry
- 1994.5-present - Shanghai Medical University (Fudan University Basic Medical College) - Professor of Biochemistry
Academic Background & Achievements
- 1983.9-1989.2 Ph.D. in Biochemistry: Nagoya University
- Recognized as an Outstanding Talent by the Ministry of Education
- Named an Excellent Discipline Leader by the Shanghai Science and Technology Commission
- Awarded the title of Shanghai Dawn Scholar
Publications
- Providing Bionic Glycome as internal standards by glycan reducing and isotope labeling for reliable and simple quantitation of N-glycome based on MALDI- MS, Qin W, Zhang Z, Qin R, Han J, Zhao R, Gu Y, Pan Y, Gu J*, Ren S*, 2019
- Fucoidan suppresses the gastric cancer cell malignant phenotype and production of TGF-β1 via CLEC-2, Xu L#, Liu F#, Li C, Li S, Wu H, Guo B, Gu J*, Wang L*, 2020
- Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types, Ren S#, Zhang Z#, Xu C, Guo L, Lu R, Sun Y, Guo J, Qin R, Qin W, Gu J*, 2016
- C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits, Wang L#, Yin J#, Wang X#, Shao M, Duan F, Wu W, Peng P, Jin J, Tang Y, Ruan Y*, Sun Y*, Gu J*, 2016
- Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma, Ruan Y, Sun L, Hao Y, Wang L, Xu J, Zhang W, Xie J, Guo L, Zhou L, Yun X, Zhu H, Shen A, Gu J*, 2012
Awards
- Outstanding Talent by the Ministry of Education
- Excellent Discipline Leader by the Shanghai Science and Technology Commission
- Shanghai Dawn Scholar
