Professor | Jianxin Gu | Asia Growth Partners

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Name	Jianxin Gu
Contact Information	njxgu@shmu.edu.cn
Language ability	Chinese, Japanese
Province	Shanghai

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Name

Jianxin Gu

Contact Information

njxgu@shmu.edu.cn

Language ability

Chinese, Japanese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1983.9-1989.2 Ph.D. in Biochemistry: Nagoya University Recognized as an Outstanding Talent by the Ministry of Education Named an Excellent Discipline Leader by the Shanghai Science and Technology Commission Awarded the title of Shanghai Dawn Scholar
Work Experience	1989.3-1989.8 - Osaka University - Postdoctoral Researcher 1991.9-1994.4 - Shanghai Medical University (Fudan University Basic Medical College) - Associate Professor of Biochemistry 1994.5-present - Shanghai Medical University (Fudan University Basic Medical College) - Professor of Biochemistry
Awards	Outstanding Talent by the Ministry of Education Excellent Discipline Leader by the Shanghai Science and Technology Commission Shanghai Dawn Scholar

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1983.9-1989.2 Ph.D. in Biochemistry: Nagoya University
Recognized as an Outstanding Talent by the Ministry of Education
Named an Excellent Discipline Leader by the Shanghai Science and Technology Commission
Awarded the title of Shanghai Dawn Scholar

Work Experience

1989.3-1989.8 - Osaka University - Postdoctoral Researcher
1991.9-1994.4 - Shanghai Medical University (Fudan University Basic Medical College) - Associate Professor of Biochemistry
1994.5-present - Shanghai Medical University (Fudan University Basic Medical College) - Professor of Biochemistry

Awards

Outstanding Talent by the Ministry of Education
Excellent Discipline Leader by the Shanghai Science and Technology Commission
Shanghai Dawn Scholar

Areas of Focus	Discovery and validation of glycan biomarkers for cancer diagnosis and treatment Functional mechanisms of O-GlcNAc glycosylation modification in cancer Functional mechanisms of glycan receptors in tumor development
Publications	Providing Bionic Glycome as internal standards by glycan reducing and isotope labeling for reliable and simple quantitation of N-glycome based on MALDI- MS, Qin W, Zhang Z, Qin R, Han J, Zhao R, Gu Y, Pan Y, Gu J, Ren S, 2019 Fucoidan suppresses the gastric cancer cell malignant phenotype and production of TGF-β1 via CLEC-2, Xu L#, Liu F#, Li C, Li S, Wu H, Guo B, Gu J, Wang L, 2020 Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types, Ren S#, Zhang Z#, Xu C, Guo L, Lu R, Sun Y, Guo J, Qin R, Qin W, Gu J, 2016 C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits, Wang L#, Yin J#, Wang X#, Shao M, Duan F, Wu W, Peng P, Jin J, Tang Y, Ruan Y, Sun Y, Gu J, 2016 Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma, Ruan Y, Sun L, Hao Y, Wang L, Xu J, Zhang W, Xie J, Guo L, Zhou L, Yun X, Zhu H, Shen A, Gu J*, 2012

Areas of Focus

Discovery and validation of glycan biomarkers for cancer diagnosis and treatment
Functional mechanisms of O-GlcNAc glycosylation modification in cancer
Functional mechanisms of glycan receptors in tumor development

Publications

Providing Bionic Glycome as internal standards by glycan reducing and isotope labeling for reliable and simple quantitation of N-glycome based on MALDI- MS, Qin W, Zhang Z, Qin R, Han J, Zhao R, Gu Y, Pan Y, Gu J*, Ren S*, 2019
Fucoidan suppresses the gastric cancer cell malignant phenotype and production of TGF-β1 via CLEC-2, Xu L#, Liu F#, Li C, Li S, Wu H, Guo B, Gu J*, Wang L*, 2020
Distribution of IgG galactosylation as a promising biomarker for cancer screening in multiple cancer types, Ren S#, Zhang Z#, Xu C, Guo L, Lu R, Sun Y, Guo J, Qin R, Qin W, Gu J*, 2016
C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits, Wang L#, Yin J#, Wang X#, Shao M, Duan F, Wu W, Peng P, Jin J, Tang Y, Ruan Y*, Sun Y*, Gu J*, 2016
Ribosomal RACK1 promotes chemoresistance and growth in human hepatocellular carcinoma, Ruan Y, Sun L, Hao Y, Wang L, Xu J, Zhang W, Xie J, Guo L, Zhou L, Yun X, Zhu H, Shen A, Gu J*, 2012

Glycan Biomarkers Cancer Diagnosis Cancer Treatment O-Glcnac Glycosylation Functional Mechanisms Glycan Receptors Tumor Development Biomarker Validation Glycosylation Modification Cancer Research

Shi Yin - Zhejiang University

Minfeng Shu - Fudan University

Ping Xie - Capital Medical University

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