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Minfeng Shu
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Rna Stability
Malignant Tumors
Innate Immunity
Gene Therapy
Viral Vectors
Cancer Research
Tumor Development
Rna-Binding Proteins
Immunotherapy
Oncology
Areas of Focus
- Research on the role of RNA stability in the development of malignant tumors and innate immunity
- Development of gene therapy drugs for tumors based on viral vectors
Work Experience
- 2011.10—2017.10 - University of Chicago - Postdoctoral Researcher
- 2017.11—Present - Fudan University - Junior Researcher
Academic Background & Achievements
- 2001.09—2006.09 Bachelor's Degree in Clinical Medicine: Wannan Medical College
- 2006.09—2011.07 Ph.D. in Pharmacology: Sun Yat-sen University
Publications
- The role of Activating Transcription Factor 3 in the synthesis of LAT and maintenance of HSV-1 in latent state in ganglia, Minfeng Shu, Te Du, Guoying Zhou and Bernard Roizman, 2015
- Tristetraprolin recruits the herpes simplex virion host shutoff RNase to the A-U rich elements in stress response mRNAs to enable their cleavage, Minfeng Shu, Brunella Taddeo and Bernard Roizman, 2015
- Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein, Minfeng Shu, Brunella Taddeo, Weiran Zhang and Bernard Roizman, 2013
- The nuclear-cytoplasmic shuttling of virion host shutoff RNase is enabled by pUL47 and an embedded nuclear export signal and defines the sites of degradation of AU-rich and stable cellular mRNAs, Minfeng Shu, Brunella Taddeo and Bernard Roizman, 2013
- MicroRNA 335 is required for differentiation of malignant glioma cells induced by activation of cAMP/protein kinase A pathway, Minfeng Shu, Yuehan Zhou, Wenbo Zhu, Haipeng Zhang, Sihan Wu, Jingkao Chen,and Guangmei Yan, 2012
- Targeting oncogenic miR-335 inhibits growth and invasion of malignant astrocytoma cells, Minfeng Shu, Xiaoke Zheng , Sihan Wu, Huimin Lu, Tiandong Leng, Wenbo Zhu, Yuehan Zhou, Yanqiu Ou, Xi Lin, Yuan Lin, Dong Xu, Yuxi Zhou and Guangmei Yan, 2011
- miR-221/222 suppression induced by activation of the cAMP/PKA/CREB1 pathway is required for cAMP-induced bidirectional differentiation of glioma cells, Qian Liu , Ruotong Tian , Panpan Yu and Minfeng Shu, 2021
- Identification and Validation of an Immune-Associated RNA-Binding Proteins Signature to Predict Clinical Outcomes and Therapeutic Responses in Glioma Patients, Ruotong Tian, Yimin Li, Qian Liu and Minfeng Shu, 2021
- Circadian Regulation Patterns With Distinct Immune Landscapes in Gliomas Aid in the Development of a Risk Model to Predict Prognosis and Therapeutic Response, Ruotong Tian, Yimin Li and Minfeng Shu, 2022
- Therapeutic targeting m6A-guided miR-146a-5p signaling contributes to the melittin-induced selective suppression of bladder cancer, Rucheng Yan, Weiwei Dai, Ruixin Wu, Houbao Huang and Minfeng Shu, 2022
Awards
- 2019: Shanghai 'Oriental Scholar' Distinguished Professor, Shanghai Municipal Education Commission
