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Fei Li
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Lung Cancer
Immunotherapy
Targeted Therapy
New Targets
New Strategies
Stem Cells
Tumorigenesis
Spatiotemporal Evolution
Intervention Strategies
Cancer Research
Areas of Focus
- New targets and strategies for lung cancer immunotherapy and targeted therapy
- Spatiotemporal evolution and intervention strategies of stem cell tumorigenesis
Work Experience
- 2021.5-present - Fudan University - Young Researcher, Doctoral Supervisor
- 2017.8-2021.3 - Perlmutter Cancer Center, New York University Medical Center - Postdoctoral Researcher
- 2016.3-2017.7 - Dana-Farber Cancer Institute, Harvard Medical School - Postdoctoral Researcher
- 2015.7-2016.3 - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 2009.9-2015.7 PhD: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
- 2005.9-2009.7 Bachelor: School of Life Sciences, Northeast Normal University
- 2022 National Overseas High-Level Talent Program (Youth)
- 2021 Shanghai Overseas High-Level Talent Program
- 2021 Distinguished Professor of Shanghai Universities (Oriental Scholar)
Publications
- Loss of TSC1/TSC2 sensitizes immune checkpoint blockage in non-small-cell lung cancer, Huang Q*, Li F*#, Hu H*, Fang Z, Gao Z, Xia G, Ng W, Khodadadi-Jamayran A, Chen T, Deng J, Zhang H, Almonte C, Labbe K, Han H, Geng K, Tang S, Freeman G, Li Y, Chen H#, Wong K#, 2022
- Targeting the Atf7ip-Setdb1 complex augments anti-tumor immunity by boosting tumor immunogenicity, Hu H, Khodadadi-Jamayran A, Dolgalev I, Cho H, Badri S, Chiriboga L, Zeck B, Gregorio M, Dowling C, Labbe K, Deng J, Chen T, Zhang H, Zappile P, Chen Z, Ueberheide B, Karatza A, Han H, Ranieri M, Tang S, Jour G, Osman I, Sucker A, Schadendorf D, Tsirigos A, Schalper K, Velcheti V, Huang H, Jin Y, Ji H, Poirier J, Li F#, Wong KK#, 2021
- Epigenetic CRISPR screens identify Npm1 as a therapeutic vulnerability in non-small cell lung cancer, Li F*, Ng W*, Luster T, Hu H, Sviderskiy V, Dowling C, Hollinshead K, Zouitine P, Zhang H, Huang Q, Ranieri M, Wang W, Fang Z, Chen T, Deng J, Zhao K, So H, Khodadadi-Jamayran A, Xu M, Karatza A, Pyon V, Li S, Pan Y, Labbe K, Poirier J, Miller G, Almonte C, Labbe K, Silver H, Rabin A, Jani K, Tsirigos A, Papagiannakopoulos T, Hammerman P, Possemato R, Qi J, Wong KK, 2020
- In vivo epigenetic CRISPR screen identifies Asf1a as an immunotherapeutic target in Kras-mutant lung adenocarcinoma, Li F, Huang Q, Luster T, Hu H, Zhang H, Ng W, Khodadadi-Jamayran A, Wang W, Chen T, Deng J, Ranieri M, Fang Z, Pyon V, Dowling C, Bagdatlioglu E, Almonte C, Labbe K, Silver H, Rabin A, Jani K, Tsirigos A, Papagiannakopoulos T, Hammerman P, Velcheti V, Freeman G, Qi J, Miller G, Wong KK, 2020
- Identification of TRA2B-DNAH5 gene fusion as a novel oncogenic driver in human lung squamous cell carcinoma, Li F*, Fang Z*, Zhang J*, Li Chen, Liu H, Xia J, Zhu H, Guo C, Qin Z, Li FM, Han X, Wang Y, Feng Y, Wang Y, Zhang W, Wang Z, Jin Y, Sun Y, Wei W, Zeng R, Chen H, Ji H, 2016
- LKB1 inactivation elicits a redox imbalance to modulate non-small cell lung cancer plasticity and therapeutic response, Li FM*, Han X*, Li F*, Wang R, Wang H, Gao Y, Wang X, Fang Z, Zhang W, Yao S, Tong X, Wang Y, Feng Y, Sun Y, Li Y, Wong KK, Zhai Q, Chen H, Ji H, 2015
- Identification of RET gene fusion by exon array analyses in 'pan-negative' lung adenocarcinomas from never smokers, Li F*, Feng Y*, Fang R*, Fang Z, Xia J, Han X, Liu XY, Chen H, Liu H, Ji H, 2012
Awards
- 2022: Excellent Award at the Oriental Forum
- 2015: Outstanding Graduate of Beijing Universities
- 2015: Outstanding Graduate of the University of Chinese Academy of Sciences
- 2014: National Scholarship
- 2014: Model Student of the University of Chinese Academy of Sciences
- 2014: Wang Yinglai Scholarship
- 2012: Pfizer Scholarship
- 2009: Outstanding Graduate of Northeast Normal University
