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Jing Liu
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Hbv
Molecular Biology
Virology
Immunology
Animal Models
Drug Development
Recombinant Vectors
Bioinformatics
Ancient Viruses
Liver Cancer
Areas of Focus
- Molecular Biology of Hepatitis B Virus (HBV)
- Molecular Virology
- Immunology
- HBV Animal Models and Drug Development
- Recombinant HBV Vector Systems and Applications
- Viral Bioinformatics
- Ancient and Emerging Viruses
- Regulation of Liver Gene Expression
- Mechanisms of Liver Cancer and Other Tumors
- Drug Research
Work Experience
- 2002.04—2007.09 Assistant Researcher - Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
- 2007.09—2014.12 Assistant Researcher - Institute of Biomedical Sciences/School of Basic Medical Sciences, Fudan University
- 2014.12—Present Associate Professor - Institute of Biomedical Sciences/School of Basic Medical Sciences, Fudan University
Academic Background & Achievements
- 1992.09—1996.06 Bachelor's in Molecular Biology: Nankai University
- 1996.09—2002.04 Ph.D. in Biochemistry and Molecular Biology: Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences
Publications
- High mobility group AT-hook 1 (HMGA1) is an important positive regulator of hepatitis B virus (HBV) that is reciprocally upregulated by HBV X protein., Shen, Z., Wu, J., Gao, Z., Zhang, S., Chen, J., He, J., Guo, Y., Deng, Q., Xie, Y., Liu, J., Zhang, J., 2022
- Characterization of IL-21-expressing recombinant hepatitis B virus (HBV) as a therapeutic agent targeting persisting HBV infection., Shen, Z., Wu, J., Gao, Z., Wang, J., Zhu, H., Mao, R., Wang, X., Zhang, J., Xie, Y., Liu, J., 2020
- Restriction of exogenous DNA expression by SAMHD1., Gu, C., Ming, L., Fang, Y., Liu, X., Zhang, J., Zelinskyy, G., Deng, Q., Liu, J., Xie, Y., 2020
- IL-21-based therapies induce clearance of hepatitis B virus persistence in mouse models., Shen, Z., Liu, J., Wu, J., Zhu, Y., Li, G., Wang, J., Luo, M., Deng, Q., Zhang, J., Xie, Y., 2019
- Hepatitis B virus persistence in mice reveals IL-21 and IL-33 as regulators of viral clearance., Shen, Z., Yang, H., Yang, S., Wang, W., Cui, X., Zhou, X., Liu, W., Pan, S., Liu, Y., Zhang, J., Zhang, J., Xie, Y., Liu, J., 2017
- Prospero-related homeobox 1 drives angiogenesis of hepatocellular carcinoma through selectively activating IL-8 expression., Liu, Y., Zhang, Y., Wang, S., Dong, Q. Z., Shen, Z., Wang, W., Tao, S., Gu, C., Liu, J., Xie, Y., Qin, L. X., 2017
- Association of Mutations in Toll-like Receptor 2 Signaling Genes With Fulminant Form of Hepatitis B-Related Acute Liver Failure., Han, Y., Gu, L., Liu, J., Li, X., Wang, M., Gong, Q., Yu, D., Yang, Z., Zhang, D., Yang, H., Shen, Z., Zhu, H., Xie, Y., Zhang, X., 2017
- Re-Designed Recombinant Hepatitis B Virus Vectors Enable Efficient Delivery of Versatile Cargo Genes to Hepatocytes with Improved Safety., Bai, W., Cui, X., Chen, R., Tao, S., Hong, R., Zhang, J., Zhang, J., Wang, Y., Xie, Y., Liu, J., 2016
- PROX1 promotes hepatocellular carcinoma proliferation and sorafenib resistance by enhancing beta-catenin expression and nuclear translocation., Liu, Y., Ye, X., Zhang, J.B., Ouyang, H., Shen, Z., Wu, Y., Wang, W., Wu, J., Tao, S., Yang, X., Qiao, K., Zhang, J., Liu, J., Fu, Q., Xie, Y., 2015
- Quantitative Proteomic Analysis of Exosome Protein Content Changes Induced by Hepatitis B Virus in Huh-7 Cells Using SILAC Labeling and LC-MS/MS., Zhao, X., Wu, Y., Duan, J., Ma, Y., Shen, Z., Wei, L., Cui, X., Zhang, J., Xie, Y., Liu, J., 2014
