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Chao Lu
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Circadian Rhythms
Cellular Metabolism
Molecular Mechanisms
Circadian Genes
Disease Pathogenesis
Clock Protein
Slc25A10
Mitochondrial Metabolism
Bnip3
Mitophagy
Areas of Focus
- Circadian rhythms and cellular metabolism
- Molecular mechanisms of circadian genes in disease pathogenesis
Work Experience
- 1999.07 - 2006.06 Fudan University Shanghai Medical College, Department of Physiology and Pathophysiology - Teaching Assistant
- 2006.07 - 2016.12 Fudan University Shanghai Medical College, Department of Physiology and Pathophysiology - Lecturer
- 2016.12 - Present Fudan University Shanghai Medical College, Department of Physiology and Pathophysiology - Associate Professor
Academic Background & Achievements
- 1994.09 - 1999.07 Bachelor's in Clinical Medicine: Shanghai Tiedao University Medical School
- 2000.09 - 2004.07 Master's in Pathophysiology: Fudan University
- 2006.09 - 2010.07 PhD in Pathophysiology: Fudan University
- 2011.02 - 2014.03 Visiting Scholar: Johns Hopkins University School of Medicine
Publications
- CLOCK regulates Drp1 mRNA stability and mitochondrial homeostasis by interacting with PUF60, Lirong Xu, Jiaxin Lin, Yutong Liu, Bingxuan Hua, Qianyun Cheng, Changpo Lin, Zuoqin Yan, Yaping Wang, Ning Sun, Ruizhe Qian, Chao Lu, 2022
- BMAL1 regulates mitochondrial fission and mitophagy through mitochondrial protein BNIP3 and is critical in the development of dilated cardiomyopathy, Ermin Li, Xiuya Li, Jie Huang, Chen Xu, Qianqian Liang, Kehan Ren, Aobing Bai, Chao Lu, Ruizhe Qian, Ning Sun, 2020
- The circadian protein CLOCK regulates cell metabolism via the mitochondrial carrier SLC25A10, Tingting Cai, Bingxuan Hua, Dawei Luo, Lirong Xu, Qianyun Cheng, Gongsheng Yuan, Zuoqin Yan, Ning Sun, Luchun Hua, Chao Lu, 2019
- Clock mutant promotes osteoarthritis by inhibiting the acetylation of NF kappa B, Gongsheng Yuan, Lirong Xu, Tingting Cai, Bingxuan Hua, Ning Sun, Zuoqin Yan, Chao Lu, Qian Ruizhe, 2019
- Clock represses preadipocytes adipogenesis via GILZ, Zhu Zhu, Lirong Xu, Tingting Cai, Gongsheng Yuan, Ning Sun, Chao Lu, Qian Ruizhe, 2018
- Clock mediates liver senescence by controlling ER stress, Gongsheng Yuan, Bingxuan Hua, Ermin Li, Lirong Xu, Tingting Cai, Yiqing Huang, Ning Sun, Zuoqin Yan, Chao Lu, Qian Ruizhe, 2017
- The circadian gene Clock regulates bone formation via PDIA3, Gongsheng Yuan, Bingxuan Hua, Yang Yang, Lirong Xu, Tingting Cai, Ning Sun, Zuoqin Yan, Chao Lu, Qian Ruizhe, 2017
- Role of circadian gene Clock during differentiation of mouse pluripotent stem cells, Chao Lu, Yang Yang, Ran Zhao, Bingxuan Hua, Chen Xu, Zuoqin Yan, Ning Sun, Ruizhe Qian, 2016
- An Autoregulatory Mechanism Imposes Allosteric Control on the V(D)J Recombinase by Histone H3 Methylation, Chao Lu, Ward A, Bettridge J, Liu Y, Desiderio S, 2015
