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Xiuping Liu
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, English
Oncogenes
Non-Coding Rnas
Breast Cancer
Multidrug Resistance
Invasion
Metastasis
Molecular Mechanisms
Hscs
Quiescence
Activation
Areas of Focus
- Role and molecular mechanisms of oncogenes and non-coding RNAs in breast cancer multidrug resistance and invasion/metastasis
- Identification of target genes and post-translationally modified proteins in the transition of HSCs from quiescence to activation, providing strategies for the treatment and reversal of liver fibrosis
Work Experience
- 2020-present - Chinese Medical Association Pathology Branch - Member
- 2018-present - Chinese Medical Association Pathology Branch Autopsy Working Committee - Deputy Leader
- 2020-present - Chinese Medical Association Pathology Branch Digestive Group - Member
- 2019-present - Shanghai Medical Association Pathology Special Committee - Deputy Director
- 2019-present - Shanghai Medical Association Pathology Special Committee Molecular Pathology Group - Leader
- 2015-present - Shanghai Medical Association Medical Appraisal Expert
- 2014-present - Editorial Board Member of 'Chinese Journal of Pathology'
- 2016-present - Editorial Board Member of 'Journal of Diagnostic Pathology'
- 2018-present - Editorial Board Member of 'Journal of Gastroenterology and Hepatology'
- 2018-present - Member of the Graduate Committee, School of Basic Medical Sciences
- 2018-present - Member of the Undergraduate Committee, School of Basic Medical Sciences
Academic Background & Achievements
- Contributed to the 9th edition of the national unified 'Pathology' textbook
- Contributed to the national undergraduate English 'Pathology' textbook
- Contributed to the national graduate course textbook 'Principles and Choices of Medical Experimental Technology'
- Contributed to the national graduate course textbook 'Molecular Pathology'
Publications
- RACGAP1 modulates ECT2-Dependent mitochondrial quality control to drive breast cancer metastasis., Xiuping Liu, 2021
- Long non-coding RNA RACGAP1P promotes breast cancer invasion and metastasis via miR-345-5p/RACGAP1-mediated mitochondrial fission., Xiuping Liu, 2020
- Extracellular 5'-nucleotidase (CD73) promotes human breast cancer cells growth through AKT/GSK-3β/β-catenin/cyclinD1 signaling pathway., Xiuping Liu, 2018
- Trichostatin A inhibits the activation of Hepatic stellate cells by Increasing C/EBP-α Acetylation in vivo and in vitro., Xiuping Liu, 2018
- Activation of pluripotent genes in hepatic progenitor cells in the transition of nonalcoholic steatohepatitis to pre-malignant lesions., Xiuping Liu, 2017
- Rab14 suppression mediated by miR-320a promotes cell proliferation and invasion/metastasis in human breast cancer., Xiuping Liu, 2016
- C/EBP-α ameliorates CCl4-induced liver fibrosis in mice through promoting apoptosis of hepatic stellate cells with little apoptotic effect on hepatocytes in vitro and in vivo., Xiuping Liu, 2012
- Involvement of NF-kappaB/miR-448 regulatory feedback loop in chemotherapy-induced epithelial-mesenchymal transition of breast cancer cells., Xiuping Liu, 2011
- RACK1 promotes breast carcinoma proliferation and invasion/metastasis in vitro and in vivo., Xiuping Liu, 2010
- Twist1 Mediated Adriamycin-induced Epithelial-Mesenchymal Transition (EMT) Relates to Multidrug Resistance and Invasive Potential in Breast Cancer Cells., Xiuping Liu, 2009
Awards
- Shanghai Science and Technology Award (Third Prize) (2013)
- Shanghai Talent Award (2012)
- Fudan University March 8th Red Banner Holder (2009-2010)
- Fudan University Model Couple (2014-2015)
- School of Basic Medical Sciences 'Excellent Undergraduate Professional Tutor' (2014)
