Feifei Wang

ffwang@fudan.edu.cn

Chinese, English

Shanghai

Fudan University

Basic Medical Sciences

• 1999.09—2003.06 Bachelor: Fudan University, School of Life Sciences
• 2005.09—2010.07 PhD: Fudan University, School of Basic Medical Sciences, Pharmacology

• 2017.12—Present - Fudan University, School of Basic Medical Sciences - Professor
• 2012.12—2017.12 - Fudan University, School of Basic Medical Sciences - Associate Professor
• 2008.07—2012.12 - Fudan University, School of Basic Medical Sciences - Lecturer
• 2014.04—2015.10 - University of Wisconsin-Madison - Postdoctoral Researcher

• 2011: First Prize in Natural Science by the Ministry of Education for new mechanisms of opioid receptor signal transduction (Fourth Contributor)
• 2013: Second Prize in Natural Science by the Ministry of Education for research on new mechanisms of neural plasticity regulation (Third Contributor)

Neural plasticity mechanisms of reward and stress: The expression and function of genes in the brain are crucial for the normal physiological function of neurons. Abnormal gene expression and function are the pathological basis for the development of neurological diseases. The research group focuses on the neural signaling network and gene expression regulation in the brain, analyzing the cellular and molecular basis of neural circuit remodeling in relevant brain regions due to addictive drugs and stress stimuli, providing potential biological targets for intervening in brain diseases related to pathological memory and emotional disorders.

• CRHCeA→VTA inputs inhibit the positive ensembles to induce negative affect of opiate withdrawal, Jiang C#, Yang X#, He G#, Wang F, Xu W, Mao Y, and Ma L*, Wang F*, 2021
• O-GlcNAcylation in ventral tegmental area dopaminergic neurons regulates the response to natural reward and motor learning ability, Shao M#, Yang X#, Zhang C, Jiang C, Ma L*, Wang F*, 2021
• Morphine coordinates SST and PV interneurons in the prelimbic cortex to disinhibit pyramidal neurons and enhance reward, Jiang C, Wang X, Le Q, Liu P, Liu C, Wang Z, He G, Zheng P, Wang F*, Ma L*, 2021
• Dorsal hippocampus- and ACC-projecting medial septum neurons differentially contribute to the recollection of episodic-like memory, Jin T, Chen R, Shao M, Yang X, Ma L, Wang F*, 2020
• Retrieval-driven hippocampal Nptx2 Plasticity Facilitates the Extinction of Cocaine-Associated Context Memory, Wang Z#, Jin T#, Le Q#, Liu C, Wang X, Wang F*, Ma L*, 2020
• Retrieval-induced Upregulation of Tet3 in Pyramidal Neurons of the Dorsal Hippocampus Mediates Cocaine-Associated Memory Reconsolidation, Liu C, Sun X, Wang Z, Le Q, Liu P, Jiang C, Wang F*, Ma L*, 2018
• GRK5 regulates social behaviour via suppression of mTORC1 signaling in medial prefrontal cortex, Niu B#, Liu P#, Shen M#, Liu C, Wang L, Wang F* and Ma L*, 2018
• Integrative Single-Cell Transcriptomics Reveals Molecular Networks Defining Neuronal Maturation during Adult Neurogenesis, Gao Y#, Wang F#, Brian E. Eisinger#, Laurel E. Kelnhofer1, Emily Jobe and Zhao X*, 2017
• Mesolimbic leptin signaling negatively regulates cocaine conditioned reward, Shen M, Jiang C, Liu P, Wang F*, Ma L*, 2016
• Positive feedback between RNA-binding protein HuD and transcription factor SATB1 promotes neurogenesis, Wang F, Tidei J, Polich E, Gao Y, Zhao H, Perrone-Bizzozero N*, Guo W*, Zhao X*, 2015