Professor | Bin Wang | Asia Growth Partners

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Name	Bin Wang
Contact Information	bwang3@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Bin Wang

Contact Information

bwang3@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	1978-1982 Bachelor's in Biology: Shandong University 1984-1989 Ph.D. in Medicine: University of Cincinnati College of Medicine 1989-1992 Postdoctoral Research: Wistar Institute
Work Experience	1982-1984 - Chinese Academy of Sciences, Institute of Zoology - Assistant Researcher 1992-1994 - University of Pennsylvania School of Medicine - Instructor 1993-1998 - Apollon Inc. - Scientific Advisor 1995-1998 - University of Pennsylvania School of Medicine, Department of Pathology - Assistant Professor 2001-2002 - Xinjiang University, School of Life Sciences and Technology - Distinguished Professor 2003-2010 - China Agricultural University - Distinguished Professor 2010-Present - Fudan University, School of Basic Medical Sciences - Distinguished Professor 2016-2020 - Director, National Engineering Laboratory for Therapeutic Vaccines 2021-Present - Director, Fudan Vaccine Research and Translational Enterprise Joint Laboratory
Awards	National Science and Technology Plan Outstanding Team Award (11th Five-Year Plan) Shanghai Patent Invention Gold Award (2015) Scientific Chinese Person of the Year (2015) Shanghai Patent Invention Gold Award (2018)

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

1978-1982 Bachelor's in Biology: Shandong University
1984-1989 Ph.D. in Medicine: University of Cincinnati College of Medicine
1989-1992 Postdoctoral Research: Wistar Institute

Work Experience

1982-1984 - Chinese Academy of Sciences, Institute of Zoology - Assistant Researcher
1992-1994 - University of Pennsylvania School of Medicine - Instructor
1993-1998 - Apollon Inc. - Scientific Advisor
1995-1998 - University of Pennsylvania School of Medicine, Department of Pathology - Assistant Professor
2001-2002 - Xinjiang University, School of Life Sciences and Technology - Distinguished Professor
2003-2010 - China Agricultural University - Distinguished Professor
2010-Present - Fudan University, School of Basic Medical Sciences - Distinguished Professor
2016-2020 - Director, National Engineering Laboratory for Therapeutic Vaccines
2021-Present - Director, Fudan Vaccine Research and Translational Enterprise Joint Laboratory

Awards

National Science and Technology Plan Outstanding Team Award (11th Five-Year Plan)
Shanghai Patent Invention Gold Award (2015)
Scientific Chinese Person of the Year (2015)
Shanghai Patent Invention Gold Award (2018)

Areas of Focus	Research on new therapeutic and tolerogenic vaccines Research on new vaccine adjuvants Clinical immunology testing and new biomarkers Mechanisms of immune tolerance and virus-host immune regulation
Publications	Identification of a promiscuous conserved CTL epitope within the SARS-CoV-2 spike protein, Sheng Jiang, Shuting Wu, Gan Zhao, Yue He, Xinrong Guo, Zhiyu Zhang, Jiawang Hou, Yuan Ding, Alex Cheng & Bin Wang, 2022 Comparison of Wild Type DNA Sequence of Spike Protein from SARS-CoV-2 with Optimized Sequence on The Induction of Protective Responses Against SARS-Cov-2 Challenge in Mouse Model, Sheng Jiang, Shuting Wu, Gan Zhao, Yue He, Linlin Bao, Jiangning Liu, Chuan Qin, Jiawang Hou, Yuan Ding, Alex Cheng, Brian Jiang, John Wu, Jian Yan, Laurent Humeau, Ami Patella, David B. Weiner, Kate Broderick & Bin Wang, 2021 Development of A Therapeutic Vaccine Targeting Merkel Cell Polyomavirus Capsid Protein VP1 against Merkel cell carcinoma, Dan Xu, Sheng Jiang, Yue He, Xiang Jin, Gan Zhao, and Bin Wang, 2021 Precise spatio-temporal interruption of regulatory T cell-mediated CD8+ T cell suppression leads to tumor immunity, Xiaoyu Zhou, Shushu Zhao, Yue He, Shuang Geng, Yan Shi, and Bin Wang, 2019 Hepatitis B e antigen induces the expansion of monocytic myeloid-derived suppressor cells to dampen T-cell function in chronic hepatitis B virus infection, Feifei Yang, Xueping Yu, Chenliang Zhou, Richeng Mao, Mengqi Zhu, Haoxiang Zhu, Zhenxuan Ma, Bidisha Mitra, Gan Zhao, Yuxian Huang, Haitao Guo, Bin Wang, Jiming Zhang, 2019 Microneedles Improve The Immunogenicity Of DNA Vaccines, Shijie Zhang, Shushu Zhao, Xiang Jin, Bin Wang and Gan Zhao, 2018 Critical role of regulatory T cells in the latency and stress-induced reactivation of HSV-1, Wencong Yu, Shuang Geng, Yuanzhen Suo, Xunbin Wei, Qiliang Cai, Bing Wu, Xian Zhou, Yan Shi and Bin Wang, 2018 Revisiting GM-CSF as an adjuvant for therapeutic vaccines, Weidong Zhao, Gan Zhao, and Bin Wang, 2017 Biomarkers Distinguish HBeAg Seroconverted from Non-Converted Individuals in Chronic Hepatitis B Patients Treated with a Therapeutic Vaccine, Xian Zhou, Shuang Geng, Shijie Zhang, Weidong Zhao, Yumei Wen, Xuanyi Wang and Bin Wang, 2017 Induced regulatory T cells superimpose their suppressive capacity with effector T cells in lymph nodes via antigen-specific S1p1-dependent egress blockage, Shuang Geng, Yiwei Zhong, Xiaoyu Zhou, Gan Zhao, Xiaoping Xie, Yechun Pei, Hu Liu, Huiyuan Zhang, Yan Shi and Bin Wang, 2017

Areas of Focus

Research on new therapeutic and tolerogenic vaccines
Research on new vaccine adjuvants
Clinical immunology testing and new biomarkers
Mechanisms of immune tolerance and virus-host immune regulation

Publications

Identification of a promiscuous conserved CTL epitope within the SARS-CoV-2 spike protein, Sheng Jiang, Shuting Wu, Gan Zhao, Yue He, Xinrong Guo, Zhiyu Zhang, Jiawang Hou, Yuan Ding, Alex Cheng & Bin Wang, 2022
Comparison of Wild Type DNA Sequence of Spike Protein from SARS-CoV-2 with Optimized Sequence on The Induction of Protective Responses Against SARS-Cov-2 Challenge in Mouse Model, Sheng Jiang, Shuting Wu, Gan Zhao, Yue He, Linlin Bao, Jiangning Liu, Chuan Qin, Jiawang Hou, Yuan Ding, Alex Cheng, Brian Jiang, John Wu, Jian Yan, Laurent Humeau, Ami Patella, David B. Weiner, Kate Broderick & Bin Wang, 2021
Development of A Therapeutic Vaccine Targeting Merkel Cell Polyomavirus Capsid Protein VP1 against Merkel cell carcinoma, Dan Xu, Sheng Jiang, Yue He, Xiang Jin, Gan Zhao, and Bin Wang, 2021
Precise spatio-temporal interruption of regulatory T cell-mediated CD8+ T cell suppression leads to tumor immunity, Xiaoyu Zhou, Shushu Zhao, Yue He, Shuang Geng, Yan Shi, and Bin Wang, 2019
Hepatitis B e antigen induces the expansion of monocytic myeloid-derived suppressor cells to dampen T-cell function in chronic hepatitis B virus infection, Feifei Yang, Xueping Yu, Chenliang Zhou, Richeng Mao, Mengqi Zhu, Haoxiang Zhu, Zhenxuan Ma, Bidisha Mitra, Gan Zhao, Yuxian Huang, Haitao Guo, Bin Wang, Jiming Zhang, 2019
Microneedles Improve The Immunogenicity Of DNA Vaccines, Shijie Zhang, Shushu Zhao, Xiang Jin, Bin Wang and Gan Zhao, 2018
Critical role of regulatory T cells in the latency and stress-induced reactivation of HSV-1, Wencong Yu, Shuang Geng, Yuanzhen Suo, Xunbin Wei, Qiliang Cai, Bing Wu, Xian Zhou, Yan Shi and Bin Wang, 2018
Revisiting GM-CSF as an adjuvant for therapeutic vaccines, Weidong Zhao, Gan Zhao, and Bin Wang, 2017
Biomarkers Distinguish HBeAg Seroconverted from Non-Converted Individuals in Chronic Hepatitis B Patients Treated with a Therapeutic Vaccine, Xian Zhou, Shuang Geng, Shijie Zhang, Weidong Zhao, Yumei Wen, Xuanyi Wang and Bin Wang, 2017
Induced regulatory T cells superimpose their suppressive capacity with effector T cells in lymph nodes via antigen-specific S1p1-dependent egress blockage, Shuang Geng, Yiwei Zhong, Xiaoyu Zhou, Gan Zhao, Xiaoping Xie, Yechun Pei, Hu Liu, Huiyuan Zhang, Yan Shi and Bin Wang, 2017

Therapeutic Vaccines Tolerogenic Vaccines Vaccine Adjuvants Clinical Immunology Biomarkers Immune Tolerance Virus-Host Interaction Immune Regulation Vaccine Development Immunotherapy

Yan Liu - Wuhan University

Wenwen Jing - Fudan University

Wang Jinheng - Guangzhou Medical University

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