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Yongbo Wang
Basic Medical Sciences
Fudan University
Shanghai
Language: Chinese, German, English
Rna Splicing
Cancer
Lung Cancer
Cell Models
Mouse Models
Clinical Samples
Multi-Omics
Molecular Biology
Biochemistry
Rna-Based Therapies
Areas of Focus
- RNA splicing abnormalities and cancer
- Regulation mechanisms and functions of alternative RNA splicing
Work Experience
- 2017-present - Fudan University - Associate Professor, Group Leader
- 2013-2017 - Fudan University - Young Associate Researcher, Group Leader
- 2012-2013 - Max-Delbrück Center for Molecular Medicine - Postdoctoral Researcher
- 2005-2006 - Tibet University Medical College - Teaching Support Teacher
Academic Background & Achievements
- 2009-2012 PhD: Max-Delbrück Center for Molecular Medicine, Free University of Berlin
- 2006-2008 Master's: School of Pharmacy, Shanghai Jiao Tong University
- 2001-2005 Bachelor's: School of Pharmacy, Shanghai Jiao Tong University
Publications
- RNA binding motif protein 10 suppresses lung cancer progression by controlling alternative splicing of eukaryotic translation initiation factor 4H., Sirui Zhang, Yufang Bao, Xianfeng Shen, Yunjian Pan, Yue Sun, Man Xiao, Kexuan Chen, Huanhuan Wei, Ji Zuo, David Saffen, Wei-Xing Zong, Yihua Sun, Zefeng Wang, Yongbo Wang, 2020
- Splicing dysregulation in cancer: from mechanistic understanding to a new class of therapeutic targets., Yongbo Wang, Yufang Bao, Sirui Zhang, Zefeng Wang, 2020
- Autoregulation of RBM10 and cross-regulation of RBM10/RBM5 via alternative splicing-coupled nonsense-mediated decay., Yue Sun, Yufang Bao, Wenjian Han, Fan Song, Xianfeng Shen, Jiawei Zhao, Ji Zuo, David Saffen, Wei Chen, Zefeng Wang, Xintian You, Yongbo Wang, 2017
- Functional analysis reveals that RBM10 mutations contribute to lung adenocarcinoma pathogenesis by deregulating splicing., Jiawei Zhao, Yue Sun, Yin Huang, Fan Song, Zengshu Huang, Yufang Bao, Ji Zuo, David Saffen, Zhen Shao, Wen Liu, Yongbo Wang, 2017
- Integrative analysis revealed the molecular mechanism underlying RBM10-mediated splicing regulation., Yongbo Wang, Andreas Gogol-Döring, Hao Hu, Sebastian Fröhler, Yunxia Ma, Marvin Jens, Jonas Maaskola, Yasuhiro Murakawa, Claudia Quedenau, Markus Landthaler, Vera Kalscheuer, Dagmar Wieczorek, Yang Wang, Yuhui Hu, Wei Chen, 2013
Awards
- 2020: Fudan University Excellence 2025 Scholar Program
