Professor | Rong Zhang | Asia Growth Partners

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Name	Rong Zhang
Contact Information	rong_zhang@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Rong Zhang

Contact Information

rong_zhang@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Basic Medical Sciences
Academic Background & Achievements	2003.09-2008.07 Bachelor's Degree: Nanjing Agricultural University 2008.09-2013.07 Joint PhD: Chinese Academy of Agricultural Sciences and University of Pennsylvania School of Medicine
Work Experience	2019.05-present - Fudan University - Researcher 2014.02-2019.04 - Washington University School of Medicine in St. Louis - Postdoctoral Researcher 2013.08-2014.01 - University of Pennsylvania School of Medicine - Postdoctoral Researcher
Awards	2020: Second Prize of the 'One Health Fund' Excellent Teacher Special Award for COVID-19 Prevention and Control 2020: Fudan University Advanced Individual in Fighting COVID-19 2018: STAT Wunderkinds Award

University/Lab Affiliation and Title

Fudan University

Faculty

Basic Medical Sciences

Academic Background & Achievements

2003.09-2008.07 Bachelor's Degree: Nanjing Agricultural University
2008.09-2013.07 Joint PhD: Chinese Academy of Agricultural Sciences and University of Pennsylvania School of Medicine

Work Experience

2019.05-present - Fudan University - Researcher
2014.02-2019.04 - Washington University School of Medicine in St. Louis - Postdoctoral Researcher
2013.08-2014.01 - University of Pennsylvania School of Medicine - Postdoctoral Researcher

Awards

2020: Second Prize of the 'One Health Fund' Excellent Teacher Special Award for COVID-19 Prevention and Control
2020: Fudan University Advanced Individual in Fighting COVID-19
2018: STAT Wunderkinds Award

Areas of Focus	Mechanisms of cell entry and host tropism of emerging viruses such as coronaviruses, flaviviruses, alphaviruses, and bunyaviruses Viral infection immunity and pathogenesis mechanisms Host-directed antiviral and immune strategies Diagnosis and vaccine development for emerging animal and human viruses
Publications	A genome-wide CRISPR screen identifies host factors that regulate the SARS-CoV-2 entry, Zhu Y#, Feng F#, Hu G#, Wang Y#, Yu Y, Zhu Y, Xu W, Cai X, Sun Z, Han W, Ye R, Qu D, Chen H, Huang X, Ding Q, Xie Y, Cai Q, Yuan Z, Zhang R, 2021 Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals a Broad Potential Host Range of SARS-CoV-2, Liu Y#, Hu G#, Wang Y#, Ren W#, Zhao X, Ji F, Zhu Y, Feng F, Gong M, Ju X, Li C, Hong J, Zhu Y, Cai X, Guo J, Xie M, Dong L, Zhu Z, Xu X, Na J, Wu J, Lan X, Xie Y, Wang X, Yuan Z, Zhang R, Ding Q, 2021 Comparative analysis reveals the genetic determinants of ACE2 required by SARS-CoV-2 for cell entry, Ren W#, Zhu Y#, Wang Y#, Shi H, Yu Y, Hu G, Feng F, Zhao X, Lan J, Wu J, Kenney D, Douam F, Tong Y, Zhong J, Xie Y, Wang X, Yuan Z, Zhou D, Zhang R, Ding Q, 2021 Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids, Zhao B#, Ni C#, Gao R#, Wang Y, Yang L, Wei J, Lv T, Liang J, Zhang Q, Xu W, Xie Y, Wang X, Yuan Z, Liang J, Zhang R, Lin X, 2020 Expression of the Mxra8 receptor promotes alphavirus infection and pathogenesis in mice and Drosophila, Zhang R, Earnest JT, Kim AS, Winkler ES, Desai P, Adams L, Hu GW, Bullock C, Gold B, Cherry S, Diamond MS, 2019 Mxra8 is an entry receptor for multiple arthritogenicalphaviruses, Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE, Doranz BJ, Fremont DH, Diamond MS, 2018 A CRISPR screen defines a signal peptide processing pathway required by flaviviruses, Zhang R, Miner JJ, Gorman MJ, Rausch K, Ramage H, White JP, Zuiani A, Zhang P, Fernandez E, Zhang Q, Dowd KA, Pierson TC, Cherry S, Diamond MS, 2016 The nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU, Zhang R#, Li Y#, Cowley TJ, Steinbrenner AD, Phillips JM, Yount BL, Baric RS, Weiss SR, 2015 Murine AKAP7 has a 2',5'-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene, Gusho E#, Zhang R#, Jha BK#, Thornbrough JM, Dong B, Gaughan C, Elliott R, Weiss SR, Silverman RH, 2014 Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity, Zhang R#, Jha BK#, Ogden KM, Dong B, Zhao L, Elliott R, Patton JT, Silverman RH, Weiss SR, 2013

Areas of Focus

Mechanisms of cell entry and host tropism of emerging viruses such as coronaviruses, flaviviruses, alphaviruses, and bunyaviruses
Viral infection immunity and pathogenesis mechanisms
Host-directed antiviral and immune strategies
Diagnosis and vaccine development for emerging animal and human viruses

Publications

A genome-wide CRISPR screen identifies host factors that regulate the SARS-CoV-2 entry, Zhu Y#, Feng F#, Hu G#, Wang Y#, Yu Y, Zhu Y, Xu W, Cai X, Sun Z, Han W, Ye R, Qu D, Chen H, Huang X, Ding Q, Xie Y, Cai Q*, Yuan Z*, Zhang R*, 2021
Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals a Broad Potential Host Range of SARS-CoV-2, Liu Y#, Hu G#, Wang Y#, Ren W#, Zhao X, Ji F, Zhu Y, Feng F, Gong M, Ju X, Li C, Hong J, Zhu Y, Cai X, Guo J, Xie M, Dong L, Zhu Z, Xu X, Na J, Wu J, Lan X, Xie Y, Wang X, Yuan Z*, Zhang R*, Ding Q*, 2021
Comparative analysis reveals the genetic determinants of ACE2 required by SARS-CoV-2 for cell entry, Ren W#, Zhu Y#, Wang Y#, Shi H, Yu Y, Hu G, Feng F, Zhao X, Lan J, Wu J, Kenney D, Douam F, Tong Y, Zhong J, Xie Y, Wang X, Yuan Z, Zhou D, Zhang R*, Ding Q*, 2021
Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids, Zhao B#*, Ni C#, Gao R#, Wang Y, Yang L, Wei J, Lv T, Liang J, Zhang Q, Xu W, Xie Y, Wang X, Yuan Z, Liang J*, Zhang R*, Lin X*, 2020
Expression of the Mxra8 receptor promotes alphavirus infection and pathogenesis in mice and Drosophila, Zhang R, Earnest JT, Kim AS, Winkler ES, Desai P, Adams L, Hu GW, Bullock C, Gold B, Cherry S, Diamond MS, 2019
Mxra8 is an entry receptor for multiple arthritogenicalphaviruses, Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE, Doranz BJ, Fremont DH, Diamond MS, 2018
A CRISPR screen defines a signal peptide processing pathway required by flaviviruses, Zhang R, Miner JJ, Gorman MJ, Rausch K, Ramage H, White JP, Zuiani A, Zhang P, Fernandez E, Zhang Q, Dowd KA, Pierson TC, Cherry S, Diamond MS, 2016
The nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU, Zhang R#, Li Y#, Cowley TJ, Steinbrenner AD, Phillips JM, Yount BL, Baric RS, Weiss SR, 2015
Murine AKAP7 has a 2',5'-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene, Gusho E#, Zhang R#, Jha BK#, Thornbrough JM, Dong B, Gaughan C, Elliott R, Weiss SR*, Silverman RH*, 2014
Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity, Zhang R#, Jha BK#, Ogden KM, Dong B, Zhao L, Elliott R, Patton JT, Silverman RH*, Weiss SR*, 2013

Coronaviruses Flaviviruses Alphaviruses Bunyaviruses Cell Entry Host Tropism Viral Infection Immunity Pathogenesis Vaccine Development

Shuliang Chen - Wuhan University

Wang Fuyan - Central South University

Hui Zhang - Guangzhou Medical University

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