Upload Avatar (500 x 500)
张荣
Basic Medical Sciences
复旦大学
上海
Language: 中文, 英语
冠状病毒
黄病毒
甲病毒
布尼亚病毒
入胞机制
宿主嗜性
病毒感染
免疫
致病机制
疫苗开发
Areas of Focus
- 冠状病毒、黄病毒、甲病毒、布尼亚病毒等新发病毒的入胞机制与宿主嗜性
- 病毒的感染免疫与致病机制
- 靶向宿主因子的抗病毒与免疫策略
- 重要动物与人类新发病毒的诊断与疫苗开发
Work Experience
- 2019.05-至今 - 复旦大学 - 研究员
- 2014.02-2019.04 - 美国圣路易斯华盛顿大学医学院 - 博士后
- 2013.08-2014.01 - 美国宾夕法尼亚大学医学院 - 博士后
Academic Background & Achievements
- 2003.09-2008.07 本科学位: 南京农业大学
- 2008.09-2013.07 联合博士: 中国农业科学院和美国宾夕法尼亚大学医学院
Publications
- A genome-wide CRISPR screen identifies host factors that regulate the SARS-CoV-2 entry, Zhu Y#, Feng F#, Hu G#, Wang Y#, Yu Y, Zhu Y, Xu W, Cai X, Sun Z, Han W, Ye R, Qu D, Chen H, Huang X, Ding Q, Xie Y, Cai Q*, Yuan Z*, Zhang R*, 2021
- Functional and Genetic Analysis of Viral Receptor ACE2 Orthologs Reveals a Broad Potential Host Range of SARS-CoV-2, Liu Y#, Hu G#, Wang Y#, Ren W#, Zhao X, Ji F, Zhu Y, Feng F, Gong M, Ju X, Li C, Hong J, Zhu Y, Cai X, Guo J, Xie M, Dong L, Zhu Z, Xu X, Na J, Wu J, Lan X, Xie Y, Wang X, Yuan Z*, Zhang R*, Ding Q*, 2021
- Comparative analysis reveals the genetic determinants of ACE2 required by SARS-CoV-2 for cell entry, Ren W#, Zhu Y#, Wang Y#, Shi H, Yu Y, Hu G, Feng F, Zhao X, Lan J, Wu J, Kenney D, Douam F, Tong Y, Zhong J, Xie Y, Wang X, Yuan Z, Zhou D, Zhang R*, Ding Q*, 2021
- Recapitulation of SARS-CoV-2 infection and cholangiocyte damage with human liver ductal organoids, Zhao B#*, Ni C#, Gao R#, Wang Y, Yang L, Wei J, Lv T, Liang J, Zhang Q, Xu W, Xie Y, Wang X, Yuan Z, Liang J*, Zhang R*, Lin X*, 2020
- Expression of the Mxra8 receptor promotes alphavirus infection and pathogenesis in mice and Drosophila, Zhang R, Earnest JT, Kim AS, Winkler ES, Desai P, Adams L, Hu GW, Bullock C, Gold B, Cherry S, Diamond MS, 2019
- Mxra8 is an entry receptor for multiple arthritogenicalphaviruses, Zhang R, Kim AS, Fox JM, Nair S, Basore K, Klimstra WB, Rimkunas R, Fong RH, Lin H, Poddar S, Crowe JE, Doranz BJ, Fremont DH, Diamond MS, 2018
- A CRISPR screen defines a signal peptide processing pathway required by flaviviruses, Zhang R, Miner JJ, Gorman MJ, Rausch K, Ramage H, White JP, Zuiani A, Zhang P, Fernandez E, Zhang Q, Dowd KA, Pierson TC, Cherry S, Diamond MS, 2016
- The nsp1, nsp13, and M proteins contribute to the hepatotropism of murine coronavirus JHM.WU, Zhang R#, Li Y#, Cowley TJ, Steinbrenner AD, Phillips JM, Yount BL, Baric RS, Weiss SR, 2015
- Murine AKAP7 has a 2',5'-phosphodiesterase domain that can complement an inactive murine coronavirus ns2 gene, Gusho E#, Zhang R#, Jha BK#, Thornbrough JM, Dong B, Gaughan C, Elliott R, Weiss SR*, Silverman RH*, 2014
- Homologous 2',5'-phosphodiesterases from disparate RNA viruses antagonize antiviral innate immunity, Zhang R#, Jha BK#, Ogden KM, Dong B, Zhao L, Elliott R, Patton JT, Silverman RH*, Weiss SR*, 2013
Awards
- 2020: “一健康基金”优秀教师新冠肺炎疫情防控特别奖二等奖
- 2020: 复旦大学抗击新冠肺炎疫情先进个人
- 2018: 美国STAT Wunderkinds Award获得者
