Professor | Zhihong Cheng | Asia Growth Partners

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Name	Zhihong Cheng
Contact Information	chengzhh@fudan.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Zhihong Cheng

Contact Information

chengzhh@fudan.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	1998.09 – 2003.06 PhD: China Pharmaceutical University, School of Chinese Materia Medica 1994.09 – 1998.06 Bachelor's: China Pharmaceutical University, School of Chinese Materia Medica
Work Experience	2018.12 - Present - Fudan University, School of Pharmacy - Professor 2009.01 – 2018.12 - Fudan University, School of Pharmacy - Associate Researcher 2005.10 – 2008.08 - University of Maryland at College Park - Postdoctoral Researcher 2003.07 – 2005.09 - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Postdoctoral Researcher
Awards	2011.01: Second Prize in Natural Science by the Ministry of Education - Systematic Research on Ophiopogon japonicus (Third Contributor)

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

1998.09 – 2003.06 PhD: China Pharmaceutical University, School of Chinese Materia Medica
1994.09 – 1998.06 Bachelor's: China Pharmaceutical University, School of Chinese Materia Medica

Work Experience

2018.12 - Present - Fudan University, School of Pharmacy - Professor
2009.01 – 2018.12 - Fudan University, School of Pharmacy - Associate Researcher
2005.10 – 2008.08 - University of Maryland at College Park - Postdoctoral Researcher
2003.07 – 2005.09 - Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences - Postdoctoral Researcher

Awards

2011.01: Second Prize in Natural Science by the Ministry of Education - Systematic Research on Ophiopogon japonicus (Third Contributor)

Areas of Focus	Research on the pharmacological basis and quality control of traditional Chinese medicine Microbial transformation of small molecule natural products
Publications	Screening and identification of neuraminidase inhibitors from Baphicacanthus cusia by a combination of affinity ultrafiltration, HPLC-MS/MS, molecular docking, and fluorescent techniques, Fan Xiaofan, Li Yingzhe, Wu Tao, Cheng Zhihong, 2023 Development of a thin-layer chromatography bioautographic assay for neuraminidase inhibitors hyphenated with electrostatic field induced spray ionisation-mass spectrometry for identification of active Isatis indigotica root compounds, Zang Yichao, Miao Yu, Wu Tao, Cheng Zhihong, 2021 Quantitative 1H nuclear magnetic resonance (qHNMR) methods for accurate purity determination of glucosinolates isolated from Isatis indigotica roots, Guo Qihui, Li Zeyun, Shen Lulu, Xiao Ying, Cheng Zhihong, 2021 Flavonoids rather than alkaloids as the diagnostic constituents to distinguish Sophorae Flavescentis Radix from Sophorae Tonkinensis Radix et Rhizoma: an HPLC fingerprint study, Ding Pei-Lan, He Chang-Ming, Cheng Zhi-Hong, Chen Dao-Feng, 2018 Characterization of flavonol mono-, di-, tri- and tetra-O-glycosides by ultra-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry and its application for identification of flavonol glycosides in Viola tianschanica, Qin Yan, Gao Boyan, Shi Haiming, Cao Jie, Yin Chengle, Lu Weiying, Yu Liangli, Cheng Zhihong, 2017 Direct coupling of thin-layer chromatography-bioautography with electrostatic field induced spray ionization-mass spectrometry for separation and identification of lipase inhibitors in lotus leaves, Zhang Lei, Shi Jiyao, Tang Jihe, Cheng Zhihong, Lu Xiaohui, Kong Yao, Wu Tao, 2017 Regioselective hydroxylation of lathyrane diterpenoids biocatalyzed by microorganisms and its application in integrated synthesis, Wu Yiqing, Yin Chengle, Cao Yue, Liu Xin, Yu Jinxiang, Zhang Jian, Yu Boyang, Cheng Zhihong, 2016 Structure characterization of two novel polysaccharides isolated from the spikes of Prunella vulgaris and their anticomplement activities, Du Dongsheng, Lu Yan, Cheng Zhihong, Chen Daofeng, 2016 Needle trap device as a new sampling and preconcentration approach for volatile organic compounds of herbal medicines and its application to the analysis of volatile components in Viola tianschanica, Qin Yan, Pang Yingming, Cheng Zhihong, 2016 Pterocarpans and triterpenoids from Gueldenstaedtia verna, Yin Chengle, Zhou Jinge, Wu Yiqing, Cao Yue, Wu Tao, Zhang Shoude, Li Honglin, Cheng Zhihong, 2015 Approach to the study of flavone di-C-glycosides by high performance liquid chromatography-tandem ion trap mass spectrometry and its application to characterization of flavonoid composition in Viola yedoensis, Cao Jie, Yin Chengle, Qin Yan, Cheng Zhihong, Chen Daofeng, 2014 Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay, Xiao Guodong, Li Guowen, Chen Liang, Zhang Zijia, Yin Jun-Jie, Wu Tao, Cheng Zhihong, Xiaohui Wei, Zhengtao Wang, 2010 Effects of wheat antioxidants on oxygen diffusion-concentration products in liposomes and key genes for cholesterol biosynthesis and metabolism in primary rat hepatocytes, Cheng Zhihong, Zhou Huiping, Luther Marla, Yin Junjie, Yu Liangli, 2008 Qualitative and quantitative analysis of quaternary ammonium alkaloids from Rhizoma Corydalis by MALDI-FTMS coupled with a special precipitation reaction using Reinecke salt, Cheng Zhihong, Guo Yinlong, Wang Haoyang, Chen Guoqiang, 2006 Biotransformation of quinovic acid glycosides by microbes: direct conversion of the ursane to the oleanane triterpene skeleton by Nocardia sp. NRRL 5646, Cheng Zhihong, Yu Boyang, Geoffrey A. Cordell, Qiu Shengxiang, 2004

Areas of Focus

Research on the pharmacological basis and quality control of traditional Chinese medicine
Microbial transformation of small molecule natural products

Publications

Screening and identification of neuraminidase inhibitors from Baphicacanthus cusia by a combination of affinity ultrafiltration, HPLC-MS/MS, molecular docking, and fluorescent techniques, Fan Xiaofan, Li Yingzhe, Wu Tao, Cheng Zhihong, 2023
Development of a thin-layer chromatography bioautographic assay for neuraminidase inhibitors hyphenated with electrostatic field induced spray ionisation-mass spectrometry for identification of active Isatis indigotica root compounds, Zang Yichao, Miao Yu, Wu Tao, Cheng Zhihong, 2021
Quantitative 1H nuclear magnetic resonance (qHNMR) methods for accurate purity determination of glucosinolates isolated from Isatis indigotica roots, Guo Qihui, Li Zeyun, Shen Lulu, Xiao Ying, Cheng Zhihong, 2021
Flavonoids rather than alkaloids as the diagnostic constituents to distinguish Sophorae Flavescentis Radix from Sophorae Tonkinensis Radix et Rhizoma: an HPLC fingerprint study, Ding Pei-Lan, He Chang-Ming, Cheng Zhi-Hong, Chen Dao-Feng, 2018
Characterization of flavonol mono-, di-, tri- and tetra-O-glycosides by ultra-performance liquid chromatography-electrospray ionization-quadrupole time-of-flight mass spectrometry and its application for identification of flavonol glycosides in Viola tianschanica, Qin Yan, Gao Boyan, Shi Haiming, Cao Jie, Yin Chengle, Lu Weiying, Yu Liangli, Cheng Zhihong, 2017
Direct coupling of thin-layer chromatography-bioautography with electrostatic field induced spray ionization-mass spectrometry for separation and identification of lipase inhibitors in lotus leaves, Zhang Lei, Shi Jiyao, Tang Jihe, Cheng Zhihong, Lu Xiaohui, Kong Yao, Wu Tao, 2017
Regioselective hydroxylation of lathyrane diterpenoids biocatalyzed by microorganisms and its application in integrated synthesis, Wu Yiqing, Yin Chengle, Cao Yue, Liu Xin, Yu Jinxiang, Zhang Jian, Yu Boyang, Cheng Zhihong, 2016
Structure characterization of two novel polysaccharides isolated from the spikes of Prunella vulgaris and their anticomplement activities, Du Dongsheng, Lu Yan, Cheng Zhihong, Chen Daofeng, 2016
Needle trap device as a new sampling and preconcentration approach for volatile organic compounds of herbal medicines and its application to the analysis of volatile components in Viola tianschanica, Qin Yan, Pang Yingming, Cheng Zhihong, 2016
Pterocarpans and triterpenoids from Gueldenstaedtia verna, Yin Chengle, Zhou Jinge, Wu Yiqing, Cao Yue, Wu Tao, Zhang Shoude, Li Honglin, Cheng Zhihong, 2015
Approach to the study of flavone di-C-glycosides by high performance liquid chromatography-tandem ion trap mass spectrometry and its application to characterization of flavonoid composition in Viola yedoensis, Cao Jie, Yin Chengle, Qin Yan, Cheng Zhihong, Chen Daofeng, 2014
Isolation of antioxidants from Psoralea corylifolia fruits using high-speed counter-current chromatography guided by thin layer chromatography-antioxidant autographic assay, Xiao Guodong, Li Guowen, Chen Liang, Zhang Zijia, Yin Jun-Jie, Wu Tao, Cheng Zhihong, Xiaohui Wei, Zhengtao Wang, 2010
Effects of wheat antioxidants on oxygen diffusion-concentration products in liposomes and key genes for cholesterol biosynthesis and metabolism in primary rat hepatocytes, Cheng Zhihong, Zhou Huiping, Luther Marla, Yin Junjie, Yu Liangli, 2008
Qualitative and quantitative analysis of quaternary ammonium alkaloids from Rhizoma Corydalis by MALDI-FTMS coupled with a special precipitation reaction using Reinecke salt, Cheng Zhihong, Guo Yinlong, Wang Haoyang, Chen Guoqiang, 2006
Biotransformation of quinovic acid glycosides by microbes: direct conversion of the ursane to the oleanane triterpene skeleton by Nocardia sp. NRRL 5646, Cheng Zhihong, Yu Boyang, Geoffrey A. Cordell, Qiu Shengxiang, 2004

Traditional Chinese Medicine Pharmacological Basis Quality Control Microbial Transformation Natural Products Small Molecules Herbal Medicine Bioactive Compounds Phytochemistry Drug Discovery

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