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Yiqun Deng
Veterinary Medicine
South China Agricultural University
Guangdong
Language: English, Chinese
Mycotoxins
Molecular Toxicology
Metabolic Transformation
Animal Proteins
Enzymes
Function
Structure
Regulation
Cytochrome P450
Xenobiotics
Areas of Focus
- Molecular Toxicology and Metabolic Transformation of Mycotoxins
- Function, Structure, and Regulation of Animal Proteins (Enzymes)
Work Experience
- 2007-12 to Present - South China Agricultural University - Professor
- 2007-07 to 2007-12 - Weill Medical College of Cornell University - Instructor
- 2002-09 to 2007-06 - Weill Medical College of Cornell University - Postdoctoral Fellow
- 2000-08 to 2002-02 - Hong Kong University of Science & Technology - Visiting Scholar
Academic Background & Achievements
- 1999-09 to 2002-06 Doctorate: Sun Yat-sen University
- 1996-09 to 1999-06 Master's: Zhongshan University of Medical Sciences
- 1991-09 to 1996-06 Bachelor's: Wannan Medical College
- National 'Ten Thousand Talents Program' Leading Talent in Technological Innovation (2016)
- Guangdong Province 'Pearl River Scholar' Distinguished Professor (2009)
- Ministry of Education 'New Century Excellent Talents Support Program' (2008)
Publications
- Cell fate determined by the activation balance between PKR and SPHK1, Han Qiao, Tianqing Jiang, Peiqiang Mu, Xiaoxuan Chen, Xianhui Wen, Zhangsheng Hu, Shulin Tang, Jikai Wen*, Yiqun Deng*, 2020
- Inhibition of EZH2 and Activation of ERRγ Synergistically Suppresses Gastric Cancer by Inhibiting FOXM1 Signaling Pathway, Boyan Huang#, Peiqiang Mu#, Yan Yu, Wenya Zhu, Tianqing Jiang, Rong Deng, Gongkan Feng, Jikai Wen, Xiaofeng Zhu*, Yiqun Deng*, 2020
- Identification of NOVA family proteins as novel β-catenin RNA-binding proteins that promote epithelial-mesenchymal transition, Shulin Tang, Yurong Zhao, Xirong He, Jiahui Zhu, Shuang Chen, Jikai Wen*, Yiqun Deng*, 2020
- Deoxynivalenol induces inhibition of cell proliferation via the Wnt/beta-catenin signaling pathway, Shulin Tang, Shuang Chen, Boyan Huang, Jun Jiang, Jikai Wen, Yiqun Deng*, 2019
- The critical role of porcine cytochrome P450 3A46 in the bioactivation of aflatoxin B1, Haoran Jiang, Jun Wu, Feiyong Zhang, Jikai Wen, Jun Jiang, Yiqun Deng*, 2018
- JNK-AKT-NF-κB controls P-glycoprotein expression to attenuate the cytotoxicity of deoxynivalenol in mammalian cells, Xiaoming Li, Peiqiang Mu, Han Qiao, Jikai Wen, Yiqun Deng*, 2018
- C9orf140, a novel Axin1-interacting protein, mediates the negative feedback loop of Wnt/β-catenin signaling, Jun Jiang, Shulin Tang, Jianhong Xia, Jikai Wen, Shuang Chen, Xiaodong Shu, Michael S. Y. Huen, Yiqun Deng*, 2018
- T-2 toxin induces the expression of porcine CYP3A22 via the upregulation of the transcription factor, NF-Y, Xin Liu, Jikai Wen, Ruohong Chen, Tingting Zhang, Jun Jiang, Yiqun Deng*, 2016
- Role of specificity protein 1, hepatocyte nuclear factor 1α, and pregnane x receptor in the basal and rifampicin-induced transcriptional regulation of porcine cytochrome P450 3A46, Linfeng Dong, Qingmei Chen, Xin Liu, Jikai Wen, Jun Jiang, Yiqun Deng*, 2015
- Transcriptional regulation of chicken cytochrome P450 2D49 (CYP2D49) basal expression by CCAAT/enhancer-binding protein α (C/EBPα) and hepatocyte nuclear factor 4α (HNF4α), Qi Yang, Shulin Tang, Linfeng Dong, Qingmei Chen, Xin Liu, Jun Jiang, Yiqun Deng*, 2014
- Proteomic changes in chicken primary hepatocytes exposed to T-2 toxin are associated with oxidative stress and mitochondrial enhancement, Peiqiang Mu, Ming Xu, Lei Zhang, Kaixin Wu, Jun Wu, Jun Jiang, Qingmei Chen, Lijuan Wang, Xianqing Tang, Yiqun Deng*, 2013
- Trp266 determines the binding specificity of a porcine aflatoxin B1 aldehyde reductase for aflatoxin B1-dialdehyde, Jun Wu, Weiying Xu, Caihui Zhang, Qing Chang, Xianqing Tang, Kangbai Li, Yiqun Deng*, 2013
- The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks, Shirley M.H. Sy#, Jun Jiang#, Wai Sum O, Yiqun Deng*, Michael S.Y. Huen*, 2013
- Ring finger protein RNF169 antagonises the ubiquitin-dependent signaling cascade at sites of DNA damage, Jie Chen, Wanjuan Feng, Jun Jiang, Yiqun Deng*, Michael S.Y. Huen*, 2012
- Integrated transcriptional and proteomic analysis with in vitro biochemical assay reveal the important role of CYP3A46 in T-2 toxin hydroxylation in porcine primary hepatocytes, Jianshe Wang#, Jun Jiang#, Hongxia Zhang, Junping Wang, Hua Cai, Cheng Li, Kangbai Li, Jing Liu, Xuejiang Guo, Guangxun Zou, Dazhi Wang, Yiqun Deng*, Jiayin Dai*, 2011
- Critical roles of ring finger protein RNF8 in replication stress responses, Shirley M.H. Sy#, Jun Jiang#, Sui-sui Dong, Gabriel Tsz-Mei Lok, Jun Wu, Hua Cai, Enoch S.L. Yeung, Jun Huang, Junjie Chen, Yiqun Deng*, Michael S.Y. Huen*, 2011
- Mycotoxins: cytotoxicity and biotransformation in animal cells, Jikai Wen, Peiqiang Mu, Yiqun Deng*, 2016
- A heterospecific leucine zipper tetramer, Yiqun Deng, Jie Liu, Qi Zheng, Qunnu Li, Neville R. Kallenbach, Min Lu, 2008
- Structures and polymorphic interactions of two heptad-repeat regions of the SARS virus S2 protein, Yiqun Deng, Jie Liu, Qi Zheng, Wei Yong, Min Lu, 2006
- Antiparallel four-stranded coiled coil specified by a 3-3-1 hydrophobic heptad repeat, Yiqun Deng, Jie Liu, Qi Zheng, David Eliezer, Neville R. Kallenbach, Min Lu, 2006
- Structure and protein design of a human platelet function inhibitor, Jiayin Dai, Jie Liu, Yiqun Deng, Thomas M. Smith, Min Lu, 2004
Awards
- National Teacher's Ethics Model (2015)
- Guangdong Province Teacher's Ethics Model (2015)
- Outstanding Teacher of Southern Guangdong (2012)
- Fourth China Overseas Chinese Contribution Award (2012)
- Ministry of Education Fok Ying Tung Education Foundation Young Teacher Award (Second Prize) (2012)
- Eleventh Guangdong Ding Ying Science and Technology Award (2012)
- Thirteenth Guangdong Youth May Fourth Medal (2011)
