Professor | Hong Zhu | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Hong Zhu
Contact Information	hongzhu@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

Upload Avatar (500 x 500)

Name

Hong Zhu

Contact Information

hongzhu@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences Visiting Scholar: University of California, Irvine Visiting Scholar: University of Southern California Zhejiang Provincial Outstanding Youth Fund Recipient Selected for Zhejiang Provincial 151 Talent Project
Work Experience	Current - Zhejiang University - Professor
Awards	2008: Second Prize of Zhejiang Provincial Science and Technology Award 2009: Zhejiang Association for Science and Technology Talent Project Funding 2011: Excellent Paper Award at the Frontier Forum of Medical Sciences 2011: Zhejiang Provincial Medical Science and Technology Award 2011: Excellent Young Pharmacologist Award by the Chinese Pharmacological Society 2014: Third Prize of the Chinese Pharmaceutical Association Science and Technology Award 2014: Second Prize of the Seventh Higher Education Teaching Achievement Award of Zhejiang Province 2016: Third Prize of Zhejiang Provincial Natural Science Award 2016: Second Prize of Zhejiang University Teaching Achievement Award 2017: Second Prize of the Ministry of Education's Higher Education Scientific Research Outstanding Achievement Award 2017: Second Prize of Zhejiang Pharmaceutical Association Science and Technology Award 2018: Third Prize of the Chinese Anti-Cancer Association Science and Technology Award 2018: Zhejiang Provincial Outstanding Youth Fund Recipient 2018: Selected for the China-Singapore Scientist Exchange Program 2022: First Prize of Zhejiang Provincial Natural Science Award

University/Lab Affiliation and Title

Zhejiang University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

PhD: Shanghai Institute of Materia Medica, Chinese Academy of Sciences
Visiting Scholar: University of California, Irvine
Visiting Scholar: University of Southern California
Zhejiang Provincial Outstanding Youth Fund Recipient
Selected for Zhejiang Provincial 151 Talent Project

Work Experience

Current - Zhejiang University - Professor

Awards

2008: Second Prize of Zhejiang Provincial Science and Technology Award
2009: Zhejiang Association for Science and Technology Talent Project Funding
2011: Excellent Paper Award at the Frontier Forum of Medical Sciences
2011: Zhejiang Provincial Medical Science and Technology Award
2011: Excellent Young Pharmacologist Award by the Chinese Pharmacological Society
2014: Third Prize of the Chinese Pharmaceutical Association Science and Technology Award
2014: Second Prize of the Seventh Higher Education Teaching Achievement Award of Zhejiang Province
2016: Third Prize of Zhejiang Provincial Natural Science Award
2016: Second Prize of Zhejiang University Teaching Achievement Award
2017: Second Prize of the Ministry of Education's Higher Education Scientific Research Outstanding Achievement Award
2017: Second Prize of Zhejiang Pharmaceutical Association Science and Technology Award
2018: Third Prize of the Chinese Anti-Cancer Association Science and Technology Award
2018: Zhejiang Provincial Outstanding Youth Fund Recipient
2018: Selected for the China-Singapore Scientist Exchange Program
2022: First Prize of Zhejiang Provincial Natural Science Award

Areas of Focus	Tumor Pharmacology
Publications	SDHA/B reduction promotes hepatocellular carcinoma by facilitating the deNEDDylation of cullin1 and stabilizing YAP/TAZ, Yuan T, Zhou T, Qian M, Du J, Liu Y, Wang J, Li Y, Fan G, Yan F, Dai X, Li X, Wu Y, Dong X, He Q, Zhu H, Yang B, 2022 USP10 Promotes Proliferation of Hepatocellular Carcinoma by Deubiquitinating and Stabilizing YAP/TAZ, Zhu H, Yan F, Yuan T, Qian M, Zhou T, Dai X, Cao J, Ying M, Dong X, He Q, Yang B, 2020 Multi-kinase inhibitor CT-707 targets liver cancer by interrupting the hypoxia-activated IGF-1R-YAP axis, Zhu H, Wang DD, Yuan T, Yan FJ, Zeng CM, Dai XY, Chen ZB, Chen Y, Zhou T, Fan GH, Ying M, Cao J, Luo P, Liu XJ, Hu Y, Peng Y, He Q, Yang B, 2018 The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer, Zhu H, Hu Y, Zeng C, Chang L, Ge F, Wang W, Yan F, Zhao Q, Cao J, Ying M, Gu Y, Zheng L, He Q, Yang B, 2020 AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer, Zhu H, Chang L, Yan F, Hu Y, Zeng C, Zhou T, Yuan T, Ying M, Cao J, He Q, Yang B, 2018 Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression, Qian M, Yan F, Wang W, Du J, Yuan T, Wu R, Zhao C, Wang J, Lu J, Zhang B, Lin N, Dong X, Dai X, Dong X, Yang B, Zhu H, He Q, 2021 Discovery of Novel Indazoles as Potent and Selective PI3Kδ Inhibitors with High Efficacy for Treatment of Hepatocellular Carcinoma, Qi J, Wang W, Tang Y, Lou S, Wang J, Yuan T, He Q, Yang B, Zhu H, Cui S, 2022 Deubiquitinating Enzyme USP10 Promotes Hepatocellular Carcinoma Metastasis through Deubiquitinating and Stabilizing Smad4 Protein, Yuan T, Chen Z, Yan F, Qian M, Luo H, Ye S, Dai X, Cao J, Ying M, Yang B, He Q, Zhu H, 2020 Targeting Slug-mediated non-canonical activation of c-Met to overcome chemoresistance in metastatic ovarian cancer cells, Chang L, Hu Y, Fu Y, Zhou T, You J, Du J, Zheng L, Cao J, Ying M, Dai X, Su D, He Q, Zhu H, Yang B, 2019 CT-707, a novel FAK inhibitor, synergizes with Cabozantinib to suppress hepatocellular carcinoma by blocking Cabozantinib-induced FAK activation, Wang DD, Chen Y, Chen ZB, Yan FJ, Dai XY, Ying MD, Cao J, Ma J, Luo PH, Han YX, Peng Y, Sun YH, Zhang H, He QJ, Yang B, Zhu H, 2016

Areas of Focus

Tumor Pharmacology

Publications

SDHA/B reduction promotes hepatocellular carcinoma by facilitating the deNEDDylation of cullin1 and stabilizing YAP/TAZ, Yuan T, Zhou T, Qian M, Du J, Liu Y, Wang J, Li Y, Fan G, Yan F, Dai X, Li X, Wu Y, Dong X, He Q, Zhu H, Yang B, 2022
USP10 Promotes Proliferation of Hepatocellular Carcinoma by Deubiquitinating and Stabilizing YAP/TAZ, Zhu H, Yan F, Yuan T, Qian M, Zhou T, Dai X, Cao J, Ying M, Dong X, He Q, Yang B, 2020
Multi-kinase inhibitor CT-707 targets liver cancer by interrupting the hypoxia-activated IGF-1R-YAP axis, Zhu H, Wang DD, Yuan T, Yan FJ, Zeng CM, Dai XY, Chen ZB, Chen Y, Zhou T, Fan GH, Ying M, Cao J, Luo P, Liu XJ, Hu Y, Peng Y, He Q, Yang B, 2018
The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer, Zhu H, Hu Y, Zeng C, Chang L, Ge F, Wang W, Yan F, Zhao Q, Cao J, Ying M, Gu Y, Zheng L, He Q, Yang B, 2020
AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer, Zhu H, Chang L, Yan F, Hu Y, Zeng C, Zhou T, Yuan T, Ying M, Cao J, He Q, Yang B, 2018
Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression, Qian M, Yan F, Wang W, Du J, Yuan T, Wu R, Zhao C, Wang J, Lu J, Zhang B, Lin N, Dong X, Dai X, Dong X, Yang B, Zhu H, He Q, 2021
Discovery of Novel Indazoles as Potent and Selective PI3Kδ Inhibitors with High Efficacy for Treatment of Hepatocellular Carcinoma, Qi J, Wang W, Tang Y, Lou S, Wang J, Yuan T, He Q, Yang B, Zhu H, Cui S, 2022
Deubiquitinating Enzyme USP10 Promotes Hepatocellular Carcinoma Metastasis through Deubiquitinating and Stabilizing Smad4 Protein, Yuan T, Chen Z, Yan F, Qian M, Luo H, Ye S, Dai X, Cao J, Ying M, Yang B, He Q, Zhu H, 2020
Targeting Slug-mediated non-canonical activation of c-Met to overcome chemoresistance in metastatic ovarian cancer cells, Chang L, Hu Y, Fu Y, Zhou T, You J, Du J, Zheng L, Cao J, Ying M, Dai X, Su D, He Q, Zhu H, Yang B, 2019
CT-707, a novel FAK inhibitor, synergizes with Cabozantinib to suppress hepatocellular carcinoma by blocking Cabozantinib-induced FAK activation, Wang DD, Chen Y, Chen ZB, Yan FJ, Dai XY, Ying MD, Cao J, Ma J, Luo PH, Han YX, Peng Y, Sun YH, Zhang H, He QJ, Yang B, Zhu H, 2016

Yap Taz Oncogenic Transcription Factors Regulation Mechanisms Intervention Strategies Anti-Tumor Drug Targets Candidate Drugs Transcription Factor Regulation Cancer Research Pharmacology

Bo Yang - Zhejiang University

Jiajia Wang - Zhejiang University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us