Professor | 朱虹 | 数字化转型顾问

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Name	朱虹
Contact Information	hongzhu@zju.edu.cn
Language ability	中文, 英语
Province	浙江

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Name

朱虹

Contact Information

hongzhu@zju.edu.cn

Language ability

中文, 英语

Province

浙江

University/Lab Affiliation and Title	浙江大学
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	博士: 中国科学院上海药物研究所访问学者: 美国加州大学尔湾分校访问学者: 南加州大学浙江省杰出青年基金获得者入选浙江省151人才工程
Work Experience	目前 - 浙江大学 - 教授
Awards	2008: 浙江省科学技术奖二等奖 2009: 浙江省科协育才工程资助 2011: 医学科学前沿论坛优秀论文奖 2011: 浙江省医药科技奖 2011: 中国药理学会优秀青年药理学工作者奖 2014: 中国药学会科学技术奖三等奖 2014: 浙江省第七届高等教育教学成果奖二等奖 2016: 浙江省自然科学奖三等奖 2016: 浙江大学教学成果奖二等奖 2017: 教育部高等学校科学研究优秀成果奖二等奖 2017: 浙江省药学会科学技术奖二等奖 2018: 中国抗癌协会科技奖三等奖 2018: 浙江省杰出青年基金获得者 2018: 科技部中新科学家交流计划入选者 2022: 浙江省自然科学奖一等奖

University/Lab Affiliation and Title

浙江大学

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

博士: 中国科学院上海药物研究所
访问学者: 美国加州大学尔湾分校
访问学者: 南加州大学
浙江省杰出青年基金获得者
入选浙江省151人才工程

Work Experience

目前 - 浙江大学 - 教授

Awards

2008: 浙江省科学技术奖二等奖
2009: 浙江省科协育才工程资助
2011: 医学科学前沿论坛优秀论文奖
2011: 浙江省医药科技奖
2011: 中国药理学会优秀青年药理学工作者奖
2014: 中国药学会科学技术奖三等奖
2014: 浙江省第七届高等教育教学成果奖二等奖
2016: 浙江省自然科学奖三等奖
2016: 浙江大学教学成果奖二等奖
2017: 教育部高等学校科学研究优秀成果奖二等奖
2017: 浙江省药学会科学技术奖二等奖
2018: 中国抗癌协会科技奖三等奖
2018: 浙江省杰出青年基金获得者
2018: 科技部中新科学家交流计划入选者
2022: 浙江省自然科学奖一等奖

Areas of Focus	肿瘤药理学
Publications	SDHA/B reduction promotes hepatocellular carcinoma by facilitating the deNEDDylation of cullin1 and stabilizing YAP/TAZ, Yuan T, Zhou T, Qian M, Du J, Liu Y, Wang J, Li Y, Fan G, Yan F, Dai X, Li X, Wu Y, Dong X, He Q, Zhu H, Yang B, 2022 USP10 Promotes Proliferation of Hepatocellular Carcinoma by Deubiquitinating and Stabilizing YAP/TAZ, Zhu H, Yan F, Yuan T, Qian M, Zhou T, Dai X, Cao J, Ying M, Dong X, He Q, Yang B, 2020 Multi-kinase inhibitor CT-707 targets liver cancer by interrupting the hypoxia-activated IGF-1R-YAP axis, Zhu H, Wang DD, Yuan T, Yan FJ, Zeng CM, Dai XY, Chen ZB, Chen Y, Zhou T, Fan GH, Ying M, Cao J, Luo P, Liu XJ, Hu Y, Peng Y, He Q, Yang B, 2018 The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer, Zhu H, Hu Y, Zeng C, Chang L, Ge F, Wang W, Yan F, Zhao Q, Cao J, Ying M, Gu Y, Zheng L, He Q, Yang B, 2020 AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer, Zhu H, Chang L, Yan F, Hu Y, Zeng C, Zhou T, Yuan T, Ying M, Cao J, He Q, Yang B, 2018 Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression, Qian M, Yan F, Wang W, Du J, Yuan T, Wu R, Zhao C, Wang J, Lu J, Zhang B, Lin N, Dong X, Dai X, Dong X, Yang B, Zhu H, He Q, 2021 Discovery of Novel Indazoles as Potent and Selective PI3Kδ Inhibitors with High Efficacy for Treatment of Hepatocellular Carcinoma, Qi J, Wang W, Tang Y, Lou S, Wang J, Yuan T, He Q, Yang B, Zhu H, Cui S, 2022 Deubiquitinating Enzyme USP10 Promotes Hepatocellular Carcinoma Metastasis through Deubiquitinating and Stabilizing Smad4 Protein, Yuan T, Chen Z, Yan F, Qian M, Luo H, Ye S, Dai X, Cao J, Ying M, Yang B, He Q, Zhu H, 2020 Targeting Slug-mediated non-canonical activation of c-Met to overcome chemoresistance in metastatic ovarian cancer cells, Chang L, Hu Y, Fu Y, Zhou T, You J, Du J, Zheng L, Cao J, Ying M, Dai X, Su D, He Q, Zhu H, Yang B, 2019 CT-707, a novel FAK inhibitor, synergizes with Cabozantinib to suppress hepatocellular carcinoma by blocking Cabozantinib-induced FAK activation, Wang DD, Chen Y, Chen ZB, Yan FJ, Dai XY, Ying MD, Cao J, Ma J, Luo PH, Han YX, Peng Y, Sun YH, Zhang H, He QJ, Yang B, Zhu H, 2016

Areas of Focus

肿瘤药理学

Publications

SDHA/B reduction promotes hepatocellular carcinoma by facilitating the deNEDDylation of cullin1 and stabilizing YAP/TAZ, Yuan T, Zhou T, Qian M, Du J, Liu Y, Wang J, Li Y, Fan G, Yan F, Dai X, Li X, Wu Y, Dong X, He Q, Zhu H, Yang B, 2022
USP10 Promotes Proliferation of Hepatocellular Carcinoma by Deubiquitinating and Stabilizing YAP/TAZ, Zhu H, Yan F, Yuan T, Qian M, Zhou T, Dai X, Cao J, Ying M, Dong X, He Q, Yang B, 2020
Multi-kinase inhibitor CT-707 targets liver cancer by interrupting the hypoxia-activated IGF-1R-YAP axis, Zhu H, Wang DD, Yuan T, Yan FJ, Zeng CM, Dai XY, Chen ZB, Chen Y, Zhou T, Fan GH, Ying M, Cao J, Luo P, Liu XJ, Hu Y, Peng Y, He Q, Yang B, 2018
The SIRT2-mediated deacetylation of AKR1C1 is required for suppressing its pro-metastasis function in Non-Small Cell Lung Cancer, Zhu H, Hu Y, Zeng C, Chang L, Ge F, Wang W, Yan F, Zhao Q, Cao J, Ying M, Gu Y, Zheng L, He Q, Yang B, 2020
AKR1C1 Activates STAT3 to Promote the Metastasis of Non-Small Cell Lung Cancer, Zhu H, Chang L, Yan F, Hu Y, Zeng C, Zhou T, Yuan T, Ying M, Cao J, He Q, Yang B, 2018
Deubiquitinase JOSD2 stabilizes YAP/TAZ to promote cholangiocarcinoma progression, Qian M, Yan F, Wang W, Du J, Yuan T, Wu R, Zhao C, Wang J, Lu J, Zhang B, Lin N, Dong X, Dai X, Dong X, Yang B, Zhu H, He Q, 2021
Discovery of Novel Indazoles as Potent and Selective PI3Kδ Inhibitors with High Efficacy for Treatment of Hepatocellular Carcinoma, Qi J, Wang W, Tang Y, Lou S, Wang J, Yuan T, He Q, Yang B, Zhu H, Cui S, 2022
Deubiquitinating Enzyme USP10 Promotes Hepatocellular Carcinoma Metastasis through Deubiquitinating and Stabilizing Smad4 Protein, Yuan T, Chen Z, Yan F, Qian M, Luo H, Ye S, Dai X, Cao J, Ying M, Yang B, He Q, Zhu H, 2020
Targeting Slug-mediated non-canonical activation of c-Met to overcome chemoresistance in metastatic ovarian cancer cells, Chang L, Hu Y, Fu Y, Zhou T, You J, Du J, Zheng L, Cao J, Ying M, Dai X, Su D, He Q, Zhu H, Yang B, 2019
CT-707, a novel FAK inhibitor, synergizes with Cabozantinib to suppress hepatocellular carcinoma by blocking Cabozantinib-induced FAK activation, Wang DD, Chen Y, Chen ZB, Yan FJ, Dai XY, Ying MD, Cao J, Ma J, Luo PH, Han YX, Peng Y, Sun YH, Zhang H, He QJ, Yang B, Zhu H, 2016

Yap Taz 致癌转录因子调控机制干预策略抗肿瘤药物靶点候选药物转录因子调控癌症研究药理学

王佳佳 - 浙江大学

杨波 - 浙江大学

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