Professor | Jiajia Wang | Asia Growth Partners

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Name	Jiajia Wang
Contact Information	wjiajia@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

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Name

Jiajia Wang

Contact Information

wjiajia@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	2008/09 – 2019/06 Bachelor's/Master's/PhD: Zhejiang University College of Pharmacy
Work Experience	2020/11 – Present - Zhejiang University College of Pharmacy - Distinguished Researcher 2016/11 – 2020/08 - Cincinnati Children's Hospital Medical Center - Visiting Scholar/Postdoctoral Fellow

University/Lab Affiliation and Title

Zhejiang University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

2008/09 – 2019/06 Bachelor's/Master's/PhD: Zhejiang University College of Pharmacy

Work Experience

2020/11 – Present - Zhejiang University College of Pharmacy - Distinguished Researcher
2016/11 – 2020/08 - Cincinnati Children's Hospital Medical Center - Visiting Scholar/Postdoctoral Fellow

Areas of Focus	Neuropharmacology Immunopharmacology Neuro/Immunotoxicology
Publications	Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling, Wang, J. , Wang JY, Hong W, Zhang L, Song L, Shi Q, Shao Y, Hao G, Fang C, Qiu Y, Yang L, Yang Z, Wang J, Cao J, Yang B, He Q, Weng Q.#, 2021 EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP and senescence pathways, Wang, J., Yang, L., Dong, C., Wang, JC., Xu, L., Qiu, Y., Weng, Q., Zhao, C., Xin, M. and Lu. QR.#, 2020 CTCF-dependent chromatin architecture and SUZ12/PRC2 complex recruitment are required for peripheral myelination and repair, Wang JC., Wang, J., Yang, L., Zhao, C., Wu, L., Xu, L., Zhang, F., Weng, Q.#, Wegner, M. and Lu, QR.#, 2020 Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis, Weng, Q., Wang, JC., Wang, J., He, D., Cheng, Z., Zhang, F., Verma R., Xu, L., Dong, X., He, X., Potter, A., Zhang, L., Xin, X., Blackshear, P.J., Rich, J.N., He, Q., Suvà, M., Waclaw, R. Potter, S., Yu, G. and Lu, QR.#, 2019 Sapidolide A alleviates acetaminophen-induced acute liver injury by inhibiting NLRP3 inflammasome activation in macrophages, Wang JC, Shi Q, Zhou Q, Zhang L, Qiu Y, Lou D, Zhou L, Yang B, He Q, Weng Q, Wang J#, 2022 Targeting PI3K/AKT Signaling for the Treatment of Idiopathic Pulmonary Fibrosis, Wang JC, Hu K, Cai X, Yang B, He Q, Wang, J.#, Weng Q#, 2022 Emerging views of OPTN (optineurin) function in the autophagic process associated with disease, Qiu Y, Wang J, Li H, Wang J#, He Q#, Weng Q#, 2021 Convergent epigenetic regulation of glial plasticity in myelin repair and brain tumorigenesis: A focus on histone modifying enzymes, Wang, J. and Lu. QR.#, 2020 New insights of CCR7 signaling in dendritic cell migration and inflammatory diseases, Hong WX, Yang B, He QJ, Wang J#, Weng QJ#, 2022 Natural Products: Potential Treatments for Cisplatin Nephrotoxicity, Fang, C., Lou, D.*, Zhou, L., Wang, JC., Yang, B., He, Q., Wang, J.# and Weng, Q.#, 2021

Areas of Focus

Neuropharmacology
Immunopharmacology
Neuro/Immunotoxicology

Publications

Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling, Wang, J. *, Wang JY*, Hong W*, Zhang L, Song L, Shi Q, Shao Y, Hao G, Fang C, Qiu Y, Yang L, Yang Z, Wang J, Cao J, Yang B, He Q, Weng Q.#, 2021
EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP and senescence pathways, Wang, J., Yang, L., Dong, C., Wang, JC., Xu, L., Qiu, Y., Weng, Q., Zhao, C., Xin, M. and Lu. QR.#, 2020
CTCF-dependent chromatin architecture and SUZ12/PRC2 complex recruitment are required for peripheral myelination and repair, Wang JC.*, Wang, J.*, Yang, L.*, Zhao, C., Wu, L., Xu, L., Zhang, F., Weng, Q.#, Wegner, M. and Lu, QR.#, 2020
Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis, Weng, Q.*, Wang, JC.*, Wang, J.*, He, D.*, Cheng, Z., Zhang, F., Verma R., Xu, L., Dong, X., He, X., Potter, A., Zhang, L., Xin, X., Blackshear, P.J., Rich, J.N., He, Q., Suvà, M., Waclaw, R. Potter, S., Yu, G. and Lu, QR.#, 2019
Sapidolide A alleviates acetaminophen-induced acute liver injury by inhibiting NLRP3 inflammasome activation in macrophages, Wang JC*, Shi Q*, Zhou Q*, Zhang L, Qiu Y, Lou D, Zhou L, Yang B, He Q, Weng Q, Wang J#, 2022
Targeting PI3K/AKT Signaling for the Treatment of Idiopathic Pulmonary Fibrosis, Wang JC*, Hu K*, Cai X, Yang B, He Q, Wang, J.#, Weng Q#, 2022
Emerging views of OPTN (optineurin) function in the autophagic process associated with disease, Qiu Y, Wang J, Li H, Wang J#, He Q#, Weng Q#, 2021
Convergent epigenetic regulation of glial plasticity in myelin repair and brain tumorigenesis: A focus on histone modifying enzymes, Wang, J. and Lu. QR.#, 2020
New insights of CCR7 signaling in dendritic cell migration and inflammatory diseases, Hong WX, Yang B, He QJ, Wang J#, Weng QJ#, 2022
Natural Products: Potential Treatments for Cisplatin Nephrotoxicity, Fang, C.*, Lou, D.*, Zhou, L., Wang, JC., Yang, B., He, Q., Wang, J.# and Weng, Q.#, 2021

Neuropharmacology: Multiple Sclerosis Stroke Spinal Cord Injury Peripheral Nerve Injury Demyelination Pathogenesis Intervention Strategies Neurotoxicity Immune Cells Autoimmunity Immunopharmacology: Macrophages Dendritic Cells Autoimmune Diseases Immunotoxicity Drug Targets Molecular Mechanisms Therapeutic Strategies Neuro/Immunotoxicology: Clinical Drugs Research Clinical Studies Drug Safety Toxicology Pharmacology

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