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Jiajia Wang
Pharmaceutical Sciences
Zhejiang University
Zhejiang
Language: Chinese, English
Neuropharmacology: Multiple Sclerosis
Stroke
Spinal Cord Injury
Peripheral Nerve Injury
Demyelination
Pathogenesis
Intervention Strategies
Neurotoxicity
Immune Cells
Autoimmunity
Immunopharmacology: Macrophages
Dendritic Cells
Autoimmune Diseases
Immunotoxicity
Drug Targets
Molecular Mechanisms
Therapeutic Strategies
Neuro/Immunotoxicology: Clinical Drugs
Research
Clinical Studies
Drug Safety
Toxicology
Pharmacology
Areas of Focus
- Neuropharmacology
- Immunopharmacology
- Neuro/Immunotoxicology
Work Experience
- 2020/11 – Present - Zhejiang University College of Pharmacy - Distinguished Researcher
- 2016/11 – 2020/08 - Cincinnati Children's Hospital Medical Center - Visiting Scholar/Postdoctoral Fellow
Academic Background & Achievements
- 2008/09 – 2019/06 Bachelor's/Master's/PhD: Zhejiang University College of Pharmacy
Publications
- Optineurin modulates the maturation of dendritic cells to regulate autoimmunity through JAK2-STAT3 signaling, Wang, J. *, Wang JY*, Hong W*, Zhang L, Song L, Shi Q, Shao Y, Hao G, Fang C, Qiu Y, Yang L, Yang Z, Wang J, Cao J, Yang B, He Q, Weng Q.#, 2021
- EED-mediated histone methylation is critical for CNS myelination and remyelination by inhibiting WNT, BMP and senescence pathways, Wang, J., Yang, L., Dong, C., Wang, JC., Xu, L., Qiu, Y., Weng, Q., Zhao, C., Xin, M. and Lu. QR.#, 2020
- CTCF-dependent chromatin architecture and SUZ12/PRC2 complex recruitment are required for peripheral myelination and repair, Wang JC.*, Wang, J.*, Yang, L.*, Zhao, C., Wu, L., Xu, L., Zhang, F., Weng, Q.#, Wegner, M. and Lu, QR.#, 2020
- Single-Cell Transcriptomics Uncovers Glial Progenitor Diversity and Cell Fate Determinants during Development and Gliomagenesis, Weng, Q.*, Wang, JC.*, Wang, J.*, He, D.*, Cheng, Z., Zhang, F., Verma R., Xu, L., Dong, X., He, X., Potter, A., Zhang, L., Xin, X., Blackshear, P.J., Rich, J.N., He, Q., Suvà, M., Waclaw, R. Potter, S., Yu, G. and Lu, QR.#, 2019
- Sapidolide A alleviates acetaminophen-induced acute liver injury by inhibiting NLRP3 inflammasome activation in macrophages, Wang JC*, Shi Q*, Zhou Q*, Zhang L, Qiu Y, Lou D, Zhou L, Yang B, He Q, Weng Q, Wang J#, 2022
- Targeting PI3K/AKT Signaling for the Treatment of Idiopathic Pulmonary Fibrosis, Wang JC*, Hu K*, Cai X, Yang B, He Q, Wang, J.#, Weng Q#, 2022
- Emerging views of OPTN (optineurin) function in the autophagic process associated with disease, Qiu Y, Wang J, Li H, Wang J#, He Q#, Weng Q#, 2021
- Convergent epigenetic regulation of glial plasticity in myelin repair and brain tumorigenesis: A focus on histone modifying enzymes, Wang, J. and Lu. QR.#, 2020
- New insights of CCR7 signaling in dendritic cell migration and inflammatory diseases, Hong WX, Yang B, He QJ, Wang J#, Weng QJ#, 2022
- Natural Products: Potential Treatments for Cisplatin Nephrotoxicity, Fang, C.*, Lou, D.*, Zhou, L., Wang, JC., Yang, B., He, Q., Wang, J.# and Weng, Q.#, 2021
