1990-1995 Bachelor's: Shanghai Medical University, Pharmacology
2014 – Present - Fudan University, School of Pharmacy - Professor
2005 – 2014 - Fudan University, School of Pharmacy - Associate Researcher
2000 – 2005 - Johns Hopkins University - Postdoctoral Researcher
First Prize in National Teaching Achievement Award for Pharmacy Professional Degree Graduate Education (2020)
Research
Metabolic Pharmacology Non-excitable Cell Ion Channels and Transporters In Vivo and In Vitro Pharmacological Activity Evaluation
Emerging role for branched-chain amino acids metabolism in fibrosis, WU T, WANG M, NING F, ZHOU S, HU X, XIN H, REILLY S, ZHANG X, 2023
SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development, ZHOU S, LV P, LI M, CHEN Z, XIN H, REILLY S, ZHANG X, 2023
Slo1 deficiency impaired skeletal muscle regeneration and slow-twitch fibre formation, XIA C, WANG Y, JIANG T, HU Y, CHEN Y, MA X, ZHANG X, GAO Y, 2023
The deubiquitinase USP5 promotes cholangiocarcinoma progression by stabilizing YBX1, NING F, DU L, LI J, WU T, ZHOU J, CHEN Z, HU X, ZHANG Y, LUAN X, XIN H, YUAN C, ZHANG X, 2024
Role of organellar Ca2+-activated K+ channels in disease development, JIANG L, LI J, REILLY S, XIN H, GUO N, ZHANG X, 2023
Olmesartan alleviates SARS-CoV-2 envelope protein induced renal fibrosis by regulating HMGB1 release and autophagic degradation of TGF-beta1, ZHOU S, YU Z, CHEN Z, NING F, HU X, WU T, LI M, XIN H, REILLY S, ZHANG X, 2023
Association of Glycosylation-Related Genes with Different Patterns of Immune Profiles and Prognosis in Cervical Cancer, JING W, ZHANG R, CHEN X, ZHANG X, QIU J, 2023
A Novel Role of BK Channel Activity in Preventing Development of Renal Fibrosis, WANG Y, WANG M, REN D, NING F, TAO J, XIE W, EATON D, JIANG G, FARRIS A, XIN H, CAI H, ZHANG X, 2022
Ceria nanoparticles ameliorates renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis, WANG M, ZENG F, NING F, WANG Y, ZHOU S, HE J, LI C, WANG C, SUN X, ZHANG D, XIAO J, HU P, REILLY S, XIN H, XU X, ZHANG X, 2022
Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling, NING F L, TAO J, LI D D, TIAN L L, WANG M L, REILLY S, LIU C, CAI H, XIN H, ZHANG X M, 2022
The impact of senescence on muscle wasting in chronic kidney disease, HUANG Y, WANG B, HASSOUNAH F, PRICE SR, KLEIN J, MOHAMED TMA, WANG Y, PARK J, CAI H, ZHANG X, WANG XH, 2022
TRIM family contribute to tumorigenesis, cancer development, and drug resistance, HUANG N, SUN X L, LI P, LIU X, ZHANG X M, CHEN Q, XIN H, 2022
Predicting unseen antibodies' neutralizability via adaptive graph neural networks, ZHANG J, DU Y S, ZHOU P F, DING J R, XIA S, WANG Q, CHEN F Y, ZHOU M, ZHANG X M, WANG W F, WU H Y, LU L, ZHANG S T, 2022
Entacapone alleviates acute kidney injury by inhibiting ferroptosis, YANG J, SUN X, HUANG N, LI P, HE J, JIANG L, ZHANG X, HAN S, XIN H, 2022
Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3beta-beta-Catenin Pathway in Peritoneal Dialysis, HE J, WANG M, YANG L, XIN H, BIAN F, JIANG G, ZHANG X, 2022
Mesenchymal Stem Cell-Derived Exosomes Attenuate Epithelial-Mesenchymal Transition of HK-2 Cells, YIN S, ZHOU S L, REN D D, ZHANG J, XIN H, HE X Z, GAO H J, HOU J Y, ZENG F, LU Y J, ZHANG X M, FAN M, 2022
Interactions between Human Serum Albumin and Sulfadimethoxine Determined Using Spectroscopy and Molecular Docking, ZHANG Y, CAO Y Q, LI Y, ZHANG X M, 2022
A Novel Bispecific Antibody Targeting PD-L1 and VEGF With Combined Anti-Tumor Activities, CUI X, JIA H, XIN H, ZHANG L, CHEN S, XIA S, LI X, XU W, CHEN X, FENG Y, WEI X, YU H, WANG Y, ZHAN Y, ZHU X, ZHANG X, 2021
BK Channel Deficiency in Osteoblasts Reduces Bone Formation via the Wnt/beta-Catenin Pathway, JIANG L, YANG Q, GAO J, YANG J, HE J, XIN H, ZHANG X, 2021
Structure and function of USP5: Insight into physiological and pathophysiological roles, NING F L, XIN H, LIU J Q, LV C, XU X, WANG M L, WANG Y H, ZHANG W D, ZHANG X M, 2020
The influx/efflux mechanisms of d-peptide ligand of nAChRs across the blood-brain barrier and its therapeutic value in treating glioma, HAN B, XIE W, ZHANG Y, ZHOU S, YANG J, WANG R, SUN Y, WANG X, XU J, CHEN D, WANG Y, LU J, NING F, SHEN F, LIU M, CAI H, XIN H, LU W, ZHANG X, 2020
Regulatory roles of HSPA6 in Actinidia chinensis Planch. root extract (acRoots)-inhibited lung cancer proliferation, WANG L, HOU J, WANG J, ZHU Z, ZHANG W, ZHANG X, SHEN H, WANG X, 2020
Mechanism of Regulation of Big-Conductance Ca(2+)-Activated K(+) Channels by mTOR Complex 2 in Podocytes, WANG Y, TAO J, WANG M, YANG L, NING F, XIN H, XU X, CAI H, ZHANG W, YU K, ZHANG X, 2019
BK ablation attenuates osteoblast bone formation via integrin pathway, WANG Y, GUO Q, HEI H, TAO J, ZHOU Y, DONG J, XIN H, CAI H, GAO J, YU K, REILLY S, YIN P, ZHANG X, 2019
Bilobetin induces kidney injury by influencing cGMP-mediated AQP-2 trafficking and podocyte cell cycle arrest, WANG Q, WU Z L, YUAN X, DONG H Y, XU X, XIN H, WANG Y H, ZHANG J B, CHEN L, LI H L, ZHANG X M, ZHANG W D, 2019
Area of Focus
Antiviral | Traditional Chinese Medicine | Efficacy Evaluation | Mechanism Of Action | Host Barrier Protection | Immune Regulation | Anti-Infective Drugs | Research | Discovery | Evaluation