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Xue-Mei Zhang
Pharmaceutical Sciences
Fudan University
Shanghai
Language: Chinese, English
Metabolism
Pharmacology
Ion Channels
Transporters
Signal Regulation
In Vivo
In Vitro
Pharmacological Activity
Evaluation
Research
Areas of Focus
- Metabolic Pharmacology
- Non-excitable Cell Ion Channels and Transporters
- In Vivo and In Vitro Pharmacological Activity Evaluation
Work Experience
- 2014 – Present - Fudan University, School of Pharmacy - Professor
- 2005 – 2014 - Fudan University, School of Pharmacy - Associate Researcher
- 2000 – 2005 - Johns Hopkins University - Postdoctoral Researcher
Academic Background & Achievements
- 1995-2000 PhD: Fudan University, Pharmacology
- 1990-1995 Bachelor's: Shanghai Medical University, Pharmacology
Publications
- Emerging role for branched-chain amino acids metabolism in fibrosis, WU T, WANG M, NING F, ZHOU S, HU X, XIN H, REILLY S, ZHANG X, 2023
- SARS-CoV-2 E protein: Pathogenesis and potential therapeutic development, ZHOU S, LV P, LI M, CHEN Z, XIN H, REILLY S, ZHANG X, 2023
- Slo1 deficiency impaired skeletal muscle regeneration and slow-twitch fibre formation, XIA C, WANG Y, JIANG T, HU Y, CHEN Y, MA X, ZHANG X, GAO Y, 2023
- The deubiquitinase USP5 promotes cholangiocarcinoma progression by stabilizing YBX1, NING F, DU L, LI J, WU T, ZHOU J, CHEN Z, HU X, ZHANG Y, LUAN X, XIN H, YUAN C, ZHANG X, 2024
- Role of organellar Ca2+-activated K+ channels in disease development, JIANG L, LI J, REILLY S, XIN H, GUO N, ZHANG X, 2023
- Olmesartan alleviates SARS-CoV-2 envelope protein induced renal fibrosis by regulating HMGB1 release and autophagic degradation of TGF-beta1, ZHOU S, YU Z, CHEN Z, NING F, HU X, WU T, LI M, XIN H, REILLY S, ZHANG X, 2023
- Association of Glycosylation-Related Genes with Different Patterns of Immune Profiles and Prognosis in Cervical Cancer, JING W, ZHANG R, CHEN X, ZHANG X, QIU J, 2023
- A Novel Role of BK Channel Activity in Preventing Development of Renal Fibrosis, WANG Y, WANG M, REN D, NING F, TAO J, XIE W, EATON D, JIANG G, FARRIS A, XIN H, CAI H, ZHANG X, 2022
- Ceria nanoparticles ameliorates renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis, WANG M, ZENG F, NING F, WANG Y, ZHOU S, HE J, LI C, WANG C, SUN X, ZHANG D, XIAO J, HU P, REILLY S, XIN H, XU X, ZHANG X, 2022
- Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling, NING F L, TAO J, LI D D, TIAN L L, WANG M L, REILLY S, LIU C, CAI H, XIN H, ZHANG X M, 2022
- The impact of senescence on muscle wasting in chronic kidney disease, HUANG Y, WANG B, HASSOUNAH F, PRICE SR, KLEIN J, MOHAMED TMA, WANG Y, PARK J, CAI H, ZHANG X, WANG XH, 2022
- TRIM family contribute to tumorigenesis, cancer development, and drug resistance, HUANG N, SUN X L, LI P, LIU X, ZHANG X M, CHEN Q, XIN H, 2022
- Predicting unseen antibodies' neutralizability via adaptive graph neural networks, ZHANG J, DU Y S, ZHOU P F, DING J R, XIA S, WANG Q, CHEN F Y, ZHOU M, ZHANG X M, WANG W F, WU H Y, LU L, ZHANG S T, 2022
- Entacapone alleviates acute kidney injury by inhibiting ferroptosis, YANG J, SUN X, HUANG N, LI P, HE J, JIANG L, ZHANG X, HAN S, XIN H, 2022
- Astragaloside IV Alleviates Intestinal Barrier Dysfunction via the AKT-GSK3beta-beta-Catenin Pathway in Peritoneal Dialysis, HE J, WANG M, YANG L, XIN H, BIAN F, JIANG G, ZHANG X, 2022
- Mesenchymal Stem Cell-Derived Exosomes Attenuate Epithelial-Mesenchymal Transition of HK-2 Cells, YIN S, ZHOU S L, REN D D, ZHANG J, XIN H, HE X Z, GAO H J, HOU J Y, ZENG F, LU Y J, ZHANG X M, FAN M, 2022
- Interactions between Human Serum Albumin and Sulfadimethoxine Determined Using Spectroscopy and Molecular Docking, ZHANG Y, CAO Y Q, LI Y, ZHANG X M, 2022
- A Novel Bispecific Antibody Targeting PD-L1 and VEGF With Combined Anti-Tumor Activities, CUI X, JIA H, XIN H, ZHANG L, CHEN S, XIA S, LI X, XU W, CHEN X, FENG Y, WEI X, YU H, WANG Y, ZHAN Y, ZHU X, ZHANG X, 2021
- BK Channel Deficiency in Osteoblasts Reduces Bone Formation via the Wnt/beta-Catenin Pathway, JIANG L, YANG Q, GAO J, YANG J, HE J, XIN H, ZHANG X, 2021
- Structure and function of USP5: Insight into physiological and pathophysiological roles, NING F L, XIN H, LIU J Q, LV C, XU X, WANG M L, WANG Y H, ZHANG W D, ZHANG X M, 2020
- The influx/efflux mechanisms of d-peptide ligand of nAChRs across the blood-brain barrier and its therapeutic value in treating glioma, HAN B, XIE W, ZHANG Y, ZHOU S, YANG J, WANG R, SUN Y, WANG X, XU J, CHEN D, WANG Y, LU J, NING F, SHEN F, LIU M, CAI H, XIN H, LU W, ZHANG X, 2020
- Regulatory roles of HSPA6 in Actinidia chinensis Planch. root extract (acRoots)-inhibited lung cancer proliferation, WANG L, HOU J, WANG J, ZHU Z, ZHANG W, ZHANG X, SHEN H, WANG X, 2020
- Mechanism of Regulation of Big-Conductance Ca(2+)-Activated K(+) Channels by mTOR Complex 2 in Podocytes, WANG Y, TAO J, WANG M, YANG L, NING F, XIN H, XU X, CAI H, ZHANG W, YU K, ZHANG X, 2019
- BK ablation attenuates osteoblast bone formation via integrin pathway, WANG Y, GUO Q, HEI H, TAO J, ZHOU Y, DONG J, XIN H, CAI H, GAO J, YU K, REILLY S, YIN P, ZHANG X, 2019
- Bilobetin induces kidney injury by influencing cGMP-mediated AQP-2 trafficking and podocyte cell cycle arrest, WANG Q, WU Z L, YUAN X, DONG H Y, XU X, XIN H, WANG Y H, ZHANG J B, CHEN L, LI H L, ZHANG X M, ZHANG W D, 2019
Awards
- First Prize in National Teaching Achievement Award for Pharmacy Professional Degree Graduate Education (2020)
