Professor | Tingbo Ding | Asia Growth Partners

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Name	Tingbo Ding
Contact Information	tbding@shmu.edu.cn
Language ability	Chinese, English
Province	Shanghai

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Name

Tingbo Ding

Contact Information

tbding@shmu.edu.cn

Language ability

Chinese, English

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	1999 - Master's Degree: Shanghai Medical University 2008 - PhD in Biochemistry and Molecular Biology: Fudan University 2009-2011 - Research Visit: State University of New York Downstate Medical Center Participated in 14 National Natural Science Foundation projects Hosted 1 Shanghai Natural Science Foundation project Published papers in JLR, ATVB, JBC, JMC, EJMC
Work Experience	1999-present - Shanghai Medical University/Fudan University - Various roles including Assistant, Lecturer, Senior Experimenter

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

1999 - Master's Degree: Shanghai Medical University
2008 - PhD in Biochemistry and Molecular Biology: Fudan University
2009-2011 - Research Visit: State University of New York Downstate Medical Center
Participated in 14 National Natural Science Foundation projects
Hosted 1 Shanghai Natural Science Foundation project
Published papers in JLR, ATVB, JBC, JMC, EJMC

Work Experience

1999-present - Shanghai Medical University/Fudan University - Various roles including Assistant, Lecturer, Senior Experimenter

Areas of Focus	Lipid Metabolism Drug Development
Publications	Comparison of methods for detecting lysophosphatidylcholine acyltransferase (LPAFAT) activity, Jiachun Hu, Jibin Dong, Bin Lou, Yingxia Li, Xiancheng Jiang, Tingbo Ding, 2020 A novel assay for measuring recombinant human lysophosphatidylcholine acyltransferase 3 activity, Xinming Du, Jiachun Hu, Qing Zhang, Qi Liu, Xinin Xiang, Jibin Dong, Bin Lou, Shuhua He, Xiang Gu, Yu Cao, Yingxia Li, Tingbo Ding, 2019 Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor, Yali Li, Taomin Huang, Bin Lou, Deyong Ye, Xiangyu Qi, Xiaoxia Li, Shuang Hu, Tingbo Ding, Chen Yan, Yang Cao, Mingguang Mo, Jibin Dong, Min Wei, Yong Chu, Huiti Li, Xian-Cheng Jiang, Nengneng Cheng, Lu Zhou, 2019 2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity, Bin Lou, Qi Liu, Jiahui Hou, Inamul Kabir, Peipei Liu, Tingbo Ding, Jibin Dong, Mingguang Mo, Yang Chen, Hai H. Bui, Kenneth Roth, Yu Cao, Xian-Cheng Jiang, 2018 Lysophosphatidylcholine acyltransferase 3 deficiency impairs 3T3L1 cell adipogenesis through activating Wnt/β-catenin pathway, Chunyan Feng, Bin Lou, Jibin Dong, Zhiqiang Li, Yunqin Chen, Yue Li, Xuemei Zhang, Xian-Cheng Jiang, Tingbo Ding, 2018 Deficiency in Lysophosphatidylcholine Acyltransferase 3 Reduces Plasma Levels of Lipids by Reducing Lipid Absorption in Mice, Zhiqiang Li, Hui Jiang, Tingbo Ding, Caixia Lou, HH Bui, Ming-Shang Kuo, Xian-Cheng Jiang, 2015 Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors, Yali Li, Xiangyu Qi, Hui Jiang, Xiaodong Deng, Yanping Dong, Tingbo Ding, Lu Zhou, Peng Men, Yong Chu, Renxiao Wang, Xian-Cheng Jiang, Deyong Ye, 2015 All members in Sphingomyelin Synthase Gene Family Have Ceramide Phosphoethanolamine Synthase Activity, Tingbo Ding, Inamul Kabir, Yue Li, Caixia Lou, Amirfarbod Yazdanyar, Jiachen Xu, Jibin Dong, Hongwen Zhou, Taesik Park, Mohamed Boutjdir, Zhiqiang Li, Xian-Cheng Jiang, 2015 Sphingomyelin synthase activity measurement by the fluorescent product in cell culture medium or animal plasma, Tingbo Ding, Jibin Dong, Bin Lou, Xian-Cheng Jiang, 2014 Identification of small molecule sphingomyelin synthase inhibitors, Xiaodong Deng, Fu Lin, Ya Zhang, Yan Li, Lu Zhou, Bin Lou, Yue Li, Jibin Dong, Tingbo Ding, Xiancheng Jiang, Renxiao Wang, Deyong Ye, 2014 Sphingomyelin synthase 2 activity and liver steatosis: an effect of ceramide-mediated peroxisome proliferator-activated receptor γ2 suppression, Yue Li, Jibin Dong, Tingbo Ding, Ming-Shang Kuo, Guoqing Cao, Xian-Cheng Jiang, Zhiqiang Li, 2013 Lysophosphatidylcholine acyltransferase 3 knockdown-mediated liver lysophosphatidylcholine accumulation promotes very low density lipoprotein production by enhancing microsomal triglyceride transfer protein expression, Zhiqiang Li, Tingbo Ding, Xiaoyue Pan, Yan Li, Ruohan Li, Philip E. Sanders, Ming-Shang Kuo, M. Mahmood Hussain, Guoqing Cao, Xian-Cheng Jiang, 2012 Subcellular Targeting Domains of Sphingomyelin Synthase 1 and 2, Calvin Yeang, Tingbo Ding, William J Chirico, Xian-Cheng Jiang, 2011 SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis, Tingbo Ding, Zhiqiang Li, Tiruneh Hailemariam, Sushmita Mukherjee, Frederick R. Maxfield, Man-Ping Wu, Xian-Cheng Jiang, 2008

Areas of Focus

Lipid Metabolism
Drug Development

Publications

Comparison of methods for detecting lysophosphatidylcholine acyltransferase (LPAFAT) activity, Jiachun Hu, Jibin Dong, Bin Lou, Yingxia Li, Xiancheng Jiang, Tingbo Ding, 2020
A novel assay for measuring recombinant human lysophosphatidylcholine acyltransferase 3 activity, Xinming Du, Jiachun Hu, Qing Zhang, Qi Liu, Xinin Xiang, Jibin Dong, Bin Lou, Shuhua He, Xiang Gu, Yu Cao, Yingxia Li, Tingbo Ding, 2019
Discovery, synthesis and anti-atherosclerotic activities of a novel selective sphingomyelin synthase 2 inhibitor, Yali Li, Taomin Huang, Bin Lou, Deyong Ye, Xiangyu Qi, Xiaoxia Li, Shuang Hu, Tingbo Ding, Chen Yan, Yang Cao, Mingguang Mo, Jibin Dong, Min Wei, Yong Chu, Huiti Li, Xian-Cheng Jiang, Nengneng Cheng, Lu Zhou, 2019
2-Hydroxy-oleic acid does not activate sphingomyelin synthase activity, Bin Lou, Qi Liu, Jiahui Hou, Inamul Kabir, Peipei Liu, Tingbo Ding, Jibin Dong, Mingguang Mo, Yang Chen, Hai H. Bui, Kenneth Roth, Yu Cao, Xian-Cheng Jiang, 2018
Lysophosphatidylcholine acyltransferase 3 deficiency impairs 3T3L1 cell adipogenesis through activating Wnt/β-catenin pathway, Chunyan Feng, Bin Lou, Jibin Dong, Zhiqiang Li, Yunqin Chen, Yue Li, Xuemei Zhang, Xian-Cheng Jiang, Tingbo Ding, 2018
Deficiency in Lysophosphatidylcholine Acyltransferase 3 Reduces Plasma Levels of Lipids by Reducing Lipid Absorption in Mice, Zhiqiang Li, Hui Jiang, Tingbo Ding, Caixia Lou, HH Bui, Ming-Shang Kuo, Xian-Cheng Jiang, 2015
Discovery, synthesis and biological evaluation of 2-(4-(N-phenethylsulfamoyl)phenoxy)acetamides (SAPAs) as novel sphingomyelin synthase 1 inhibitors, Yali Li, Xiangyu Qi, Hui Jiang, Xiaodong Deng, Yanping Dong, Tingbo Ding, Lu Zhou, Peng Men, Yong Chu, Renxiao Wang, Xian-Cheng Jiang, Deyong Ye, 2015
All members in Sphingomyelin Synthase Gene Family Have Ceramide Phosphoethanolamine Synthase Activity, Tingbo Ding, Inamul Kabir, Yue Li, Caixia Lou, Amirfarbod Yazdanyar, Jiachen Xu, Jibin Dong, Hongwen Zhou, Taesik Park, Mohamed Boutjdir, Zhiqiang Li, Xian-Cheng Jiang, 2015
Sphingomyelin synthase activity measurement by the fluorescent product in cell culture medium or animal plasma, Tingbo Ding, Jibin Dong, Bin Lou, Xian-Cheng Jiang, 2014
Identification of small molecule sphingomyelin synthase inhibitors, Xiaodong Deng, Fu Lin, Ya Zhang, Yan Li, Lu Zhou, Bin Lou, Yue Li, Jibin Dong, Tingbo Ding, Xiancheng Jiang, Renxiao Wang, Deyong Ye, 2014
Sphingomyelin synthase 2 activity and liver steatosis: an effect of ceramide-mediated peroxisome proliferator-activated receptor γ2 suppression, Yue Li, Jibin Dong, Tingbo Ding, Ming-Shang Kuo, Guoqing Cao, Xian-Cheng Jiang, Zhiqiang Li, 2013
Lysophosphatidylcholine acyltransferase 3 knockdown-mediated liver lysophosphatidylcholine accumulation promotes very low density lipoprotein production by enhancing microsomal triglyceride transfer protein expression, Zhiqiang Li, Tingbo Ding, Xiaoyue Pan, Yan Li, Ruohan Li, Philip E. Sanders, Ming-Shang Kuo, M. Mahmood Hussain, Guoqing Cao, Xian-Cheng Jiang, 2012
Subcellular Targeting Domains of Sphingomyelin Synthase 1 and 2, Calvin Yeang, Tingbo Ding, William J Chirico, Xian-Cheng Jiang, 2011
SMS overexpression and knockdown: impact on cellular sphingomyelin and diacylglycerol metabolism, and cell apoptosis, Tingbo Ding, Zhiqiang Li, Tiruneh Hailemariam, Sushmita Mukherjee, Frederick R. Maxfield, Man-Ping Wu, Xian-Cheng Jiang, 2008

Lipid Metabolism Drug Development Biochemistry Molecular Biology Sphingomyelin Synthase Lpcat3 Sms Inhibitors Pharmacology Research Teaching

Jianzhong Lu - Fudan University

Xue-Mei Zhang - Fudan University

Xin Hong - Fudan University

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