Professor | Xin Hong | Asia Growth Partners

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Name	Xin Hong
Contact Information	xinhong@fudan.edu.cn
Language ability	Chinese, Japanese
Province	Shanghai

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Name

Xin Hong

Contact Information

xinhong@fudan.edu.cn

Language ability

Chinese, Japanese

Province

Shanghai

University/Lab Affiliation and Title	Fudan University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	2000-2005 Ph.D. in Pharmacology: Gunma University, Japan 1994-1997 Master's in Pharmacology: Dalian Medical University 1989-1994 Bachelor's in Clinical Medicine: Dalian Medical University
Work Experience	2016-present - Fudan University - Associate Professor 2014-2016 - National Health and Family Planning Commission - Major New Drug Creation Office 2008-2016 - Fudan University - Lecturer 2006-2008 - Fudan University - Postdoctoral Researcher 2005-2006 - Jikei University School of Medicine, Japan - Researcher 1997-2000 - Dalian Medical University - Lecturer
Awards	Shanghai Pharmaceutical Science and Technology Award/Second Prize: Preclinical study of SCM-198 with unique cardiovascular and cerebrovascular protective effects (Ranked 5th) China Pharmaceutical Association Science and Technology Progress Award/Third Prize: Pharmacodynamic study and preclinical development of SCM-198 (Ranked 5th)

University/Lab Affiliation and Title

Fudan University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

2000-2005 Ph.D. in Pharmacology: Gunma University, Japan
1994-1997 Master's in Pharmacology: Dalian Medical University
1989-1994 Bachelor's in Clinical Medicine: Dalian Medical University

Work Experience

2016-present - Fudan University - Associate Professor
2014-2016 - National Health and Family Planning Commission - Major New Drug Creation Office
2008-2016 - Fudan University - Lecturer
2006-2008 - Fudan University - Postdoctoral Researcher
2005-2006 - Jikei University School of Medicine, Japan - Researcher
1997-2000 - Dalian Medical University - Lecturer

Awards

Shanghai Pharmaceutical Science and Technology Award/Second Prize: Preclinical study of SCM-198 with unique cardiovascular and cerebrovascular protective effects (Ranked 5th)
China Pharmaceutical Association Science and Technology Progress Award/Third Prize: Pharmacodynamic study and preclinical development of SCM-198 (Ranked 5th)

Areas of Focus	Renal Pharmacology, Acute and Chronic Kidney Injury Tumor Pharmacology
Publications	TRIM21 mediates the synergistic effect of Olaparib and Sorafenib by degrading BRCA1 through ubiquitination in TNBC, Huang N, Li P, Sun X, Tong L, Dong X, Zhang X, Duan J, Sheng X, Xin H, 2023 TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury, Sun X, Huang N, Li P, Dong X, Yang J, Zhang X, Zong WX, Gao S, Xin H, 2023 Emerging role for branched-chain amino acids metabolism in fibrosis, Wu T, Wang M, Ning F, Zhou S, Hu X, Xin H, Reilly S, Zhang X, 2023 TRIM family contribute to tumorigenesis, cancer development, and drug resistance, Huang N, Sun X, Li P, Liu X, Zhang X, Chen Q, Xin H, 2022 Entacapone alleviates acute kidney injury by inhibiting ferroptosis, Yang J, Sun X, Huang N, Li P, He J, Jiang L, Zhang X, Han S, Xin H, 2022 Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis, Wang M, Zeng F, Ning F, Wang Y, Zhou S, He J, Li C, Wang C, Sun X, Zhang D, Xiao J, Hu P, Reilly S, Xin H, Xu X, Zhang X, 2022 Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling, Ning FL, Tao J, Li DD, Tian LL, Wang ML, Reilly S, Liu C, Cai H, Xin H, Zhang XM, 2022 The influx/efflux mechanisms of d-peptide ligand of nAChRs across the blood-brain barrier and its therapeutic value in treating glioma, Han B, Xie W, Zhang Y, Zhou S, Yang J, Wang R, Sun Y, Wang X, Xu J, Chen D, Wang Y, Lu J, Ning F, Shen F, Liu M, Cai H, Xin H, Lu W, Zhang X, 2020 Saikosaponin B2 attenuates kidney fibrosis via inhibiting the Hedgehog Pathway, Ren D, Luo J, Li Y, Zhang J, Yang J, Liu J, Zhang X, Cheng N, Xin H*, 2020 AMPK Serves as a Therapeutic Target Against Anemia of Inflammation, Wang M#, Xin H#, Tang W, Li Y, Zhang Z, Fan L, Miao L, Tan B, Wang X, Zhu YZ, 2017 Hydrogen sulfide attenuates inflammatory hepcidin by reducing IL-6 secretion and promoting SIRT1-mediated STAT3 deacetylation, Xin H#, Wang M#, Tang W, Shen Z, Miao L, Wu W, Li C, Wang X, Xin X, Zhu Y, 2016 Establishment and characterization of 7 novel hepatocellular carcinoma cell lines from patient-derived tumor xenografts, Xin H, Wang K, Hu G, Xie F, Ouyang K, Tang X, Wang M, Wen D, Zhu Y, Qin X, 2014

Areas of Focus

Renal Pharmacology, Acute and Chronic Kidney Injury
Tumor Pharmacology

Publications

TRIM21 mediates the synergistic effect of Olaparib and Sorafenib by degrading BRCA1 through ubiquitination in TNBC, Huang N, Li P, Sun X, Tong L, Dong X, Zhang X, Duan J, Sheng X, Xin H*, 2023
TRIM21 ubiquitylates GPX4 and promotes ferroptosis to aggravate ischemia/reperfusion-induced acute kidney injury, Sun X, Huang N, Li P, Dong X, Yang J, Zhang X, Zong WX, Gao S, Xin H*, 2023
Emerging role for branched-chain amino acids metabolism in fibrosis, Wu T, Wang M, Ning F, Zhou S, Hu X, Xin H*, Reilly S*, Zhang X*, 2023
TRIM family contribute to tumorigenesis, cancer development, and drug resistance, Huang N, Sun X, Li P, Liu X, Zhang X*, Chen Q*, Xin H*, 2022
Entacapone alleviates acute kidney injury by inhibiting ferroptosis, Yang J, Sun X, Huang N, Li P, He J, Jiang L, Zhang X, Han S*, Xin H*, 2022
Ceria nanoparticles ameliorate renal fibrosis by modulating the balance between oxidative phosphorylation and aerobic glycolysis, Wang M, Zeng F, Ning F, Wang Y, Zhou S, He J, Li C, Wang C, Sun X, Zhang D, Xiao J, Hu P, Reilly S, Xin H*, Xu X*, Zhang X*, 2022
Activating BK channels ameliorates vascular smooth muscle calcification through Akt signaling, Ning FL, Tao J, Li DD, Tian LL, Wang ML, Reilly S, Liu C, Cai H, Xin H*, Zhang XM*, 2022
The influx/efflux mechanisms of d-peptide ligand of nAChRs across the blood-brain barrier and its therapeutic value in treating glioma, Han B, Xie W, Zhang Y, Zhou S, Yang J, Wang R, Sun Y, Wang X, Xu J, Chen D, Wang Y, Lu J, Ning F, Shen F, Liu M, Cai H, Xin H*, Lu W*, Zhang X*, 2020
Saikosaponin B2 attenuates kidney fibrosis via inhibiting the Hedgehog Pathway, Ren D, Luo J, Li Y, Zhang J, Yang J, Liu J, Zhang X, Cheng N, Xin H*, 2020
AMPK Serves as a Therapeutic Target Against Anemia of Inflammation, Wang M#, Xin H#, Tang W, Li Y, Zhang Z, Fan L, Miao L, Tan B, Wang X, Zhu YZ, 2017
Hydrogen sulfide attenuates inflammatory hepcidin by reducing IL-6 secretion and promoting SIRT1-mediated STAT3 deacetylation, Xin H#, Wang M#, Tang W, Shen Z, Miao L, Wu W, Li C, Wang X, Xin X, Zhu Y, 2016
Establishment and characterization of 7 novel hepatocellular carcinoma cell lines from patient-derived tumor xenografts, Xin H, Wang K, Hu G, Xie F, Ouyang K, Tang X, Wang M, Wen D, Zhu Y, Qin X, 2014

Renal Pharmacology Kidney Injury Acute Kidney Injury Chronic Kidney Injury Pharmacology Renal Protection Nephrology Drug Development Kidney Disease Renal Function

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