Professor | Hao-Shu Wu | Asia Growth Partners

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Name	Hao-Shu Wu
Contact Information	fwhs@zju.edu.cn
Language ability	Chinese, English
Province	Zhejiang

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Name

Hao-Shu Wu

Contact Information

fwhs@zju.edu.cn

Language ability

Chinese, English

Province

Zhejiang

University/Lab Affiliation and Title	Zhejiang University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	2002/03 – 2006/12 PhD in Pharmacology: Zhejiang University 1996/09 – 1999/06 Master's in Pharmacology: Zhejiang University 1989/09 – 1993/06 Bachelor's in Pharmacy: Zhejiang Medical University
Work Experience	2010/01 – Present - Zhejiang University - Associate Professor in Pharmacology 2007/01 – 2008/01 - Gifu Pharmaceutical University, Japan - Visiting Scholar 1999/08 – 2009/12 - Zhejiang University - Lecturer in Pharmacology
Awards	Zhejiang Provincial Teaching Achievement Award Second Prize (2016.11): Construction and operation of a comprehensive reform system for pharmacy professional based on the cultivation of innovative ability through the whole process modular practice Zhejiang University Teaching Achievement Award First Prize (2016.5): Construction and operation of a comprehensive reform system for pharmacy professional based on the cultivation of innovative ability through the whole process modular practice Zhejiang University Teaching Achievement Award Second Prize (2016.5): Construction and application of a multi-track teaching model for pharmacology courses oriented towards new drug development and rational drug use Zhejiang Provincial Teaching Achievement Award Second Prize (2014.9): Research on the reform of undergraduate pharmacy education aimed at self-learning and ability cultivation Zhejiang University Teaching Achievement Award First Prize (2012.9): Research on the reform of undergraduate pharmacy education aimed at self-learning and ability cultivation Zhejiang University Teaching Achievement Award First Prize (2012.9): Setting and practice of comprehensive design experiments in pharmacy

University/Lab Affiliation and Title

Zhejiang University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

2002/03 – 2006/12 PhD in Pharmacology: Zhejiang University
1996/09 – 1999/06 Master's in Pharmacology: Zhejiang University
1989/09 – 1993/06 Bachelor's in Pharmacy: Zhejiang Medical University

Work Experience

2010/01 – Present - Zhejiang University - Associate Professor in Pharmacology
2007/01 – 2008/01 - Gifu Pharmaceutical University, Japan - Visiting Scholar
1999/08 – 2009/12 - Zhejiang University - Lecturer in Pharmacology

Awards

Zhejiang Provincial Teaching Achievement Award Second Prize (2016.11): Construction and operation of a comprehensive reform system for pharmacy professional based on the cultivation of innovative ability through the whole process modular practice
Zhejiang University Teaching Achievement Award First Prize (2016.5): Construction and operation of a comprehensive reform system for pharmacy professional based on the cultivation of innovative ability through the whole process modular practice
Zhejiang University Teaching Achievement Award Second Prize (2016.5): Construction and application of a multi-track teaching model for pharmacology courses oriented towards new drug development and rational drug use
Zhejiang Provincial Teaching Achievement Award Second Prize (2014.9): Research on the reform of undergraduate pharmacy education aimed at self-learning and ability cultivation
Zhejiang University Teaching Achievement Award First Prize (2012.9): Research on the reform of undergraduate pharmacy education aimed at self-learning and ability cultivation
Zhejiang University Teaching Achievement Award First Prize (2012.9): Setting and practice of comprehensive design experiments in pharmacy

Areas of Focus	Pharmacology
Publications	Pharmaceutical Scientific Research Training: an early practice course for freshmen, Hao-Shu Wu, Ka-Lin Zhu, Xiao-Hui Fan & Jian-qing Gao, 2018 面向新药研发思维的药学本科生探究型实验教学, 吴昊姝、娄小娥、高建青、陆国栋, 2016 以学生小组合作式自主学习为中心的药理学小班化教学方法探索与实践, 吴昊姝、娄小娥、何俏军，杨波、丁玲, 2016 我国药学本科专业实践教学的现状分析与思考, 娄小娥、吴昊姝、杨波、何俏军, 2015 促进本科生自主学习的药物治疗学个性化教学方法探索, 吴昊姝、杨波、何俏军、朱虹、丁玲, 2013 提高认知、培养创新的药理学实验教学改革初探, 吴昊姝，何俏军，杨波, 2010 构建具有科研特色的药学实验教学新体系, 姚彤炜，胡永洲，袁弘，何俏军，刘滔，吴昊姝，陈柳蓉, 2010 Oleanolic acid derivative DKS26 exerts antidiabetic and hepatoprotective effects in diabetic mice and promotes glucagon-like peptide-1 secretion and expression in intestinal cells, Chen FF, Wang JT, Zhang LX, Xing SF, Wang YX, Wang K, Deng SL, Zhang JQ, Tang L, Wu HS, 2017 Neohesperidin Exerts Lipid-Regulating Effects in vitro and in vivo via Fibroblast Growth Factor 21 and AMP-Activated Protein Kinase/Sirtuin Type 1/Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α Signaling Axis, Wu HS, Liu YX, Chen XB, Zhu DF, Ma J, Yan YY, Si MM, Li X, Sun CD, Yang B, He QJ, Chen KS, 2017 Effects and molecular mechanisms of the antidiabetic fraction of Acorus calamus L. on GLP-1 expression and secretion in vivo and in vitro, Liu YX, Si MM, Lu W, Zhang LX, Zhou CX, Deng SL, Wu HS, 2015 A novel indole derivative compound GY3 improves glucose and lipid metabolism via activation of AMP-activated protein kinase pathway, Si M, Yan Y, Tang L, Wu H, Yang B, He Q, Wu H, 2013 Insulin releasing and Alpha-glucosidase inhibitory activity of ethyl acetate fraction of Acorus calamus in vitro and in vivo, Si MM, Lou JS, Zhou CX, Shen JN, Wu HH, Yang B, He QJ, Wu HS, 2010 Insulin sensitizing activity of ethyl acetate fraction of Acorus calamus L. in vitro and in vivo, Wu HS, Zhu DF, Zhou CX, Feng CR, Yang B, He QJ, Lou YJ, 2009 The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo, Li YY, Wu HS, Tang L, Feng CR, Yu JH, Li Y, Yang YS, Yang B, He QJ, 2007 A Fraction of Acorus calamus L. extract devoid of β-asarone enhances adipocyte differentiation in 3T3-L1 cells, Wu HS, Li YY, Weng LJ, Zhou CX, He QJ, Lou YJ, 2007 Insulin-sensitizing effects of a novel α-methyl-α-phenoxylpropionate derivative in vitro, Wu HS, Yu JH, Li YY, Yang YS, He QJ, Lou YJ, Ji RY, 2007 Design, synthesis, biological evaluation, and docking studies of (s)-phenylalanine derivatives with a 2-cyanopyrrolidine moiety as potent dipeptidyl peptidase 4 inhibitors, Liu Y, Wu Y, Wu H, Tang L, Wu P, Liu T, Hu Y, 2013 Design, synthesis and biological evaluation of novel imidazolone derivatives as dipeptidyl peptidase 4 inhibitors, Liu Y, Jiang C, Wu H, Wu P, Si M, Hu Y, Liu T, 2013 Synthesis and biological evaluation of novel benzyl-substituted (S)-phenylalanine derivatives as potent dipeptidyl peptidase 4 inhibitors, Liu Y, Si M, Tang L, Shangguan S, Wu H, Li J, Wu P, Ma X, Liu T, Hu Y, 2013 Insulin-releasing activity of a series of phenylalanine derivatives, Tang L, Yu JH, Wu HS, Fan HX, Yang YS, Ji RY, 2008 Design, synthesis and insulin-sensitizing activity of indomethacin and diclofenac derivatives, Zhang JQ, Wang JT, Wu HS, He YY, Zhu GF, Cui X, Tang L, 2009 Expression of extracellular-superoxide dismutase during adipose differentiation in 3T3-L1 cells, Adachi T, Toishi T, Wu HS, Kamiya T, Hara H, 2009 Design, synthesis and biological evaluation of GY3-based derivatives for anti-type 2 diabetes activity, Fan L, Wang J, Ma X, Xiao W, Li Z, Zhong G, Tang L, Wu H, 2015 Terpenoids from Curcuma wenyujin increased glucose consumption on HepG2 cells, Zhou CX, Zhang LS, Chen FF, Wu HS, Mo JX, Gan LS, 2017 A new anti-diabetic sesquiterpenoid from Acorus calamus, Zhou CX, Qiao D, Yan YY, Wu HS, Mo JX, Gan LS, 2012

Areas of Focus

Pharmacology

Publications

Pharmaceutical Scientific Research Training: an early practice course for freshmen, Hao-Shu Wu, Ka-Lin Zhu, Xiao-Hui Fan & Jian-qing Gao, 2018
面向新药研发思维的药学本科生探究型实验教学, 吴昊姝、娄小娥、高建青、陆国栋, 2016
以学生小组合作式自主学习为中心的药理学小班化教学方法探索与实践, 吴昊姝、娄小娥、何俏军，杨波、丁玲, 2016
我国药学本科专业实践教学的现状分析与思考, 娄小娥、吴昊姝、杨波、何俏军, 2015
促进本科生自主学习的药物治疗学个性化教学方法探索, 吴昊姝、杨波、何俏军、朱虹、丁玲, 2013
提高认知、培养创新的药理学实验教学改革初探, 吴昊姝，何俏军，杨波, 2010
构建具有科研特色的药学实验教学新体系, 姚彤炜，胡永洲，袁弘，何俏军，刘滔，吴昊姝，陈柳蓉, 2010
Oleanolic acid derivative DKS26 exerts antidiabetic and hepatoprotective effects in diabetic mice and promotes glucagon-like peptide-1 secretion and expression in intestinal cells, Chen FF, Wang JT, Zhang LX, Xing SF, Wang YX, Wang K, Deng SL, Zhang JQ, Tang L, Wu HS, 2017
Neohesperidin Exerts Lipid-Regulating Effects in vitro and in vivo via Fibroblast Growth Factor 21 and AMP-Activated Protein Kinase/Sirtuin Type 1/Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1α Signaling Axis, Wu HS, Liu YX, Chen XB, Zhu DF, Ma J, Yan YY, Si MM, Li X, Sun CD, Yang B, He QJ, Chen KS, 2017
Effects and molecular mechanisms of the antidiabetic fraction of Acorus calamus L. on GLP-1 expression and secretion in vivo and in vitro, Liu YX, Si MM, Lu W, Zhang LX, Zhou CX, Deng SL, Wu HS, 2015
A novel indole derivative compound GY3 improves glucose and lipid metabolism via activation of AMP-activated protein kinase pathway, Si M, Yan Y, Tang L, Wu H, Yang B, He Q, Wu H, 2013
Insulin releasing and Alpha-glucosidase inhibitory activity of ethyl acetate fraction of Acorus calamus in vitro and in vivo, Si MM, Lou JS, Zhou CX, Shen JN, Wu HH, Yang B, He QJ, Wu HS, 2010
Insulin sensitizing activity of ethyl acetate fraction of Acorus calamus L. in vitro and in vivo, Wu HS, Zhu DF, Zhou CX, Feng CR, Yang B, He QJ, Lou YJ, 2009
The potential insulin sensitizing and glucose lowering effects of a novel indole derivative in vitro and in vivo, Li YY, Wu HS, Tang L, Feng CR, Yu JH, Li Y, Yang YS, Yang B, He QJ, 2007
A Fraction of Acorus calamus L. extract devoid of β-asarone enhances adipocyte differentiation in 3T3-L1 cells, Wu HS, Li YY, Weng LJ, Zhou CX, He QJ, Lou YJ, 2007
Insulin-sensitizing effects of a novel α-methyl-α-phenoxylpropionate derivative in vitro, Wu HS, Yu JH, Li YY, Yang YS, He QJ, Lou YJ, Ji RY, 2007
Design, synthesis, biological evaluation, and docking studies of (s)-phenylalanine derivatives with a 2-cyanopyrrolidine moiety as potent dipeptidyl peptidase 4 inhibitors, Liu Y, Wu Y, Wu H, Tang L, Wu P, Liu T, Hu Y, 2013
Design, synthesis and biological evaluation of novel imidazolone derivatives as dipeptidyl peptidase 4 inhibitors, Liu Y, Jiang C, Wu H, Wu P, Si M, Hu Y, Liu T, 2013
Synthesis and biological evaluation of novel benzyl-substituted (S)-phenylalanine derivatives as potent dipeptidyl peptidase 4 inhibitors, Liu Y, Si M, Tang L, Shangguan S, Wu H, Li J, Wu P, Ma X, Liu T, Hu Y, 2013
Insulin-releasing activity of a series of phenylalanine derivatives, Tang L, Yu JH, Wu HS, Fan HX, Yang YS, Ji RY, 2008
Design, synthesis and insulin-sensitizing activity of indomethacin and diclofenac derivatives, Zhang JQ, Wang JT, Wu HS, He YY, Zhu GF, Cui X, Tang L, 2009
Expression of extracellular-superoxide dismutase during adipose differentiation in 3T3-L1 cells, Adachi T, Toishi T, Wu HS, Kamiya T, Hara H, 2009
Design, synthesis and biological evaluation of GY3-based derivatives for anti-type 2 diabetes activity, Fan L, Wang J, Ma X, Xiao W, Li Z, Zhong G, Tang L, Wu H, 2015
Terpenoids from Curcuma wenyujin increased glucose consumption on HepG2 cells, Zhou CX, Zhang LS, Chen FF, Wu HS, Mo JX, Gan LS, 2017
A new anti-diabetic sesquiterpenoid from Acorus calamus, Zhou CX, Qiao D, Yan YY, Wu HS, Mo JX, Gan LS, 2012

Pharmacology Drug Development Therapeutics Pharmaceutical Education Innovative Teaching Research Training Diabetes Lipid Metabolism Insulin Sensitization Glp-1

Hongbo Weng - Fudan University

Zhiruo Zhou - Fudan University

Xin Hong - Fudan University

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