Professor | Lei Liang | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Lei Liang
Contact Information	leiliang@bjmu.edu.cn
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Lei Liang

Contact Information

leiliang@bjmu.edu.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Pharmaceutical Sciences
Academic Background & Achievements	2000.9-2004.7 Bachelor of Science: Sichuan University, College of Chemistry 2004.9-2009.7 Joint Ph.D.: Sichuan University & University of Illinois at Urbana-Champaign
Work Experience	2009.7-2011.6 - Peking University, College of Chemistry and Molecular Engineering - Postdoctoral Researcher 2011.7-2014.7 - Peking University, School of Pharmaceutical Sciences - Lecturer 2014.8-Present - Peking University, School of Pharmaceutical Sciences - Associate Professor, Master's Supervisor 2018.10-2019.10 - Stanford University, School of Medicine - Visiting Scholar
Awards	2012 - First Prize in Young Teacher Teaching Demonstration Competition, School of Pharmaceutical Sciences, Peking University 2012 - Second Prize in the 12th Young Teacher Teaching Demonstration Competition, Peking University 2016 - First Prize in Young Teacher Teaching Demonstration Competition, School of Pharmaceutical Sciences, Peking University

University/Lab Affiliation and Title

Peking University

Faculty

Pharmaceutical Sciences

Academic Background & Achievements

2000.9-2004.7 Bachelor of Science: Sichuan University, College of Chemistry
2004.9-2009.7 Joint Ph.D.: Sichuan University & University of Illinois at Urbana-Champaign

Work Experience

2009.7-2011.6 - Peking University, College of Chemistry and Molecular Engineering - Postdoctoral Researcher
2011.7-2014.7 - Peking University, School of Pharmaceutical Sciences - Lecturer
2014.8-Present - Peking University, School of Pharmaceutical Sciences - Associate Professor, Master's Supervisor
2018.10-2019.10 - Stanford University, School of Medicine - Visiting Scholar

Awards

2012 - First Prize in Young Teacher Teaching Demonstration Competition, School of Pharmaceutical Sciences, Peking University
2012 - Second Prize in the 12th Young Teacher Teaching Demonstration Competition, Peking University
2016 - First Prize in Young Teacher Teaching Demonstration Competition, School of Pharmaceutical Sciences, Peking University

Areas of Focus	Design of molecular probes and their application in early disease diagnosis Construction of fluorescent probes based on protein structure and discovery of active substances in traditional Chinese medicine Drug design, synthesis, and structure-activity relationship studies
Publications	A Smart Fluorescent Probe for NO Detection and Application in Myocardial Fibrosis Imaging, Tongliang Zhou, Junda Wang, Jiamin Xu, Cangxin Zheng, Yan Niu, Chao Wang, Fengrong Xu, Lan Yuan, Xin Zhao, Lei Liang, Ping Xu, 2020 Design, synthesis and biological evaluation of cobalt(II)-Schi base complexes as ATP-noncompetitive MEK1 inhibitors, Hongyue Li, Dandan Xi, Yan Niu, Chao Wang, Fengrong Xu, Lei Liang, Ping Xu, 2019 Rational Design of a Near-infrared Fluorescent Probe Based on Pyridazinone Scaffold, Tongliang Zhou, Lingfei Yang, Lei Liang, Hui Liu, Yuanjun Zhu, Mengyang Shui, Lan Yuan, Fengrong Xu, Yan Niu, Chao Wang, Ping Xu, 2017 Revelation of the dynamic progression of hypoxia-reoxygenation injury by visualization of the lysosomal hydrogen peroxide, Yuanjun Zhu, Tongliang Zhou, Lingfei Yang, Lan Yuan, Lei Liang, Ping Xu, 2017 Discovery of a cobalt complex with high MEK1 binding affinity, Hongyue Li, Tongliang Zhou, Hui Liu, Fengrong Xu, Yan Niu, Chao Wang, Lei Liang, Ping Xu, 2017 Discovery of a potent and highly specific beta(2) proteasome inhibitor from a library of copper complexes, Tongliang Zhou, Yuanbo Cai, Lei Liang, Lingfei Yang, Fengrong Xu, Yan Niu, Chao Wang, Junlong Zhang, Ping Xu, 2016 Rational design of fluorescent phthalazinone derivatives for one- and two-photon imaging, Lingfei Yang, Yuanjun Zhu, Mengyang Shui, Tongliang Zhou, Yuanbo Cai, Wei Wang, Fengrong Xu, Yan Niu, Chao Wang, Jun-Long Zhang, Ping Xu, Lan Yuan, Lei Liang, 2016 Development of novel proteasome inhibitors based on phthalazinone scaffold, Lingfei Yang, Wei Wang, Qi Sun, Fengrong Xu, Yan Niu, Chao Wang, Lei Liang, Ping Xu, 2016 Ruthenium-Catalyzed Switchable N–H/C–H Alkenylation of 6-Phenyl(dihydro)pyridazinones with Alkynes, Wei Wang, Lei Liang, Fengrong Xu, Wenjie Huang, Yan Niu, Qi Sun, Ping Xu, 2014 Rational Design, Green Synthesis, and Initial Evaluation of a Series of Full-Color Tunable Fluorescent Dyes Enabled by the Copper-Catalyzed N-Arylation of 6-Phenyl Pyridazinones and Their Application in Cell Imaging, Lei Liang, Wei Wang, Jun Wu, Fengrong Xu, Yan Niu, Bo Xu, Ping Xu, 2013 Relay Catalysis by a Multifunctional Cu Catalyst in a Tandem Dehydro-/Dehalogenation Sequence along with N-Arylation, Lei Liang, Wei Wang, Fengrong Xu, Yan Niu, Qi Sun, Ping Xu, 2013 A Copper-Catalyzed Aerobic Cascade Dehydrogenative Dehalogenative Reaction, Lei Liang, Guanyu Yang, Fengrong Xu, Yan Niu, Qi Sun, Ping Xu, 2013 Copper-Catalyzed Aerobic Dehydrogenation of C–C to C=C Bonds in the Synthesis of Pyridazinones, Lei Liang, Guanyu Yang, Fengrong Xu, Yan Niu, Qi Sun, Ping Xu, 2013

Areas of Focus

Design of molecular probes and their application in early disease diagnosis
Construction of fluorescent probes based on protein structure and discovery of active substances in traditional Chinese medicine
Drug design, synthesis, and structure-activity relationship studies

Publications

A Smart Fluorescent Probe for NO Detection and Application in Myocardial Fibrosis Imaging, Tongliang Zhou, Junda Wang, Jiamin Xu, Cangxin Zheng, Yan Niu, Chao Wang, Fengrong Xu, Lan Yuan, Xin Zhao, Lei Liang, Ping Xu, 2020
Design, synthesis and biological evaluation of cobalt(II)-Schi base complexes as ATP-noncompetitive MEK1 inhibitors, Hongyue Li, Dandan Xi, Yan Niu, Chao Wang, Fengrong Xu, Lei Liang, Ping Xu, 2019
Rational Design of a Near-infrared Fluorescent Probe Based on Pyridazinone Scaffold, Tongliang Zhou, Lingfei Yang, Lei Liang, Hui Liu, Yuanjun Zhu, Mengyang Shui, Lan Yuan, Fengrong Xu, Yan Niu, Chao Wang, Ping Xu, 2017
Revelation of the dynamic progression of hypoxia-reoxygenation injury by visualization of the lysosomal hydrogen peroxide, Yuanjun Zhu, Tongliang Zhou, Lingfei Yang, Lan Yuan, Lei Liang, Ping Xu, 2017
Discovery of a cobalt complex with high MEK1 binding affinity, Hongyue Li, Tongliang Zhou, Hui Liu, Fengrong Xu, Yan Niu, Chao Wang, Lei Liang, Ping Xu, 2017
Discovery of a potent and highly specific beta(2) proteasome inhibitor from a library of copper complexes, Tongliang Zhou, Yuanbo Cai, Lei Liang, Lingfei Yang, Fengrong Xu, Yan Niu, Chao Wang, Junlong Zhang, Ping Xu, 2016
Rational design of fluorescent phthalazinone derivatives for one- and two-photon imaging, Lingfei Yang, Yuanjun Zhu, Mengyang Shui, Tongliang Zhou, Yuanbo Cai, Wei Wang, Fengrong Xu, Yan Niu, Chao Wang, Jun-Long Zhang, Ping Xu, Lan Yuan, Lei Liang, 2016
Development of novel proteasome inhibitors based on phthalazinone scaffold, Lingfei Yang, Wei Wang, Qi Sun, Fengrong Xu, Yan Niu, Chao Wang, Lei Liang, Ping Xu, 2016
Ruthenium-Catalyzed Switchable N–H/C–H Alkenylation of 6-Phenyl(dihydro)pyridazinones with Alkynes, Wei Wang, Lei Liang, Fengrong Xu, Wenjie Huang, Yan Niu, Qi Sun, Ping Xu, 2014
Rational Design, Green Synthesis, and Initial Evaluation of a Series of Full-Color Tunable Fluorescent Dyes Enabled by the Copper-Catalyzed N-Arylation of 6-Phenyl Pyridazinones and Their Application in Cell Imaging, Lei Liang, Wei Wang, Jun Wu, Fengrong Xu, Yan Niu, Bo Xu, Ping Xu, 2013
Relay Catalysis by a Multifunctional Cu Catalyst in a Tandem Dehydro-/Dehalogenation Sequence along with N-Arylation, Lei Liang, Wei Wang, Fengrong Xu, Yan Niu, Qi Sun, Ping Xu, 2013
A Copper-Catalyzed Aerobic Cascade Dehydrogenative Dehalogenative Reaction, Lei Liang, Guanyu Yang, Fengrong Xu, Yan Niu, Qi Sun, Ping Xu, 2013
Copper-Catalyzed Aerobic Dehydrogenation of C–C to C=C Bonds in the Synthesis of Pyridazinones, Lei Liang, Guanyu Yang, Fengrong Xu, Yan Niu, Qi Sun, Ping Xu, 2013

Molecular Probes Early Disease Diagnosis Fluorescent Probes Protein Structure Traditional Chinese Medicine Drug Design Synthesis Structure-Activity Relationship Biological Evaluation Imaging

Lu Zhou - Fudan University

Liming Shao - Fudan University

Qian Zhang - Fudan University

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us