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Xiuqin Zhang
Life Sciences / Medical / Biology
Peking University
Beijing
Language: Chinese, Japanese, English
Metabolic Diseases
Cardiovascular Diseases
Animal Models
Primates
Obesity
Fatty Liver
Type 2 Diabetes
Pathogenesis
Pharmacodynamics
Preclinical Research
Areas of Focus
- Establishment and research of animal models for metabolic and cardiovascular diseases in primates
- Pathogenesis research of obesity, fatty liver, and type 2 diabetes using primate and rodent models
- Preclinical pharmacodynamic research using primate models
Work Experience
- 1995.7-1996.6 - Fuwai Hospital, Chinese Academy of Medical Sciences - Resident Physician
- 1996.7-1997.3 - Kumamoto University School of Medicine - Visiting Researcher
- 1997.4-1998.3 - Kumamoto University School of Medicine - Special Researcher, Ministry of Education, Japan (Part-time Lecturer)
- 2002.4-2006.3 - Washington University School of Medicine - Postdoctoral Fellow
- 2006.4-2013.8 - Peking University Institute of Molecular Medicine - Associate Researcher
- 2013.9 - Present - Peking University Academy for Advanced Interdisciplinary Studies - Researcher
Academic Background & Achievements
- 1992-1995 Master's Degree: China Medical University, Supervisor: Zongxuan Li
- 1998-2002 Doctoral Degree: Kumamoto University School of Medicine, Supervisor: Toshio Suda
Publications
- A chemical approach for global protein knockdown from mice to non-human primates, Sun X, Wang J, Yao X, Zheng W, Mao Y, Lan T, Wang L, Sun Y, Zhang X, Zhao Q, Zhao J, Xiao RP, Zhang X*, Ji G*, Rao Y*, 2019
- Dynamic changes in insulin and glucagon during disease progression in rhesus monkeys with obesity-related type 2 diabetes mellitus, Wang C, Xiao Y, Wang J, Hou N, Cui W, Hu X, Zeng F, Yuan Y, Ma D, Sun X, Zhang Y, Zheng W, Liu Y, Shang H, Chen L, Xiao RP, Zhang X*, 2019
- Central role of RIPK1-VDAC1 pathway on cardiac impairment in a non-human primate model of rheumatoid arthritis, Zeng F, Wen W, Cui W, Zheng W, Liu Y, Sun X, Hou N, Ma D, Yuan Y, Shi H, Wang Z, Li Z, Xiao Y, Wang C, Li Y, Shang H, Li C, Wang J, Zhang Y, Xiao RP, Zhang X*, 2018
- Characterization of spontaneously-developed non-alcoholic fatty liver disease in aged rhesus monkeys, Zheng W, Liu Y, Shang H, Zhang Y, Ma D, Hou N, Wang J, Sun X, Peng Y, Pan L, Wang Z, Tang X, Xiao RP, Zhang X*, 2018
- Deficiency of PRKD2 triggers hyperinsulinemia and metabolic disorders, Xiao Y, Wang C, Chen JY, Lu F, Wang J, Hou N, Hu X, Zeng F, Ma D, Sun X, Ding Y, Zhang Y, Zheng W, Liu Y, Shang H, Zhu W, Han C, Zhang Y, Ouyang K, Chen L, Chen J, Xiao RP, Li CY, Zhang X*, 2018
- RIPK1 Binds MCU to Mediate Induction of Mitochondrial Ca2+ Uptake and Promotes Colorectal Oncogenesis, Zeng F, Chen X, Cui W, Wen W, Lu F, Sun X, Ma D, Yuan Y, Li Z, Hou N, Zhao H, Bi X, Zhao J, Zhou J, Zhang Y, Xiao RP, Cai J, Zhang X*, 2018
- Eplerenone restores 24-h blood pressure circadian rhythm and reduces advanced glycation end-products in rhesus macaques with spontaneous hypertensive metabolic syndrome, Zhang Y, Zheng W, Liu Y, Wang J, Peng Y, Shang H, Hou N, Hu X, Ding Y, Xiao Y, Wang C, Zeng F, Mao J, Zhang J, Ma D, Sun X, Li C, Xiao RP, Zhang X*, 2016
