Professor | Zhuqing Zhang | Asia Growth Partners

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Name	Zhuqing Zhang
Contact Information	zhuqingzhang@ucas.ac.cn
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Zhuqing Zhang

Contact Information

zhuqingzhang@ucas.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Work Experience	2005-2007 - Peking University, College of Chemistry and Molecular Engineering, Center for Theoretical Biology - Postdoctoral Researcher 2008-2011 - University of Toronto, Department of Biochemistry, Faculty of Medicine - Postdoctoral Researcher 2011.6-Present - University of Chinese Academy of Sciences, School of Life Sciences - Associate Professor, Professor

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Work Experience

2005-2007 - Peking University, College of Chemistry and Molecular Engineering, Center for Theoretical Biology - Postdoctoral Researcher
2008-2011 - University of Toronto, Department of Biochemistry, Faculty of Medicine - Postdoctoral Researcher
2011.6-Present - University of Chinese Academy of Sciences, School of Life Sciences - Associate Professor, Professor

Areas of Focus	Simulation and computation related to conformational changes of biological macromolecules Protein folding and allosteric mechanisms Structural characteristics and functional relationships of intrinsically disordered proteins Mechanisms of phase separation in protein systems
Publications	Evaluation of sequences-based predictors for phase separating protein, Shaofeng Liao, Yujun Zhang, Yifei Qi, Zhuqing Zhang, 2023 Prediction of liquid-liquid phase separating proteins using machine learning, Xiaoquan Chu†, Tanlin Sun†, Qian Li, Youjun Xu, Zhuqing Zhang, Luhua Lai, Jianfeng Pei, 2022 LLPSDB v2.0: an updated database of proteins undergoing liquid-liquid phase separation in vitro, Xi Wang†, Xiang Zhou†, Qinglin Yan†, Shaofeng Liao, Wenqin Tang, Peiyu Xu, Yangzhenyu Gao, Qian Li, Zhihui Dou, Weishan Yang, Beifang Huang, Jinhong Li, Zhuqing Zhang, 2022 LLPSDB: a database of proteins undergoing liquid–liquid phase separation in vitro, Qian Li†, Xiaojun Peng†, Yuanqing Li, Wenqin Tang, Jia'an Zhu, Jing Huang, Yifei Qi and Zhuqing Zhang, 2020 How calcium ion binding induces the conformational transition of the calmodulin N-terminal domain-an atomic level characterization, Likun Zhao, Luhua Lai, Zhuqing Zhang, 2019 Characterization of the structural ensembles of p53 TAD2 by molecular dynamics simulations with different force fields, Yanhua Ouyang, Likun Zhao, Zhuqing Zhang, 2018 A critical comparison of coarse-grained structure-based approaches and atomic models of protein folding, Jie Hu, Tao Chen, Moye Wang, Hue Sun Chan, Zhuqing Zhang, 2017 Influences of heterogeneous native contact energy and many-body interactions on the prediction of protein folding mechanisms, Zhuqing Zhang, Yanhua Ouyang, Tao Chen, 2016 Transition paths, diffusive processes, and preequilibria of protein folding, Zhuqing Zhang, and Hue Sun Chan, 2012 Native Topology, Local-Nonlocal Coupling, and Nonnative Interactions: Principles of Protein Folding from Coarse-Grained Models, Hue Sun Chan, Zhuqing Zhang, Stefan Wallin and Zhirong Liu, 2011 Competition between Native Topology and Nonnative Interactions in Simple and Complex Folding Kinetics of Natural and Designed Proteins, Zhuqing Zhang, and Hue Sun Chan, 2010 Identification of amyloid fibril-forming segments based on structure and residue-based statistical potential, Zhuqing Zhang, Hao Chen, Luhua Lai, 2007 Molecular dynamics simulations on the oligomer formation process of the GNNQQNY peptide from yeast prion protein Sup35, Zhuqing Zhang, Hao Chen, Hongjun Bai, Luhua Lai, 2007

Areas of Focus

Simulation and computation related to conformational changes of biological macromolecules
Protein folding and allosteric mechanisms
Structural characteristics and functional relationships of intrinsically disordered proteins
Mechanisms of phase separation in protein systems

Publications

Evaluation of sequences-based predictors for phase separating protein, Shaofeng Liao, Yujun Zhang, Yifei Qi*, Zhuqing Zhang*, 2023
Prediction of liquid-liquid phase separating proteins using machine learning, Xiaoquan Chu†, Tanlin Sun†, Qian Li, Youjun Xu, Zhuqing Zhang*, Luhua Lai*, Jianfeng Pei*, 2022
LLPSDB v2.0: an updated database of proteins undergoing liquid-liquid phase separation in vitro, Xi Wang†, Xiang Zhou†, Qinglin Yan†, Shaofeng Liao, Wenqin Tang, Peiyu Xu, Yangzhenyu Gao, Qian Li, Zhihui Dou, Weishan Yang, Beifang Huang, Jinhong Li, Zhuqing Zhang*, 2022
LLPSDB: a database of proteins undergoing liquid–liquid phase separation in vitro, Qian Li†, Xiaojun Peng†, Yuanqing Li, Wenqin Tang, Jia'an Zhu, Jing Huang, Yifei Qi and Zhuqing Zhang*, 2020
How calcium ion binding induces the conformational transition of the calmodulin N-terminal domain-an atomic level characterization, Likun Zhao, Luhua Lai*, Zhuqing Zhang*, 2019
Characterization of the structural ensembles of p53 TAD2 by molecular dynamics simulations with different force fields, Yanhua Ouyang, Likun Zhao, Zhuqing Zhang*, 2018
A critical comparison of coarse-grained structure-based approaches and atomic models of protein folding, Jie Hu, Tao Chen, Moye Wang, Hue Sun Chan*, Zhuqing Zhang*, 2017
Influences of heterogeneous native contact energy and many-body interactions on the prediction of protein folding mechanisms, Zhuqing Zhang*, Yanhua Ouyang, Tao Chen, 2016
Transition paths, diffusive processes, and preequilibria of protein folding, Zhuqing Zhang, and Hue Sun Chan*, 2012
Native Topology, Local-Nonlocal Coupling, and Nonnative Interactions: Principles of Protein Folding from Coarse-Grained Models, Hue Sun Chan*, Zhuqing Zhang, Stefan Wallin and Zhirong Liu, 2011
Competition between Native Topology and Nonnative Interactions in Simple and Complex Folding Kinetics of Natural and Designed Proteins, Zhuqing Zhang, and Hue Sun Chan*, 2010
Identification of amyloid fibril-forming segments based on structure and residue-based statistical potential, Zhuqing Zhang, Hao Chen, Luhua Lai*, 2007
Molecular dynamics simulations on the oligomer formation process of the GNNQQNY peptide from yeast prion protein Sup35, Zhuqing Zhang, Hao Chen, Hongjun Bai, Luhua Lai*, 2007

Simulation Computation Conformational Changes Biological Macromolecules Protein Folding Allosteric Mechanisms Intrinsically Disordered Proteins Structural Characteristics Functional Relationships Phase Separation

Zhuqing Zhang - University of Chinese Academy of Sciences

Haipeng Gong - Tsinghua University

Yi Xue - Tsinghua University

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