Upload Avatar (500 x 500)
Changhao Bi
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: Chinese, English
Synthetic Biology
Genome Editing
Crispr
Metabolic Engineering
Gene Editing
Biotechnology
Cell Design
Artificial Cells
Cell Machines
Genetic Engineering
Areas of Focus
- Synthetic Biology
- Genome Editing Technology
Work Experience
- 2014-01~Present - Chinese Academy of Sciences, Tianjin Institute of Industrial Biotechnology - Researcher, Professor
- 2011-09~Present - Lawrence Berkeley National Laboratory - Junior Researcher
- 2009-09~Present - University of Delaware - Postdoctoral Researcher
Academic Background & Achievements
- 2004-08 - Ph.D.: University of Florida
- 2001-09 - Master's: Nankai University
- 1997-09 - Bachelor's: Nankai University
Publications
- Glycosylase base editors enable C-to-A and C-to-G base changes, Zhao D., Li J., Li S., Xin, X., Hu M., Price M., Rosser S., Bi, C.* & Zhang, X.*, 2020
- CRISPR-based metabolic pathway engineering, Zhao D, Zhu X, Zhou H, Sun N, Wang T, Bi, C.* & Zhang, X.*, 2020
- Identification of Absidia orchidis steroid 11β-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone, Chen J, Fan F, Qu G, Tang J, Xi Y, Bi C, Sun Z, Zhang X*, 2020
- Construction of a carbon-conserving pathway for glycolate production by synergetic utilization of acetate and glucose in Escherichia coli, Yu Y, Shao M, Li D, Fan F, Xu H, Lu F, Bi C, Zhu X, Zhang X, 2020
- A programmable CRISPR/Cas9-based phage defense system for Escherichia coli BL21(DE3), Liu L, Zhao D, Ye L, Zhan T, Xiong B, Hu M, Bi, C.* & Zhang, X.*, 2020
- Engineering the Calvin-Benson-Bassham cycle and hydrogen utilization pathway of Ralstonia eutropha for improved autotrophic growth and polyhydroxybutyrate production, Li Z, Xin X, Xiong B, Zhao D, Zhang X*, Bi C*, 2020
- Manipulating the position of DNA expression cassettes using location tags fused to dCas9 (Cas9-Lag) to improve metabolic pathway efficiency, Xie Q, Li S, Zhao D, Ye L, Li Q, Zhang X, Zhu L*, Bi C*, 2020
- Constructing a Novel Biosynthetic Pathway for the Production of Glycolate from Glycerol in Escherichia coli, Zhan T, Chen Q, Zhang C, Bi, C.* & Zhang, X.*, 2020
- Coordinated Expression of Astaxanthin Biosynthesis Genes for Improved Astaxanthin Production in Escherichia coli, Gong Z, Wang H, Tang J, Bi C, Li Q, Zhang X, 2020
- CRISPR-dCas9 Mediated Cytosine Deaminase Base Editing in Bacillus subtilis, Yu S, Price M., Wang Y, Rosser S., Bi, C.*, and Wang M.*, 2020
Awards
- Presidential Scholarship, First Prize, Institute Level, 2005
