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毕昌昊
Life Science
中国科学院大学
天津
Language: 中文, 英语
合成生物学
基因组编辑
Crispr
代谢工程
基因编辑
生物技术
细胞设计
人工细胞
细胞机器
基因工程
Areas of Focus
- 合成生物学
- 基因组编辑技术
Work Experience
- 2014-01~现在 - 中国科学院天津工业生物技术研究所 - 研究员、教授
- 2011-09~现在 - 美国劳伦斯伯克利国家实验室 - 青年研究员
- 2009-09~现在 - 美国特拉华大学 - 博士后研究员
Academic Background & Achievements
- 2004-08 - 博士: 弗罗里达大学
- 2001-09 - 硕士: 南开大学
- 1997-09 - 学士: 南开大学
Publications
- Glycosylase base editors enable C-to-A and C-to-G base changes, Zhao D., Li J., Li S., Xin, X., Hu M., Price M., Rosser S., Bi, C.* & Zhang, X.*, 2020
- CRISPR-based metabolic pathway engineering, Zhao D, Zhu X, Zhou H, Sun N, Wang T, Bi, C.* & Zhang, X.*, 2020
- Identification of Absidia orchidis steroid 11β-hydroxylation system and its application in engineering Saccharomyces cerevisiae for one-step biotransformation to produce hydrocortisone, Chen J, Fan F, Qu G, Tang J, Xi Y, Bi C, Sun Z, Zhang X*, 2020
- Construction of a carbon-conserving pathway for glycolate production by synergetic utilization of acetate and glucose in Escherichia coli, Yu Y, Shao M, Li D, Fan F, Xu H, Lu F, Bi C, Zhu X, Zhang X, 2020
- A programmable CRISPR/Cas9-based phage defense system for Escherichia coli BL21(DE3), Liu L, Zhao D, Ye L, Zhan T, Xiong B, Hu M, Bi, C.* & Zhang, X.*, 2020
- Engineering the Calvin-Benson-Bassham cycle and hydrogen utilization pathway of Ralstonia eutropha for improved autotrophic growth and polyhydroxybutyrate production, Li Z, Xin X, Xiong B, Zhao D, Zhang X*, Bi C*, 2020
- Manipulating the position of DNA expression cassettes using location tags fused to dCas9 (Cas9-Lag) to improve metabolic pathway efficiency, Xie Q, Li S, Zhao D, Ye L, Li Q, Zhang X, Zhu L*, Bi C*, 2020
- Constructing a Novel Biosynthetic Pathway for the Production of Glycolate from Glycerol in Escherichia coli, Zhan T, Chen Q, Zhang C, Bi, C.* & Zhang, X.*, 2020
- Coordinated Expression of Astaxanthin Biosynthesis Genes for Improved Astaxanthin Production in Escherichia coli, Gong Z, Wang H, Tang J, Bi C, Li Q, Zhang X, 2020
- CRISPR-dCas9 Mediated Cytosine Deaminase Base Editing in Bacillus subtilis, Yu S, Price M., Wang Y, Rosser S., Bi, C.*, and Wang M.*, 2020
Awards
- 总统奖学金，一等奖，研究所（学校）级，2005
