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Yuewen Chen
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Neurodevelopment
Molecular Basis
Cellular Basis
Neurodevelopmental Disorders
Pathogenesis
Neuroscience
Neurobiology
Neurogenesis
Neurodegeneration
Brain Development
Areas of Focus
- Molecular and cellular basis of neurodevelopment
- Pathogenesis of neurodevelopmental disorders
Work Experience
- 2017-03 to Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
- 2014-12 to 2017-02 - Shenzhen Research Institute, Hong Kong University of Science and Technology - Research and Project Development Manager
- 2012-07 to 2014-11 - Jinan University - Postdoctoral Researcher
- 2009-01 to 2009-08 - Peking Union Medical College - Research Assistant
Academic Background & Achievements
- 2009-09 to 2012-06 PhD: Jinan University
- 2005-09 to 2008-12 Master's Degree: Peking Union Medical College
- 2001-09 to 2005-07 Bachelor's Degree: Lanzhou University
Publications
- Astrocyte-mediated regulation of BLAWFS1 neurons alleviates risk-assessment deficits in DISC1-N mice, Not mentioned, 2024
- Gut microbiota-driven metabolic alterations reveal gut-brain communication in Alzheimer’s disease model mice, Not mentioned, 2024
- Unlocking the Therapeutic Potential of Exosomes Derived From Nasal Olfactory Mucosal Mesenchymal Stem Cells: Restoring Synaptic Plasticity, Neurogenesis, and Neuroinflammation in Schizophrenia, Not mentioned, 2023
- Music prevents stress-induced depression and anxiety-like behavior in mice, Not mentioned, 2023
- Coronin 2B Regulates Neuronal Migration via Rac1-Dependent Multipolar-Bipolar Transition, Not mentioned, 2023
- Dynamic network modeling of gut microbiota during Alzheimer's disease progression in mice, Not mentioned, 2023
- Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction, Not mentioned, 2023
- Generation of a homozygous ABCA7-knockout human iPSC line using the CRISPR/Cas9 system, Not mentioned, 2023
- Identification of serum exosomal metabolomic and proteomic profiles for remote ischemic preconditioning, Not mentioned, 2023
- An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE -ε4 in female patients with Alzheimer's disease, Not mentioned, 2022
- Association of SPI1 Haplotypes with Altered SPI1 Gene Expression and Alzheimer's Disease Risk, Not mentioned, 2022
- Early Changes in Transcriptomic Profiles in Synaptodendrosomes Reveal Aberrant Synaptic Functions in Alzheimer's Disease, Not mentioned, 2022
- Brain-wide Cas9-mediated cleavage of a gene causing familial Alzheimer's disease alleviates amyloid-related pathologies in mice, Not mentioned, 2022
- Efficient manipulation of gene dosage in human iPSCs using CRISPR/Cas9 nickases, Not mentioned, 2021
- EphB2 activates CREB-dependent expression of Annexin A1 to regulate dendritic spine morphogenesis, Not mentioned, 2021
- Coronin 2B regulates dendrite outgrowth by modulating actin dynamics, Not mentioned, 2020
- p39-associated Cdk5 activity regulates dendritic morphogenesis, Not mentioned, 2020
- Gut Microbiome Alterations Precede Cerebral Amyloidosis and Microglial Pathology in a Mouse Model of Alzheimer's Disease, Not mentioned, 2020
- Genetic and polygenic risk score analysis for Alzheimer's disease in the Chinese population, Not mentioned, 2020
- Non-coding variability at the APOE locus contributes to the Alzheimer’s risk, Not mentioned, 2019
- Spatiotemporal Regulation of Rho GTPases in Neuronal Migration, Not mentioned, 2019
- Changes of Protein Phosphorylation Are Associated with Synaptic Functions during the Early Stage of Alzheimer's Disease, Not mentioned, 2019
- Identification of genetic risk factors in the Chinese population implicates a role of immune system in Alzheimer's disease pathogenesis., Not mentioned, 2018
- Axin Regulates Dendritic Spine Morphogenesis through Cdc42-Dependent Signaling, Not mentioned, 2015
- Coronin 6 Regulates Acetylcholine Receptor Clustering through Modulating Receptor Anchorage to Actin Cytoskeleton, Not mentioned, 2014
- The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics, Not mentioned, 2013
- Olean-12-Eno2,3-c 1,2,5Oxadiazol-28-Oic Acid (OEOA) Induces G 1 Cell Cycle Arrest and Differentiation in Human Leukemia Cell Lines, Not mentioned, 2013
- Identification of TNIP1 Polymorphisms by High Resolution Melting Analysis with Unlabelled Probe: Association with Systemic Lupus Erythematosus, Not mentioned, 2012
- The association between single-nucleotide polymorphisms of NCF2 and systemic lupus erythematosus in Chinese mainland population, Not mentioned, 2011
- Myostatin regulates glucose metabolism via the AMP-activated protein kinase pathway in skeletal muscle cells, Not mentioned, 2010
- Upregulation of myostatin gene expression in streptozotocin-induced type 1 diabetes mice is attenuated by insulin, Not mentioned, 2009
- BS69 undergoes SUMO modification and plays an inhibitory role in muscle and neuronal differentiation, Not mentioned, 2009
- The Atypical Guanine Nucleotide Exchange Factor Dock4 Regulates Neurite Differentiation through Modulation of Rac1 GTPase and Actin Dynamics, Not mentioned
- SCIENTIFIC REPORTS, Not mentioned
