Professor | Yan Song | Asia Growth Partners

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Name	Yan Song
Contact Information	yan.song@pku.edu.cn
Language ability	English, Chinese
Province	Beijing

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Name

Yan Song

Contact Information

yan.song@pku.edu.cn

Language ability

English, Chinese

Province

Beijing

University/Lab Affiliation and Title	Peking University
Faculty	Life Sciences
Academic Background & Achievements	2001-2006 PhD in Molecular Genetics, Duke University 1996-2000 Bachelor of Science in Cell Genetics, Peking University
Work Experience	2023-Present Vice Dean (Undergraduate Teaching), School of Life Sciences, Peking University 2013-Present Researcher, School of Life Sciences, Peking University 2019-Present Researcher, Peking University-Tsinghua University Center for Life Sciences (CLS) 2013-2018 Young Scholar, Peking University-Tsinghua University Center for Life Sciences (CLS) 2011-2012 Associate Researcher, Department of Pathology, Stanford University 2006-2011 Postdoctoral Fellow, Department of Pathology, Stanford University
Awards	2024 Peking University Outstanding Undergraduate Thesis Advisor Award 2023 Most Popular Teacher Award, School of Life Sciences, Peking University 2023 Peking University Teaching Excellence Award 2023 Peking University 'Model Class Collective' Class Teacher 2022 Ministry of Education Top Student Training Program 2.0 Outstanding Teacher Award 2022 Peking University Outstanding Undergraduate Research Training Advisor Award 2021 Invited Speaker Award at the 3rd Young Frontiers Forum in Neurocell Biology 2019 Elected to the Early Career Advisory Board of the Journal of Cell Biology 2016 Most Popular Teacher Award, School of Life Sciences, Peking University 2015 Second Prize in Peking University Young Teacher Teaching Skills Competition 2015 Peking University Teaching Excellence Award 2006 Stanford University Medical School Dean's Postdoctoral Fellowship, USA 2005 Keystone Symposium Abstract Award, USA 2002-2006 Howard Hughes Medical Institute (HHMI) PhD Scholarship, USA

University/Lab Affiliation and Title

Peking University

Faculty

Life Sciences

Academic Background & Achievements

2001-2006 PhD in Molecular Genetics, Duke University
1996-2000 Bachelor of Science in Cell Genetics, Peking University

Work Experience

2023-Present Vice Dean (Undergraduate Teaching), School of Life Sciences, Peking University
2013-Present Researcher, School of Life Sciences, Peking University
2019-Present Researcher, Peking University-Tsinghua University Center for Life Sciences (CLS)
2013-2018 Young Scholar, Peking University-Tsinghua University Center for Life Sciences (CLS)
2011-2012 Associate Researcher, Department of Pathology, Stanford University
2006-2011 Postdoctoral Fellow, Department of Pathology, Stanford University

Awards

2024 Peking University Outstanding Undergraduate Thesis Advisor Award
2023 Most Popular Teacher Award, School of Life Sciences, Peking University
2023 Peking University Teaching Excellence Award
2023 Peking University 'Model Class Collective' Class Teacher
2022 Ministry of Education Top Student Training Program 2.0 Outstanding Teacher Award
2022 Peking University Outstanding Undergraduate Research Training Advisor Award
2021 Invited Speaker Award at the 3rd Young Frontiers Forum in Neurocell Biology
2019 Elected to the Early Career Advisory Board of the Journal of Cell Biology
2016 Most Popular Teacher Award, School of Life Sciences, Peking University
2015 Second Prize in Peking University Young Teacher Teaching Skills Competition
2015 Peking University Teaching Excellence Award
2006 Stanford University Medical School Dean's Postdoctoral Fellowship, USA
2005 Keystone Symposium Abstract Award, USA
2002-2006 Howard Hughes Medical Institute (HHMI) PhD Scholarship, USA

Areas of Focus	Neural stem cell fate determination Molecular mechanisms of neurodevelopment Gene expression programs in brain development
Publications	It takes two to tango: The dance of cell fate specification, Song Y., 2022 Mitotic implantation of a transcription factor via phase separation drives terminal neuronal differentiation, Liu X., Shen J., Xie L., Wei Z., Wong C., Li Y., Zheng X., Li P., Song Y., 2020 The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking, Li B., Wong C., Gao S.M., Zhang R., Sun R., Li Y., Song Y., 2018 Temporospatial induction of homeodomain gene cut dictates natural lineage reprogramming, Xu K., Liu X., Wang Y., Wong C., Song Y., 2018 A genetically-encoded fluorescent acetylcholine indicator for in vitro and in vivo studies, Jing M., Zhang P., Wang G., Jiang H., Mesik L., Feng J., Wang S., Looby J., Guagliardo N.A., Langma L.W., Lu J., Zuo Y., Talmage D.A., Role L.W., Barrett P.Q., Zhang L.I., Luo M., Song Y., Zhu J., Li Y., 2018 The super elongation complex drives neural stem cell fate commitment, Liu K., Shen D., Shen J., Gao S.M., Li B., Wong C., Feng W., Song Y., 2017 Faster, Higher, Stronger: Timely and robust cell fate/identity commitment in stem cell lineages, Liu K., Xu K., Song Y., 2019 The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain, Wu Y.C., Lee K.S., Song Y., Gehrke S., Lu B., 2017 Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway, Lee K.S., Wu Z., Song Y., Mitra S.S., Feroze A.H., Cheshier S.H., Lu B., 2013 Interaction of Notch signaling modulator Numb with α-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells, Song Y., Lu B., 2012 dp53 restrains ectopic neural stem cell formation in the Drosophila brain in a non-apoptotic mechanism involving Archipelago and Cyclin E, Ouyang Y., Song Y., Lu B., 2011 Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila, Song Y., Lu B., 2011 E(nos)/CG4699 required for nanos function in the female germ line of Drosophila, Yu L., Song Y., Wharton R.P., 2010 The molecular chaperone Hsp90 is required for mRNA localization in Drosophila melanogaster embryos, Song Y., Fee L., Lee T., Wharton R.P., 2007

Areas of Focus

Neural stem cell fate determination
Molecular mechanisms of neurodevelopment
Gene expression programs in brain development

Publications

It takes two to tango: The dance of cell fate specification, Song Y., 2022
Mitotic implantation of a transcription factor via phase separation drives terminal neuronal differentiation, Liu X., Shen J., Xie L., Wei Z., Wong C., Li Y., Zheng X., Li P., Song Y., 2020
The retromer complex safeguards against neural progenitor-derived tumorigenesis by regulating Notch receptor trafficking, Li B., Wong C., Gao S.M., Zhang R., Sun R., Li Y., Song Y., 2018
Temporospatial induction of homeodomain gene cut dictates natural lineage reprogramming, Xu K., Liu X., Wang Y., Wong C., Song Y., 2018
A genetically-encoded fluorescent acetylcholine indicator for in vitro and in vivo studies, Jing M., Zhang P., Wang G., Jiang H., Mesik L., Feng J., Wang S., Looby J., Guagliardo N.A., Langma L.W., Lu J., Zuo Y., Talmage D.A., Role L.W., Barrett P.Q., Zhang L.I., Luo M., Song Y., Zhu J., Li Y., 2018
The super elongation complex drives neural stem cell fate commitment, Liu K., Shen D., Shen J., Gao S.M., Li B., Wong C., Feng W., Song Y., 2017
Faster, Higher, Stronger: Timely and robust cell fate/identity commitment in stem cell lineages, Liu K., Xu K., Song Y., 2019
The bantam microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the Drosophila brain, Wu Y.C., Lee K.S., Song Y., Gehrke S., Lu B., 2017
Roles of PINK1, mTORC2, and mitochondria in preserving brain tumor-forming stem cells in a noncanonical Notch signaling pathway, Lee K.S., Wu Z., Song Y., Mitra S.S., Feroze A.H., Cheshier S.H., Lu B., 2013
Interaction of Notch signaling modulator Numb with α-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells, Song Y., Lu B., 2012
dp53 restrains ectopic neural stem cell formation in the Drosophila brain in a non-apoptotic mechanism involving Archipelago and Cyclin E, Ouyang Y., Song Y., Lu B., 2011
Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila, Song Y., Lu B., 2011
E(nos)/CG4699 required for nanos function in the female germ line of Drosophila, Yu L., Song Y., Wharton R.P., 2010
The molecular chaperone Hsp90 is required for mRNA localization in Drosophila melanogaster embryos, Song Y., Fee L., Lee T., Wharton R.P., 2007

Neural Stem Cells Fate Determination Molecular Mechanisms Neurodevelopment Gene Expression Brain Development Cell Differentiation Transcription Factors Chromatin Remodeling Signal Transduction

Chao Chen - Central South University

Wang Wei - University of Chinese Academy of Sciences

Yuewen Chen - University of Chinese Academy of Sciences

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