Professor | Xianchong Chen | Asia Growth Partners

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Name	Xianchong Chen
Contact Information	xc.chen@siat.ac.cn
Language ability	English, Chinese
Province	Guangdong

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Name

Xianchong Chen

Contact Information

xc.chen@siat.ac.cn

Language ability

English, Chinese

Province

Guangdong

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	2009-04--2012-07 PhD: University of Bradford 2009-04--2012-07 MSc: University of Bradford 2005 BSc: The Chinese University of Hong Kong Achievement: Focused on screening co-crystal forms of herbal active molecules to improve solubility
Work Experience	2019-09~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher 2016-10~2019-08 - Actmol Limited - CEO 2012-10~2016-09 - Novartis Pharma Ltd - Postdoctoral Researcher

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

2009-04--2012-07 PhD: University of Bradford
2009-04--2012-07 MSc: University of Bradford
2005 BSc: The Chinese University of Hong Kong
Achievement: Focused on screening co-crystal forms of herbal active molecules to improve solubility

Work Experience

2019-09~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
2016-10~2019-08 - Actmol Limited - CEO
2012-10~2016-09 - Novartis Pharma Ltd - Postdoctoral Researcher

Areas of Focus	Drug crystal form prediction Molecular dynamics calculations GPCR allosteric molecule design
Publications	Translocation Mechanism of Allosteric Sodium Ions in β2-Adrenoceptor, Xueying Wang, Shuguang Yuan, Hin Chung Stephen Chan, 2022 Phase solubility investigation and theoretical calculations on drug-drug cocrystals of carbamazepine with Emodin, Paeonol, Huang, Dandan, Chan, H C Stephen, Wu, Yunshan, Li, Liang, Zhang, Li, Lv, Yang, Yang, Xuemei, Zhou, Zhengzheng, 2021 Enhancing the Signaling of GPCRs via Orthosteric Ions, H C Stephen Chan, Yueming Xu, Liang Tan, Horst Vogel, Jianjun Cheng, Dong Wu, Shuguang Yuan, 2020 Clinical HDAC Inhibitors Are Effective Drugs to Prevent the Entry of SARS-CoV2, Liu, Ke, Zou, Rongfeng, Cui, Wenqiang, Li, Meiqing, Wang, Xueying, Dong, Junlin, Li, Hongchun, Li, Hongpei, Wang, Peihui, Shao, Ximing, Su, Wu, Chan, H C Stephen, Li, Hongchang, Yuan, Shuguang, 2020 New Binding Sites, New Opportunities for GPCR Drug Discovery, Chan, H C Stephen, Li, Yi, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang, 2019 Advancing Drug Discovery via Artificial Intelligence, Chan, H C Stephen, Shan, Hanbin, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang, 2019 Exploring a new ligand binding site of G protein-coupled receptors, Chan, H C Stephen, Wang, Jingjing, Palczewski, Krzysztof, Filipek, Slawomir, Vogel, Horst, Liu, ZhiJie, Yuan, Shuguang, 2018 Rationalization of stereoselectivity in enzyme reactions, Chen Xianchong, 2018 Designing Safer Analgesics via mu-Opioid Receptor Pathways, Chan, H C Stephen, McCarthy, Dillon, Li, Jianing, Palczewski, Krzysztof, Yuan, Shuguang, 2017 The Principles of Ligand Specificity on beta-2-adrenergic receptor, Chan, H C Stephen, Filipek, Slawomir, Yuan, Shuguang, 2016

Areas of Focus

Drug crystal form prediction
Molecular dynamics calculations
GPCR allosteric molecule design

Publications

Translocation Mechanism of Allosteric Sodium Ions in β2-Adrenoceptor, Xueying Wang, Shuguang Yuan, Hin Chung Stephen Chan, 2022
Phase solubility investigation and theoretical calculations on drug-drug cocrystals of carbamazepine with Emodin, Paeonol, Huang, Dandan, Chan, H C Stephen, Wu, Yunshan, Li, Liang, Zhang, Li, Lv, Yang, Yang, Xuemei, Zhou, Zhengzheng, 2021
Enhancing the Signaling of GPCRs via Orthosteric Ions, H C Stephen Chan, Yueming Xu, Liang Tan, Horst Vogel, Jianjun Cheng, Dong Wu, Shuguang Yuan, 2020
Clinical HDAC Inhibitors Are Effective Drugs to Prevent the Entry of SARS-CoV2, Liu, Ke, Zou, Rongfeng, Cui, Wenqiang, Li, Meiqing, Wang, Xueying, Dong, Junlin, Li, Hongchun, Li, Hongpei, Wang, Peihui, Shao, Ximing, Su, Wu, Chan, H C Stephen, Li, Hongchang, Yuan, Shuguang, 2020
New Binding Sites, New Opportunities for GPCR Drug Discovery, Chan, H C Stephen, Li, Yi, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang, 2019
Advancing Drug Discovery via Artificial Intelligence, Chan, H C Stephen, Shan, Hanbin, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang, 2019
Exploring a new ligand binding site of G protein-coupled receptors, Chan, H C Stephen, Wang, Jingjing, Palczewski, Krzysztof, Filipek, Slawomir, Vogel, Horst, Liu, ZhiJie, Yuan, Shuguang, 2018
Rationalization of stereoselectivity in enzyme reactions, Chen Xianchong, 2018
Designing Safer Analgesics via mu-Opioid Receptor Pathways, Chan, H C Stephen, McCarthy, Dillon, Li, Jianing, Palczewski, Krzysztof, Yuan, Shuguang, 2017
The Principles of Ligand Specificity on beta-2-adrenergic receptor, Chan, H C Stephen, Filipek, Slawomir, Yuan, Shuguang, 2016

Crystal Form Prediction Molecular Dynamics Gpcr Allosteric Drug Design Ai Screening Co-Crystal Salt Base

Qi Liu - Tongji University

Dong-Qing Wei - Shanghai Jiao Tong University

Zhi John Lu - Tsinghua University

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