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Xianchong Chen
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: English, Chinese
Crystal Form
Prediction
Molecular Dynamics
Gpcr
Allosteric
Drug Design
Ai
Screening
Co-Crystal
Salt Base
Areas of Focus
- Drug crystal form prediction
- Molecular dynamics calculations
- GPCR allosteric molecule design
Work Experience
- 2019-09~Present - Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences - Associate Researcher
- 2016-10~2019-08 - Actmol Limited - CEO
- 2012-10~2016-09 - Novartis Pharma Ltd - Postdoctoral Researcher
Academic Background & Achievements
- 2009-04--2012-07 PhD: University of Bradford
- 2009-04--2012-07 MSc: University of Bradford
- 2005 BSc: The Chinese University of Hong Kong
- Achievement: Focused on screening co-crystal forms of herbal active molecules to improve solubility
Publications
- Translocation Mechanism of Allosteric Sodium Ions in β2-Adrenoceptor, Xueying Wang, Shuguang Yuan, Hin Chung Stephen Chan, 2022
- Phase solubility investigation and theoretical calculations on drug-drug cocrystals of carbamazepine with Emodin, Paeonol, Huang, Dandan, Chan, H C Stephen, Wu, Yunshan, Li, Liang, Zhang, Li, Lv, Yang, Yang, Xuemei, Zhou, Zhengzheng, 2021
- Enhancing the Signaling of GPCRs via Orthosteric Ions, H C Stephen Chan, Yueming Xu, Liang Tan, Horst Vogel, Jianjun Cheng, Dong Wu, Shuguang Yuan, 2020
- Clinical HDAC Inhibitors Are Effective Drugs to Prevent the Entry of SARS-CoV2, Liu, Ke, Zou, Rongfeng, Cui, Wenqiang, Li, Meiqing, Wang, Xueying, Dong, Junlin, Li, Hongchun, Li, Hongpei, Wang, Peihui, Shao, Ximing, Su, Wu, Chan, H C Stephen, Li, Hongchang, Yuan, Shuguang, 2020
- New Binding Sites, New Opportunities for GPCR Drug Discovery, Chan, H C Stephen, Li, Yi, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang, 2019
- Advancing Drug Discovery via Artificial Intelligence, Chan, H C Stephen, Shan, Hanbin, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang, 2019
- Exploring a new ligand binding site of G protein-coupled receptors, Chan, H C Stephen, Wang, Jingjing, Palczewski, Krzysztof, Filipek, Slawomir, Vogel, Horst, Liu, ZhiJie, Yuan, Shuguang, 2018
- Rationalization of stereoselectivity in enzyme reactions, Chen Xianchong, 2018
- Designing Safer Analgesics via mu-Opioid Receptor Pathways, Chan, H C Stephen, McCarthy, Dillon, Li, Jianing, Palczewski, Krzysztof, Yuan, Shuguang, 2017
- The Principles of Ligand Specificity on beta-2-adrenergic receptor, Chan, H C Stephen, Filipek, Slawomir, Yuan, Shuguang, 2016
