Professor | 陈显翀 | 数字化转型顾问

	Upload Avatar (500 x 500)
Name	陈显翀
Contact Information	xc.chen@siat.ac.cn
Language ability	英语, 中文
Province	广东

Upload Avatar (500 x 500)

Name

陈显翀

Contact Information

xc.chen@siat.ac.cn

Language ability

英语, 中文

Province

广东

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2009-04--2012-07 博士学位: 布莱德福德大学 2009-04--2012-07 硕士学位: 布莱德福德大学 2005 学士学位: 香港中文大学成就: 致力于筛选草药活性分子的共晶晶体，以提高分子的水溶性
Work Experience	2019-09~现在 - 中国科学院深圳先进技术研究院 - 副研究员 2016-10~2019-08 - Actmol Limited有限公司 - 首席执行官 2012-10~2016-09 - 诺华制药公司 - 博士后

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2009-04--2012-07 博士学位: 布莱德福德大学
2009-04--2012-07 硕士学位: 布莱德福德大学
2005 学士学位: 香港中文大学
成就: 致力于筛选草药活性分子的共晶晶体，以提高分子的水溶性

Work Experience

2019-09~现在 - 中国科学院深圳先进技术研究院 - 副研究员
2016-10~2019-08 - Actmol Limited有限公司 - 首席执行官
2012-10~2016-09 - 诺华制药公司 - 博士后

Areas of Focus	药物晶型预测分子动力学计算 GPCR别构分子设计
Publications	Translocation Mechanism of Allosteric Sodium Ions in β2-Adrenoceptor, Xueying Wang, Shuguang Yuan, Hin Chung Stephen Chan, 2022 Phase solubility investigation and theoretical calculations on drug-drug cocrystals of carbamazepine with Emodin, Paeonol, Huang, Dandan, Chan, H C Stephen, Wu, Yunshan, Li, Liang, Zhang, Li, Lv, Yang, Yang, Xuemei, Zhou, Zhengzheng, 2021 Enhancing the Signaling of GPCRs via Orthosteric Ions, H C Stephen Chan, Yueming Xu, Liang Tan, Horst Vogel, Jianjun Cheng, Dong Wu, Shuguang Yuan, 2020 Clinical HDAC Inhibitors Are Effective Drugs to Prevent the Entry of SARS-CoV2, Liu, Ke, Zou, Rongfeng, Cui, Wenqiang, Li, Meiqing, Wang, Xueying, Dong, Junlin, Li, Hongchun, Li, Hongpei, Wang, Peihui, Shao, Ximing, Su, Wu, Chan, H C Stephen, Li, Hongchang, Yuan, Shuguang, 2020 New Binding Sites, New Opportunities for GPCR Drug Discovery, Chan, H C Stephen, Li, Yi, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang, 2019 Advancing Drug Discovery via Artificial Intelligence, Chan, H C Stephen, Shan, Hanbin, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang, 2019 Exploring a new ligand binding site of G protein-coupled receptors, Chan, H C Stephen, Wang, Jingjing, Palczewski, Krzysztof, Filipek, Slawomir, Vogel, Horst, Liu, ZhiJie, Yuan, Shuguang, 2018 Rationalization of stereoselectivity in enzyme reactions, Chen Xianchong, 2018 Designing Safer Analgesics via mu-Opioid Receptor Pathways, Chan, H C Stephen, McCarthy, Dillon, Li, Jianing, Palczewski, Krzysztof, Yuan, Shuguang, 2017 The Principles of Ligand Specificity on beta-2-adrenergic receptor, Chan, H C Stephen, Filipek, Slawomir, Yuan, Shuguang, 2016

Areas of Focus

药物晶型预测
分子动力学计算
GPCR别构分子设计

Publications

Translocation Mechanism of Allosteric Sodium Ions in β2-Adrenoceptor, Xueying Wang, Shuguang Yuan, Hin Chung Stephen Chan, 2022
Phase solubility investigation and theoretical calculations on drug-drug cocrystals of carbamazepine with Emodin, Paeonol, Huang, Dandan, Chan, H C Stephen, Wu, Yunshan, Li, Liang, Zhang, Li, Lv, Yang, Yang, Xuemei, Zhou, Zhengzheng, 2021
Enhancing the Signaling of GPCRs via Orthosteric Ions, H C Stephen Chan, Yueming Xu, Liang Tan, Horst Vogel, Jianjun Cheng, Dong Wu, Shuguang Yuan, 2020
Clinical HDAC Inhibitors Are Effective Drugs to Prevent the Entry of SARS-CoV2, Liu, Ke, Zou, Rongfeng, Cui, Wenqiang, Li, Meiqing, Wang, Xueying, Dong, Junlin, Li, Hongchun, Li, Hongpei, Wang, Peihui, Shao, Ximing, Su, Wu, Chan, H C Stephen, Li, Hongchang, Yuan, Shuguang, 2020
New Binding Sites, New Opportunities for GPCR Drug Discovery, Chan, H C Stephen, Li, Yi, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang, 2019
Advancing Drug Discovery via Artificial Intelligence, Chan, H C Stephen, Shan, Hanbin, Dahoun, Thamani, Vogel, Horst, Yuan, Shuguang, 2019
Exploring a new ligand binding site of G protein-coupled receptors, Chan, H C Stephen, Wang, Jingjing, Palczewski, Krzysztof, Filipek, Slawomir, Vogel, Horst, Liu, ZhiJie, Yuan, Shuguang, 2018
Rationalization of stereoselectivity in enzyme reactions, Chen Xianchong, 2018
Designing Safer Analgesics via mu-Opioid Receptor Pathways, Chan, H C Stephen, McCarthy, Dillon, Li, Jianing, Palczewski, Krzysztof, Yuan, Shuguang, 2017
The Principles of Ligand Specificity on beta-2-adrenergic receptor, Chan, H C Stephen, Filipek, Slawomir, Yuan, Shuguang, 2016

晶型预测分子动力学 Gpcr 别构药物设计人工智能筛选共晶盐基

郭占云 - 同济大学

钱旻 - 华东师范大学

郭占云 - 同济大学

View All

Personal Information

Academic Information

Research

联系我们

还未创建账户?

Personal Information

Academic Information

Research

联系我们