Upload Avatar (500 x 500)
Jingjin Ding
jding@ibp.ac.cn
Chinese, English
Beijing
University of Chinese Academy of Sciences
Life Sciences
  • 2003-09--2008-06 Ph.D. in Science: Institute of Biophysics, Chinese Academy of Sciences
  • 1999-09--2003-06 Bachelor's in Science: College of Life Sciences, Wuhan University
  • 2018-01~Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
  • 2017-01~2017-12 - Institute of Biophysics, Chinese Academy of Sciences - Project Researcher
  • 2012-01~2016-12 - Institute of Biophysics, Chinese Academy of Sciences - Associate Researcher
  • 2010-11~2011-12 - Institute of Biophysics, Chinese Academy of Sciences - Assistant Researcher
  • 2008-10~2010-10 - Institute of Biophysics, Chinese Academy of Sciences - Postdoctoral Researcher
Structural molecular mechanisms of pathogenic bacterial infection and innate immune defense
  • Structural mechanisms of calmodulin activation of Shigella effector OspC3 to ADP-riboxanate caspase-4/11 and block pyroptosis, 11th author, 2023
  • An anti-CD98 antibody displaying pH-dependent Fc-mediated tumour-specific activity against multiple cancers in CD98-humanized mice, 3rd author, 2023
  • ARF GTPases activate Salmonella effector SopF to ADP-ribosylate host V-ATPase and inhibit endomembrane damage-induced autophagy, 11th author, 2022
  • Endomembrane damage sensing by V-ATPase recruits ATG16L1 for LC3 lipidation in situ, 11th author, 2022
  • Calmodulin Binding Activates Chromobacterium CopC Effector to ADP-Riboxanate Host Apoptotic Caspases, 7th author, 2022
  • Structures of heat shock factor trimers bound to DNA, 11th author, 2021
  • Shigella evades pyroptosis by arginine ADP-riboxanation of caspase-11, 12th author, 2021
  • Granzyme A from cytotoxic lymphocytes cleaves GSDMB to trigger pyroptosis in target cells, 14th author, 2020
  • Structural Mechanism for GSDMD Targeting by Autoprocessed Caspases in Pyroptosis, 11th author, 2020
  • A bioorthogonal system reveals antitumour immune function of pyroptosis, 3rd author, 2020
  • Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector, 11th author, 2019
  • A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy, 14th author, 2019
  • Alpha-kinase 1 is a cytosolic innate immune receptor for bacterial ADP-heptose, 14th author, 2018
  • Growing a gasdermin pore in membranes of pyroptotic cells, 11th author, 2018
  • Growing a gasdermin pore in membranes of pyroptotic cells, 11th author, 2018
  • Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin, 4th author, 2017
  • SnapShot: The Noncanonical Inflammasome, 11th author, 2017
  • Biochemical and structural characterization of a DNA N 6 -adenine methyltransferase from Helicobacter pylori, 6th author, 2016
  • Pore-forming activity and structural autoinhibition of the gasdermin family, 1st author, 2016
  • The molecular recognition between cerebral cavernous malformation 2 and mitogen-activated protein kinase kinase kinase 3, 6th author, 2015
  • Structural Insights into the Molecular Recognition between Cerebral Cavernous Malformation 2 and Mitogen-Activated Protein Kinase Kinase Kinase 3, 11th author, 2015
  • Biochemical and Structural Insights into RNA Binding by Ssh10b, a Member of the Highly Conserved Sac10b Protein Family in Archaea, Not mentioned, 2014
  • Structural and Mechanistic Insights into NDM-1 Catalyzed Hydrolysis of Cephalosporins, 2nd author, 2014
  • Structural basis of the ultrasensitive calcium indicator GCaMP6, 1st author, 2014
  • Structural insights into the unique single-stranded DNA-binding mode of Helicobacter pylori DprA, 2nd author, 2014
  • Inflammatory caspases are innate immune receptors for intracellular LPS, Not mentioned, 2014
  • Structural Basis for the Unique Heterodimeric Assembly between Cerebral Cavernous Malformation 3 and Germinal Center Kinase III, Not mentioned, 2013
  • Structural Basis of the Novel S. pneumoniae Virulence Factor, GHIP, a Glycosyl Hydrolase 25 Participating in Host-Cell Invasion, 0th author, 2013
  • Structural Insights into the Pseudomonas aeruginosa Type VI Virulence Effector Tse1 Bacteriolysis and Self-protection Mechanisms, Not mentioned, 2012
  • Crystallization and preliminary X-ray analysis of the C-terminal domain of CCM2, part of a novel adaptor protein involved in cerebral cavernous malformations, 11th author, 2012
  • Three Dimensional Structure of Pseudomonas aeruginosa Tsi2: a Novel Species-specific Antitoxin-like Protein With Coiled Coil Conformation, 2nd author, 2012
  • Three Dimensional Structure of Pseudomonas aeruginosa Tsi2: a Novel Species-specific Antitoxin-like Protein With Coiled Coil Conformation, Not mentioned, 2012
  • Crystallization and preliminary crystallographic studies of CCM3 in complex with the C-terminal domain of MST4, 11th author, 2012
  • Crystal structures of aprataxin ortholog Hnt3 reveal the mechanism for reversal of 5'-adenylated DNA, Not mentioned, 2011
  • Crystal structure of human programmed cell death 10 complexed with inositol-(1,3,4,5)-tetrakisphosphate: A novel adaptor protein involved in human cerebral cavernous malformation, Not mentioned, 2010
  • Crystal structures of a novel anti-HIV mannose-binding lectin from Polygonatum cyrtonema Hua with unique ligand-binding property and super-structure, Not mentioned, 2010
  • Crystallization and Preliminary X-Ray Diffraction Analysis of a Novel Mannose-Binding Lectin with Antiretroviral Properties from Polygonatum cyrtonema Hua, 1st author, 2008
Pathogenic Bacteria Infection Innate Immunity Structural Biology Molecular Mechanisms Immune Defense Pathogen-Host Interaction Biophysics Cell Biology Microbiology

Contact us

Let's talk!
* Required
* Required
* Required
* Invalid email address
By submitting this form, you agree that IoT ONE may contact you with insights and marketing messaging.
No thanks, I don't want to receive any marketing emails from IoT ONE.
Submit

Thank you for your message!
We will contact you soon.