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Huan Fang
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: Chinese, English
Synthetic Biology
Metabolic Engineering
Crispr-Cas9
Escherichia Coli
Vitamin B12
Biotechnology
Genetic Manipulation
Fermentation
Biosynthesis
Microbial Engineering
Areas of Focus
- Synthetic Biology
- Metabolic Engineering
Work Experience
- 2020-07 to Present - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Associate Researcher
- 2018-03 to 2020-07 - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Assistant Researcher
Academic Background & Achievements
- 2013-09 to 2018-01: PhD, Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences
Publications
- Standardized Iterative Genome Editing Method for Escherichia coli Based on CRISPR-Cas9, Huan Fang, 2024
- Multivariate modular metabolic engineering and medium optimization for vitamin B12 production by Escherichia coli, Huan Fang, 2024
- Metabolic engineering of Escherichia coli for production of chemicals derived from the shikimate pathway, Huan Fang, 2020
- Metabolic engineering and optimization of the fermentation medium for vitamin B-12 production in Escherichia coli, Huan Fang, 2020
- Engineering Escherichia coli to improve tryptophan production via genetic manipulation of precursor and cofactor pathways, Huan Fang, 2020
- Bacillus subtilis: a universal cell factory for industry, agriculture, biomaterials and medicine, Huan Fang, 2020
- Biosensor-based monitoring of the central metabolic pathway metabolites, Huan Fang, 2020
- Optimization of hydrogenobyrinic acid biosynthesis in Escherichia coli using multi-level metabolic engineering strategies, Huan Fang, 2020
- Expanding application of CRISPR-Cas9 system in microorganisms, Huan Fang, 2020
- Identification of a xylose-inducible promoter and its application for improving vitamin B12 production in Sinorhizobium meliloti, Huan Fang, 2020
- A multistrategy approach for improving the expression ofE. coliphytase inPichia pastoris, Huan Fang, 2020
- High-Efficiency Secretion and Directed Evolution of Chitinase BcChiA1 in Bacillus subtilis for the Conversion of Chitinaceous Wastes Into Chitooligosaccharides, Huan Fang, 2020
- Metabolic engineering of Escherichia coli for de novo biosynthesis of vitamin B-12, Huan Fang, 2018
Awards
- Tianjin Science and Technology Progress First Prize (2020): Provincial Level
- China National Light Industry Council Science and Technology Progress Award Second Prize (2020): Ministerial Level
