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Shushan Gao
gaoss@tib.cas.cn
Chinese, English
Tianjin
University of Chinese Academy of Sciences
Life Sciences
  • 2006-09--2011-07 PhD: Institute of Oceanology, Chinese Academy of Sciences
  • 2002-09--2006-07 Bachelor's: Soochow University
  • 2022-03~Present - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Researcher
  • 2018-02~2022-03 - Institute of Microbiology, Chinese Academy of Sciences - Researcher
  • 2014-11~2017-06 - University of California, Los Angeles - Postdoctoral Researcher
  • 2011-09~2014-09 - University of Bristol - Postdoctoral Researcher
  • Chinese Academy of Sciences Youth Innovation Promotion Association Outstanding Member (2023): Institute Level
  • Chinese Academy of Sciences Youth Promotion Association (2019): Institute Level
  • Chinese Academy of Sciences Cross-Innovation Cooperation Platform (2019): Other
  • Chinese Academy of Sciences President's Award for Excellence (2011): Institute Level
Microbial Natural Product Biosynthesis and Enzymatic Mechanisms
Protein Engineering and Catalytic Mechanisms in Drug Biosynthesis
Biocatalysis and Synthesis of Medicinal Intermediates
  • Structure-guided semi-rational design of an imine reductase for enantio-complementary synthesis of pyrrolidinamine, Not mentioned, 2023
  • Tuning an Imine Reductase for the Asymmetric Synthesis of Azacycloalkylamines by Concise Structure-Guided Engineering, Not mentioned, 2022
  • Beyond the cyclopropyl ring formation: fungal Aj_EasH catalyzes asymmetric hydroxylation of ergot alkaloids, Not mentioned, 2022
  • Overproduction of medicinal ergot alkaloids based on a fungal platform, Not mentioned, 2022
  • CRISPR-Cas system and anti-CRISPR protein research progress in microorganisms, Not mentioned, 2021
  • Heterologous Production of Unnatural Flavipucine Family Products Provides Insights into Flavipucines Biosynthesis, Not mentioned, 2021
  • TerC Is a Multifunctional and Promiscuous Flavoprotein Monooxygenase That Catalyzes Bimodal Oxidative Transformations, Not mentioned, 2021
  • De novo biosynthesis and gram-level production of m-cresol in Aspergillus nidulans, Not mentioned, 2021
  • A Dual-Plasmid CRISPR/Cas System for Mycotoxin Elimination in Polykaryotic Industrial Fungi, Not mentioned, 2020
  • An anaerobic bacterium host system for heterologous expression of natural product biosynthetic gene clusters, Not mentioned, 2019
  • Catalase Involved in Oxidative Cyclization of the Tetracyclic Ergoline of Fungal Ergot Alkaloids, Not mentioned, 2019
  • Natural medicinal products of fungal origin, Not mentioned, 2019
  • Biosynthesis of Heptacyclic Duclauxins Requires Extensive Redox Modifications of the Phenalenone Aromatic Polyketide, Not mentioned, 2018
  • Recent Examples of β-Ketoglutarate-Dependent Mononuclear Non-Haem Iron Enzymes in Natural Product Biosyntheses, Not mentioned, 2018
  • Genome Mining and Assembly-Line Biosynthesis of the UCS1025A Pyrrolizidinone Family of Fungal Alkaloids, Not mentioned, 2018
  • Selected Mutations Reveal New Intermediates in the Biosynthesis of the Thiomarinols and Mupirocin Antibiotics, Not mentioned, 2017
  • Enzyme-Catalyzed Intramolecular Enantioselective Hydroalkoxylation, Not mentioned, 2017
  • Collaborative Biosynthesis of Maleimide- and Succinimide-Containing Natural Products by Fungal Polyketide Megasynthases, Not mentioned, 2017
  • Identification and Heterologous Production of a Benzoyl-Primed Tricarboxylic Acid Polyketide Intermediate from the Zaragozic Acid A Biosynthetic Pathway, Not mentioned, 2017
  • Elucidation of the relative and absolute stereochemistry of the kalimantacin/batumin antibiotics, Not mentioned, 2017
  • Biochemical Characterization of a Eukaryotic Decalin-Forming Diels-Alderase, Not mentioned, 2016
  • Rhizovarins A-F, Indole-Diterpenes from the Mangrove-Derived Endophytic Fungus Mucor irregularis QEN-189, Not mentioned, 2016
  • Phenalenone Polyketide Cyclization Catalyzed by Fungal Polyketide Synthase and Flavin-Dependent Monooxygenase, Not mentioned, 2016
  • Biosynthesis of Thiomarinol A and Related Metabolites of Pseudoalteromonas SANK73390, Not mentioned, 2014
  • Biosynthesis of Mupirocin by Pseudomonas fluorescens NCIMB 10586 Involves Parallel Pathways, Not mentioned, 2014
  • Chemical constituents of marine mangrove-derived endophytic fungus Alternaria tenuissima EN-192, Not mentioned, 2013
  • Triazoles and Other N-Containing Metabolites from the Marine-Derived Endophytic Fungus Penicillium chrysogenum EN-118, Not mentioned, 2013
  • Two New Secoanthraquinone Derivatives from the Marine-Derived Endophytic Fungus Aspergillus wentii EN-48, Not mentioned, 2013
  • Cytotoxic Anthranilic Acid Derivatives from Deep Sea Sediment-Derived Fungus Penicillium paneum SD-44, Not mentioned, 2013
  • Asperolides A-C, Tetranorlabdane Diterpenoids from the Marine Alga-Derived Endophytic Fungus Aspergillus wentii EN-48, Not mentioned, 2012
  • Secondary Metabolites Produced by Solid Fermentation of the Marine-Derived Fungus Penicillium commune QSD-17, Not mentioned, 2012
  • Chemical profile of the secondary metabolites produced by a deep-sea sediment-derived fungus Penicillium commune SD-118, Not mentioned, 2012
  • Comazaphilones a-f, azaphilone derivatives from the marine sediment-derived fungus penicillium commune qsd-17, Not mentioned, 2011
  • Triazole and Dihydroimidazole Alkaloids from the Marine Sediment-Derived Fungus Penicillium paneum SD-44, Not mentioned, 2011
  • Conidiogenones h and i, two new diterpenes of cyclopiane class from a marine-derived endophytic fungus penicillium chrysogenum qen-24s, Not mentioned, 2011
  • Nigerapyrones a-h, alpha-pyrone derivatives from the marine mangrove-derived endophytic fungus aspergillus niger ma-132, Not mentioned, 2011
  • Penicisteroids A and B, antifungal and cytotoxic polyoxygenated steroids from the marine alga-derived endophytic fungus Penicillium chrysogenum QEN-24S, Not mentioned, 2011
  • Secondary Metabolites from a Marine-Derived Endophytic Fungus Penicillium chrysogenum QEN-24S, Not mentioned, 2010
  • Chemical Constituents of a Marine-Derived Endophytic Fungus Penicillium commune G2M, Not mentioned, 2010
  • Perylene derivatives produced by alternaria alternata, an endophytic fungus isolated from laurencia species, Not mentioned, 2009
Microbial Natural Product Biosynthesis Enzymatic Mechanisms Protein Engineering Catalytic Mechanisms Drug Biosynthesis Biocatalysis Medicinal Intermediates Synthesis

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