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Anwei Hou
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: Chinese, English, German
Natural Products
Biosynthesis
Biocatalysis
Enzymes
Metabolic Engineering
Synthetic Biology
Microbial Biotechnology
Drug Discovery
Biochemical Pathways
Genetic Engineering
Areas of Focus
- Natural Product Discovery and Biosynthesis
- Biocatalysis
Work Experience
- 2024-03~Present - Chinese Academy of Sciences, Tianjin Institute of Industrial Biotechnology - Researcher
- 2022-08~2024-03 - Chinese Academy of Sciences, Tianjin Institute of Industrial Biotechnology - Associate Researcher
- 2018-12~2021-05 - University of Bonn - Postdoctoral Researcher
- 2018-02~2022-06 - Jiangxi Academy of Sciences, Institute of Microbiology - Assistant Researcher
- 2012-08~2014-05 - Zhejiang Yongning Pharmaceutical Co., Ltd. - Experimenter
Academic Background & Achievements
- 2014-09--2017-12 PhD: Wuhan University
- 2009-09--2012-06 Master's: Hubei University of Chinese Medicine
- 2005-09--2009-06 Bachelor's: Hubei University of Chinese Medicine
Publications
- Cladosporin, A Highly Potent Antimalaria Drug?, Corresponding Author, 2023
- Labelling studies in the biosynthesis of polyketides and non-ribosomal peptides, First Author, 2023
- Mechanism of the Bifunctional Multiple Product Sesterterpene Synthase AcAS from Aspergillus calidoustus, Second Author, 2022
- Discovery of non-squalene triterpenes, Fifth Author, 2022
- Deceptive Complexity in Formation of Cleistantha-8,12-diene, Fourth Author, 2022
- The stereochemical course of 2-methylisoborneol biosynthesis, Second Author, 2022
- Using Terpene Synthase Plasticity in Catalysis: On the Enzymatic Conversion of Synthetic Farnesyl Diphosphate Analogues, First Author, 2021
- Rerouting and Improving Dauc-8-en-11-ol Synthase from Streptomyces venezuelae to a High Yielding Biocatalyst, Second Author, 2021
- A Flavoprotein Dioxygenase Steers Bacterial Tropone Biosynthesis via Coenzyme A-Ester Oxygenolysis and Ring Epoxidation, Third Author, 2021
- Functional Switch and Ethyl Group Formation in the Bacterial Polytrichastrene Synthase from Chryseobacterium polytrichastri, First Author, 2021
- The EI-MS Fragmentation Mechanisms of the Bacterial Diterpenes Polytrichastrene A and Wanju-2,5-diene, First Author, 2021
- Targeting active site residues and structural anchoring positions in terpene synthases, First Author, 2021
- The Biosynthetic Gene Cluster for Sestermobaraenes-Discovery of a Geranylfarnesyl Diphosphate Synthase and a Multiproduct Sesterterpene Synthase fromStreptomyces mobaraensis, First Author, 2020
- Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases, Sixth Author, 2020
- On the mass spectrometric fragmentations of the bacterial sesterterpenes sestermobaraenes A-C, First Author, 2020
- Enzymatic Synthesis of Methylated Terpene Analogues Using the Plasticity of Bacterial Terpene Synthases, First Author, 2020
- Metabolic Engineering-Based Rapid Characterization of a Sesquiterpene Cyclase and the Skeletons of Fusariumdiene and Fusagramineol from Fusarium graminearum, Second Author, 2018
- A Clade II-D Fungal Chimeric Diterpene Synthase from Colletotrichum gloeosporioides Produces Dolasta-1(15),8-diene, Fifth Author, 2018
- Releasing the potential power of terpene synthases by a robust precursor supply platform, Third Author, 2017
- Substrate screening of amino transaminase for the synthesis of a sitagliptin intermediate, First Author, 2016
