Areas of Focus
- 天然产物发现与生物合成
- 生物催化
Work Experience
- 2024-03~现在 - 中国科学院天津工业生物技术研究所 - 研究员
- 2022-08~2024-03 - 中国科学院天津工业生物技术研究所 - 副研究员
- 2018-12~2021-05 - 德国波恩大学 - 博士后
- 2018-02~2022-06 - 江西省科学院微生物研究所 - 助理研究员
- 2012-08~2014-05 - 浙江永宁药业股份有限公司 - 实验员
Academic Background & Achievements
- 2014-09--2017-12 博士研究生: 武汉大学
- 2009-09--2012-06 硕士研究生: 湖北中医药大学
- 2005-09--2009-06 本科学习: 湖北中医药大学
Publications
- Cladosporin, A Highly Potent Antimalaria Drug?, 通讯作者, 2023
- Labelling studies in the biosynthesis of polyketides and non-ribosomal peptides, 第一作者, 2023
- Mechanism of the Bifunctional Multiple Product Sesterterpene Synthase AcAS from Aspergillus calidoustus, 第二作者, 2022
- Discovery of non-squalene triterpenes, 第五作者, 2022
- Deceptive Complexity in Formation of Cleistantha-8,12-diene, 第四作者, 2022
- The stereochemical course of 2-methylisoborneol biosynthesis, 第二作者, 2022
- Using Terpene Synthase Plasticity in Catalysis: On the Enzymatic Conversion of Synthetic Farnesyl Diphosphate Analogues, 第一作者, 2021
- Rerouting and Improving Dauc-8-en-11-ol Synthase from Streptomyces venezuelae to a High Yielding Biocatalyst, 第二作者, 2021
- A Flavoprotein Dioxygenase Steers Bacterial Tropone Biosynthesis via Coenzyme A-Ester Oxygenolysis and Ring Epoxidation, 第三作者, 2021
- Functional Switch and Ethyl Group Formation in the Bacterial Polytrichastrene Synthase from Chryseobacterium polytrichastri, 第一作者, 2021
- The EI-MS Fragmentation Mechanisms of the Bacterial Diterpenes Polytrichastrene A and Wanju-2,5-diene, 第一作者, 2021
- Targeting active site residues and structural anchoring positions in terpene synthases, 第一作者, 2021
- The Biosynthetic Gene Cluster for Sestermobaraenes-Discovery of a Geranylfarnesyl Diphosphate Synthase and a Multiproduct Sesterterpene Synthase fromStreptomyces mobaraensis, 第一作者, 2020
- Discovery of the cryptic function of terpene cyclases as aromatic prenyltransferases, 第六作者, 2020
- On the mass spectrometric fragmentations of the bacterial sesterterpenes sestermobaraenes A-C, 第一作者, 2020
- Enzymatic Synthesis of Methylated Terpene Analogues Using the Plasticity of Bacterial Terpene Synthases, 第一作者, 2020
- Metabolic Engineering-Based Rapid Characterization of a Sesquiterpene Cyclase and the Skeletons of Fusariumdiene and Fusagramineol from Fusarium graminearum, 第二作者, 2018
- A Clade II-D Fungal Chimeric Diterpene Synthase from Colletotrichum gloeosporioides Produces Dolasta-1(15),8-diene, 第五作者, 2018
- Releasing the potential power of terpene synthases by a robust precursor supply platform, 第三作者, 2017
- Substrate screening of amino transaminase for the synthesis of a sitagliptin intermediate, 第一作者, 2016