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Liangyu Huang
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: English, Chinese
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Biomacromolecules Liquid-Liquid Phase Separation Regulation Mechanism Neurodegenerative Diseases Molecular Mechanisms Protein Nmr Biophysics Cell Signaling
Areas of Focus
  • Mechanism and Regulation of Liquid-Liquid Phase Separation of Biomacromolecules
  • Molecular Mechanisms of Neurodegenerative Diseases
Work Experience
  • 2021-11~Present - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Associate Researcher
  • 2020-11~2021-11 - Chinese Academy of Sciences Shenzhen Institute of Advanced Technology - Senior Engineer
  • 2018-11~2020-07 - University of Toronto - Postdoctoral Fellow
  • 2012-09~2018-10 - Max Planck Institute for Biophysical Chemistry - Visiting Student, Postdoctoral Fellow
Academic Background & Achievements
  • 2008-08--2013-10 PhD: Nanyang Technological University
  • 2003-08--2007-07 Bachelor: National University of Singapore
Publications
  • PNAS Nexusnull, Huang Liangyu, 2024
  • Confronting the Invisible: Assignment of Protein 1HN Chemical Shifts in Cases of Extreme Broadening, Huang Liangyu, 2020
  • NMR Experiments for Studies of Dilute and Condensed Protein Phases: Application to the Phase-Separating Protein CAPRIN1, Wong, Leo E, Kim, Tae Hun, Muhandiram, D Ranjith, FormanKay, Julie D, Kay, Lewis E., 2020
  • Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness, Leo E. Wong, Arshiya Bhatt, Philipp S. Erdmann, Zhen Hou, Joachim Maier, Sona Pirkuliyeva, Michael Engelke, Stefan Becker, Jrgen Plitzko, Jrgen Wienands, Christian Griesinger, 2020
  • A methyl-TROSY approach for NMR studies of high-molecular-weight DNA with application to the nucleosome core particle, Abramov, Gili, Velyvis, Algirdas, Rennella, Enrico, Wong, Leo E, Kay, Lewis E., 2020
  • Sensitivity-Enhanced Four-Dimensional Amide-Amide Correlation NMR Experiments for Sequential Assignment of Proline-Rich Disordered Proteins, Wong, Leo E, Maier, Joachim, Wienands, Juergen, Becker, Stefan, Griesinger, Christian, 2018
  • The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation, Kuehn, Julius, Wong, Leo E, Pirkuliyeva, Sona, Schulz, Kathrin, Schwiegk, Claudia, Fuenfgeld, Kevser Gencalp, Keppler, Selina, Batista, Facundo D, Urlaub, Henning, Habeck, Michael, Becker, Stefan, Griesinger, Christian, Wienands, Juergen, 2016
  • Macromolecular assembly of the adaptor SLP-65 at intracellular vesicles in resting B cells, Engelke, Michael, Pirkuliyeva, Sona, Kuehn, Julius, Wong, Leo, Boyken, Janina, Herrmann, Nadine, Becker, Stefan, Griesinger, Christian, Wienands, Juergen, 2014
  • Selectivity of stop codon recognition in translation termination is modulated by multiple conformations of GTS loop in eRF1, Wong, Leo E, Li, Yan, Pillay, Shubhadra, Frolova, Ludmila, Pervushin, Konstantin, 2012
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