Professor | 黄良宇 | 数字化转型顾问

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Name	黄良宇
Contact Information	leo.wong@siat.ac.cn
Language ability	英语, 中文
Province	广东

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Name

黄良宇

Contact Information

leo.wong@siat.ac.cn

Language ability

英语, 中文

Province

广东

University/Lab Affiliation and Title	中国科学院大学
Faculty	Life Sciences
Academic Background & Achievements	2008-08--2013-10 博士: 南洋理工大学 2003-08--2007-07 学士: 新加坡国立大学
Work Experience	2021-11~现在 - 中科院深圳先进技术研究院 - 副研究员 2020-11~2021-11 - 中科院深圳先进技术研究院 - 高级工程师 2018-11~2020-07 - 多伦多大学 - 博士后 2012-09~2018-10 - 马普所生物物理化学所 - 客座学生、博士后

University/Lab Affiliation and Title

中国科学院大学

Faculty

Life Sciences

Academic Background & Achievements

2008-08--2013-10 博士: 南洋理工大学
2003-08--2007-07 学士: 新加坡国立大学

Work Experience

2021-11~现在 - 中科院深圳先进技术研究院 - 副研究员
2020-11~2021-11 - 中科院深圳先进技术研究院 - 高级工程师
2018-11~2020-07 - 多伦多大学 - 博士后
2012-09~2018-10 - 马普所生物物理化学所 - 客座学生、博士后

Areas of Focus	生物大分子液相分离的机制与调控神经退行性疾病的分子机制
Publications	PNAS Nexusnull, 黄良宇, 2024 Confronting the Invisible: Assignment of Protein 1HN Chemical Shifts in Cases of Extreme Broadening, 黄良宇, 2020 NMR Experiments for Studies of Dilute and Condensed Protein Phases: Application to the Phase-Separating Protein CAPRIN1, Wong, Leo E, Kim, Tae Hun, Muhandiram, D Ranjith, FormanKay, Julie D, Kay, Lewis E., 2020 Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness, Leo E. Wong, Arshiya Bhatt, Philipp S. Erdmann, Zhen Hou, Joachim Maier, Sona Pirkuliyeva, Michael Engelke, Stefan Becker, Jrgen Plitzko, Jrgen Wienands, Christian Griesinger, 2020 A methyl-TROSY approach for NMR studies of high-molecular-weight DNA with application to the nucleosome core particle, Abramov, Gili, Velyvis, Algirdas, Rennella, Enrico, Wong, Leo E, Kay, Lewis E., 2020 Sensitivity-Enhanced Four-Dimensional Amide-Amide Correlation NMR Experiments for Sequential Assignment of Proline-Rich Disordered Proteins, Wong, Leo E, Maier, Joachim, Wienands, Juergen, Becker, Stefan, Griesinger, Christian, 2018 The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation, Kuehn, Julius, Wong, Leo E, Pirkuliyeva, Sona, Schulz, Kathrin, Schwiegk, Claudia, Fuenfgeld, Kevser Gencalp, Keppler, Selina, Batista, Facundo D, Urlaub, Henning, Habeck, Michael, Becker, Stefan, Griesinger, Christian, Wienands, Juergen, 2016 Macromolecular assembly of the adaptor SLP-65 at intracellular vesicles in resting B cells, Engelke, Michael, Pirkuliyeva, Sona, Kuehn, Julius, Wong, Leo, Boyken, Janina, Herrmann, Nadine, Becker, Stefan, Griesinger, Christian, Wienands, Juergen, 2014 Selectivity of stop codon recognition in translation termination is modulated by multiple conformations of GTS loop in eRF1, Wong, Leo E, Li, Yan, Pillay, Shubhadra, Frolova, Ludmila, Pervushin, Konstantin, 2012

Areas of Focus

生物大分子液相分离的机制与调控
神经退行性疾病的分子机制

Publications

PNAS Nexusnull, 黄良宇, 2024
Confronting the Invisible: Assignment of Protein 1HN Chemical Shifts in Cases of Extreme Broadening, 黄良宇, 2020
NMR Experiments for Studies of Dilute and Condensed Protein Phases: Application to the Phase-Separating Protein CAPRIN1, Wong, Leo E, Kim, Tae Hun, Muhandiram, D Ranjith, FormanKay, Julie D, Kay, Lewis E., 2020
Tripartite phase separation of two signal effectors with vesicles priming B cell responsiveness, Leo E. Wong, Arshiya Bhatt, Philipp S. Erdmann, Zhen Hou, Joachim Maier, Sona Pirkuliyeva, Michael Engelke, Stefan Becker, Jrgen Plitzko, Jrgen Wienands, Christian Griesinger, 2020
A methyl-TROSY approach for NMR studies of high-molecular-weight DNA with application to the nucleosome core particle, Abramov, Gili, Velyvis, Algirdas, Rennella, Enrico, Wong, Leo E, Kay, Lewis E., 2020
Sensitivity-Enhanced Four-Dimensional Amide-Amide Correlation NMR Experiments for Sequential Assignment of Proline-Rich Disordered Proteins, Wong, Leo E, Maier, Joachim, Wienands, Juergen, Becker, Stefan, Griesinger, Christian, 2018
The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation, Kuehn, Julius, Wong, Leo E, Pirkuliyeva, Sona, Schulz, Kathrin, Schwiegk, Claudia, Fuenfgeld, Kevser Gencalp, Keppler, Selina, Batista, Facundo D, Urlaub, Henning, Habeck, Michael, Becker, Stefan, Griesinger, Christian, Wienands, Juergen, 2016
Macromolecular assembly of the adaptor SLP-65 at intracellular vesicles in resting B cells, Engelke, Michael, Pirkuliyeva, Sona, Kuehn, Julius, Wong, Leo, Boyken, Janina, Herrmann, Nadine, Becker, Stefan, Griesinger, Christian, Wienands, Juergen, 2014
Selectivity of stop codon recognition in translation termination is modulated by multiple conformations of GTS loop in eRF1, Wong, Leo E, Li, Yan, Pillay, Shubhadra, Frolova, Ludmila, Pervushin, Konstantin, 2012

生物大分子液相分离调控机制神经退行性疾病分子机制蛋白质核磁共振生物物理细胞信号

孙方霖 - 同济大学

Area of Focus
表观遗传学 | 分子机制 | 调控 | 异染色质 | 结构 | 功能 | 干细胞 | 衰老 | 网络 | 研究

张梦杰 - 同济大学

Area of Focus
基因表达 | 调控 | 组织 | 干细胞 | 发育 | 分化 | 模式生物 | Survivin | 癌症治疗 | 分子机制

顾华 - 同济大学

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