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Wenshuai Liu
Life Science
University of Chinese Academy of Sciences
Shandong
Language: Chinese, English
Contact
Nanobodies Medical Applications Health Applications Antibodies Diagnostics Targeted Drugs Research Platform Technology Development Full Process Advanced Techniques
Areas of Focus
  • Nanobodies for Medical and Health Applications
Work Experience
  • 2020-01~Present - Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences - Associate Researcher
  • 2018-10~2020-01 - Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences - Assistant Researcher
  • 2016-07~2018-10 - Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences - Postdoctoral Researcher
Academic Background & Achievements
  • 2011-09--2016-06 Ph.D.: China Agricultural University
  • 2007-09--2011-06 Bachelor's: Shandong Agricultural University
Publications
  • Novel Polystyrene-Binding Nanobody for Enhancing Immunoassays: Insights into Affinity, Immobilization, and Application Potential, Wenshuai Liu, 2024
  • Optimized silk fibroin nanoparticle functionalization with anti-CEA nanobody enhancing active targeting of colorectal cancer cells, Wenshuai Liu, 2023
  • Development of a highly sensitive immunoassay based on pentameric nanobodies for carcinoembryonic antigen detection, Wenshuai Liu, 2023
  • Dual CEA/CD44 targeting to colorectal cancer cells using nanobody-conjugated hyaluronic acidmodified mesoporous silica nanoparticles with pH- and redox-sensitivity, Wenshuai Liu, 2022
  • Targeting and neutralizing human epididymis protein 4 by novel nanobodies to suppress ovarian cancer cells and attenuate cisplatin resistance, Wenshuai Liu, 2022
  • A novel silk fibroin protein–based fusion system for enhancing the expression of nanobodies in Escherichia coli, Wenshuai Liu, 2022
  • Integrated purification of a nanobody using ammonium sulfate precipitation and Capto MMC, Wenshuai Liu, 2020
  • Production of functional human nerve growth factor from the submandibular glands of mice using a CRISPR/Cas9 genome editing system, Wenshuai Liu, 2020
  • Improved Cell Viability and Biocompatibility of Bacterial Cellulose through in Situ Carboxymethylation., Wenshuai Liu, 2019
  • An efficient constitutive expression system for Anti-CEACAM5 nanobody production in the yeast Pichia pastoris, Wenshuai Liu, 2019
  • Salt-enhanced permeabilization for monoclonal antibody precipitation and purification in a tubular reactor with a depth filtration membrane with advanced chromatin extraction, Wenshuai Liu, 2019
  • A facile fabrication of stimulus-responsive amorphous photonic crystals in the near-infrared region, Wenshuai Liu, 2019
  • Reduction of chromatin heteroaggregates by acid precipitation of mammalian cell culture and ramification in protein A chromatography for recombinant immunoglobulin G purification, Wenshuai Liu, 2019
  • Advance chromatin extraction improves the performance of electropositive mixed-mode chromatography as a capture step and enables its integration with void-exclusion anion exchange chromatography as a two-column-step purification platform for monoclonal antibody production, Wenshuai Liu, 2019
  • Non-affinity purification of a nanobody by void-exclusion anion exchange chromatography and multimodal weak cation exchange chromatography, Wenshuai Liu, 2019
  • Chromatin-directed clarification in cell culture fluid enables non-protein affinity antibody purification by tangential flow filtration integrated with high-capacity cation exchange chromatography, Wenshuai Liu, 2019
  • A seamless and nonprotein A-based monoclonal antibody purification platform using void-exclusion anion exchange chromatography and electropositive multimodal chromatography enhanced by advance chromatin extraction, Wenshuai Liu, 2019
  • Recent advances in the selection and identification of antigen-specific nanobodies, Wenshuai Liu, 2018
  • Increasing Avermectin Production in Streptomyces avermitilis by Manipulating the Expression of a Novel TetR-Family Regulator and Its Target Gene Product, Wenshuai Liu, 2015
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