Areas of Focus
- 面向医养健康领域的纳米抗体
Work Experience
- 2020-01~现在 - 中国科学院青岛生物能源与过程研究所 - 副研究员
- 2018-10~2020-01 - 中国科学院青岛生物能源与过程研究所 - 助理研究员
- 2016-07~2018-10 - 中国科学院青岛生物能源与过程研究所 - 博士后
Academic Background & Achievements
- 2011-09--2016-06 博士研究生: 中国农业大学
- 2007-09--2011-06 学士: 山东农业大学
Publications
- Novel Polystyrene-Binding Nanobody for Enhancing Immunoassays: Insights into Affinity, Immobilization, and Application Potential, 刘文帅, 2024
- Optimized silk fibroin nanoparticle functionalization with anti-CEA nanobody enhancing active targeting of colorectal cancer cells, 刘文帅, 2023
- Development of a highly sensitive immunoassay based on pentameric nanobodies for carcinoembryonic antigen detection, 刘文帅, 2023
- Dual CEA/CD44 targeting to colorectal cancer cells using nanobody-conjugated hyaluronic acidmodified mesoporous silica nanoparticles with pH- and redox-sensitivity, 刘文帅, 2022
- Targeting and neutralizing human epididymis protein 4 by novel nanobodies to suppress ovarian cancer cells and attenuate cisplatin resistance, 刘文帅, 2022
- A novel silk fibroin protein–based fusion system for enhancing the expression of nanobodies in Escherichia coli, 刘文帅, 2022
- Integrated purification of a nanobody using ammonium sulfate precipitation and Capto MMC, 刘文帅, 2020
- Production of functional human nerve growth factor from the submandibular glands of mice using a CRISPR/Cas9 genome editing system, 刘文帅, 2020
- Improved Cell Viability and Biocompatibility of Bacterial Cellulose through in Situ Carboxymethylation., 刘文帅, 2019
- An efficient constitutive expression system for Anti-CEACAM5 nanobody production in the yeast Pichia pastoris, 刘文帅, 2019
- Salt-enhanced permeabilization for monoclonal antibody precipitation and purification in a tubular reactor with a depth filtration membrane with advanced chromatin extraction, 刘文帅, 2019
- A facile fabrication of stimulus-responsive amorphous photonic crystals in the near-infrared region, 刘文帅, 2019
- Reduction of chromatin heteroaggregates by acid precipitation of mammalian cell culture and ramification in protein A chromatography for recombinant immunoglobulin G purification, 刘文帅, 2019
- Advance chromatin extraction improves the performance of electropositive mixed-mode chromatography as a capture step and enables its integration with void-exclusion anion exchange chromatography as a two-column-step purification platform for monoclonal antibody production, 刘文帅, 2019
- Non-affinity purification of a nanobody by void-exclusion anion exchange chromatography and multimodal weak cation exchange chromatography, 刘文帅, 2019
- Chromatin-directed clarification in cell culture fluid enables non-protein affinity antibody purification by tangential flow filtration integrated with high-capacity cation exchange chromatography, 刘文帅, 2019
- A seamless and nonprotein A-based monoclonal antibody purification platform using void-exclusion anion exchange chromatography and electropositive multimodal chromatography enhanced by advance chromatin extraction, 刘文帅, 2019
- Recent advances in the selection and identification of antigen-specific nanobodies, 刘文帅, 2018
- Increasing Avermectin Production in Streptomyces avermitilis by Manipulating the Expression of a Novel TetR-Family Regulator and Its Target Gene Product, 刘文帅, 2015
