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Tao Liu
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: English, Chinese
Biosynthesis
Natural Products
Microbial
Physiology
Metabolism
Genetic Engineering
Biotechnology
Synthetic Biology
Metabolic Pathways
Enzymes
Areas of Focus
- Natural Product Biosynthesis
- Microbial Physiology and Metabolism
Work Experience
- 2011-05~Present - Tianjin Institute of Industrial Biotechnology - Researcher
- 2009-03~2011-04 - SelectX Pharmaceuticals Inc - Researcher/Department Head
- 2006-09~2009-03 - University of Wisconsin-Madison - Postdoctoral Research Assistant
- 2002-08~2006-08 - University of Kentucky - PhD
Academic Background & Achievements
- 2002-08--2006-08 PhD: University of Kentucky
- Achievement 1: 30th National Medicinal Chemistry Symposium Travel Award, 2006
- Achievement 2: University of Kentucky Graduate School Academic Year Scholarship, 2005
- Achievement 3: University of Kentucky Graduate Scholarship, 2004
Publications
- High-level production of Rhodiola rosea characteristic component rosavin from D-glucose and L-arabinose in engineered Escherichia coli, Tao Liu, 2024
- Complete biosynthesis of the phenylethanoid glycoside verbascoside, Tao Liu, 2023
- Biosynthesis of a rosavin natural product in Escherichia coli by glycosyltransferase rational design and artificial pathway construction, Tao Liu, 2022
- Advances in microbial synthesis of plant natural products, Tao Liu, 2022
- Biosynthesis of cinnamyl acetate by three plant-derived benzyl acyltransferases in engineered Escherichia coli, Tao Liu, 2021
- CYP82AR Subfamily Proteins Catalyze C-1 ' Hydroxylations of Deoxyshikonin in the Biosynthesis of Shikonin and Alkannin, Tao Liu, 2021
- Discovery of Glycosyltransferases Involved in the Biosynthesis of Ligupurpuroside B, Tao Liu, 2021
- Production of caffeyl alcohol glucosides by mixed fermentation with different Escherichia coli recombinants, Tao Liu, 2020
- Potential role of two cytochrome P450s obtained from Lithospermum erythrorhizon in catalyzing the oxidation of geranylhydroquinone during Shikonin biosynthesis, Tao Liu, 2020
- Origin and Evolution of Fusidane-Type Antibiotics Biosynthetic Pathway through Multiple Horizontal Gene Transfers, Tao Liu, 2020
- Metabolic engineering of Saccharomyces cerevisiae for high-level production of gastrodin from glucose, Tao Liu, 2020
- Producing Gram-Scale Unnatural Rosavin Analogues from Glucose by Engineered Escherichia coli, Tao Liu, 2019
- Research progress on the biosynthesis of aromatic compounds by microorganisms, Tao Liu, 2019
- Production of caffeoylmalic acid from glucose in engineered Escherichia coli, Tao Liu, 2018
- Genetic Cloning and Functional Verification of Hydroxycinnamoyltransferase in Ixeris sonchifolia Hance, Tao Liu, 2018
- Metabolic Engineering of Saccharomyces cerevisiae for High-Level Production of Salidroside from Glucose, Tao Liu, 2018
- Production of Cinnamyl Alcohol Glucoside from Glucose in Escherichia coli, Tao Liu, 2017
- Biosynthesis of 3-(4-Hydroxyphenyl)Propionic Acid in Saccharomyces cerevisiae, Tao Liu, 2017
- Balanced activation of IspG and IspH to eliminate MEP intermediate accumulation and improve isoprenoids production in Escherichia coli, Tao Liu, 2017
- Biocatalysis of Phenolic Glycosides Natural Products in Escherichia coli Strain Using UGT73B6, Tao Liu, 2017
- Biosynthesis of Valerena-4,7(11)-diene in an Engineered Escherichia coli Strain, Tao Liu, 2017
- Fermentative Production of Phenolic Glucosides by Escherichia coli with an Engineered Glucosyltransferase from Rhodiola sachalinensis, Tao Liu, 2017
- De novo biosynthesis of Gastrodin in Escherichia coli, Tao Liu, 2016
- Synthesis of rosmarinic acid analogues in Escherichia coli, Tao Liu, 2016
- Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose, Tao Liu, 2016
- Engineered synthesis of rosmarinic acid in Escherichia coli resulting production of a new intermediate, caffeoyl-phenyllactate, Tao Liu, 2016
- Heterologous expression of bottromycin biosynthetic gene cluster and increase of yield, Tao Liu, 2015
- Heterologous biosynthesis of costunolide in Escherichia coli and yield improvement, Tao Liu, 2015
- Three New Xanthones from the Fungus Penicillium sp NH-7-1, Tao Liu, 2015
- Producing aglycons of ginsenosides in bakers’ yeast, Tao Liu, 2014
- The preliminary identification of piloquinone biosynthetic gene cluster, Tao Liu, 2014
- Production of lycopene by metabolically-engineered Escherichia coli, Tao Liu, 2014
- Production of salidroside in metabolically engineered Escherichia coli, Tao Liu, 2014
- Draft Genome Sequence of Streptomyces bottropensis ATCC 25435, a Bottromycin-Producing Actinomycete, Tao Liu, 2013
- Engineered short branched-chain acyl-CoA synthesis in E. coli and acylation of chloramphenicol to branched-chain derivatives, Tao Liu, 2013
- Engineered Biosynthesis of Gilvocarcin Analogues with Altered Deoxyhexopyranose Moieties, Tao Liu, 2011
- Characterization of the lnmKLM Genes Unveiling Key Intermediates for β-Alkylation in Leinamycin Biosynthesis, Tao Liu, 2010
- Inactivation of the Ketoreductase gilU Gene of the Gilvocarcin Biosynthetic Gene Cluster Yields New Analogues with Partly Improved Biological Activity, Tao Liu, 2009
- Bifunctional acyltransferase/decarboxylase LnmK as the missing link for β-alkylation in polyketide biosynthesis, Tao Liu, 2009
- Multi-Oxygenase Complexes of the Gilvocarcin and Jadomycin Biosyntheses, Tao Liu, 2007
- Inactivation of gilGT encoding a C-Glycosyltransferse and gilOIII encoding a P450-enzyme, allows to delineate details of the biosynthetic pathway of gilvocarcin V, Tao Liu, 2006
- Generation of New Landomycins by Combinatorial Biosynthetic Manipulation of the LndGT4 Gene of the Landomycin E Cluster in S. globisporus, Tao Liu, 2004
- Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis, Tao Liu, 2004
- Oxidative rearrangement processes in the biosynthesis of gilvocarcin V, Tao Liu, 2004
- Biosynthesis of phlorisovalerophenone and 4-hydroxy-6-isobutyl-2-pyrone in Escherichia coli from glucose, Tao Liu
Awards
- 30th National Medicinal Chemistry Symposium Travel Award (2006): Other
- University of Kentucky Graduate School Academic Year Scholarship (2005): Institution
- University of Kentucky Graduate Scholarship (2004): Institution
