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Ke Liu
Life Science
University of Chinese Academy of Sciences
Guangdong
Language: Chinese, English
Natural Peptides
Anti-Tumor
High-Throughput Screening
Bioactivity
Molecular Targets
Biomimetic
Artificial Peptides
Cancer Therapy
Peptide Synthesis
Tumor Targeting
Areas of Focus
- High-throughput screening of natural peptides with anti-tumor bioactivity
- Identification of new anti-tumor natural peptide molecular targets
- Design and synthesis of biomimetic artificial peptide molecules for anti-tumor therapy
Academic Background & Achievements
- 2009-09 to 2014-06 Ph.D. in Science: Sichuan University, State Key Laboratory of Biotherapy
- 2005-09 to 2009-07 Bachelor's in Science: Sichuan University, College of Life Sciences/Wu Yuzhang Honors College
Publications
- Coibamide A kills cancer cells through inhibiting autophagy, Shi, Wenli, Lu, Danyi, Wu, Chunlei, Li, Meiqing, Ding, Zhihao, Li, Yanyan, Chen, Binghua, Lin, Xian, Su, Wu, Shao, Ximing, Xia, Zhihui, Fang, Lijing, Liu, Ke, Li, Hongchang, 2021
- Novel N-Methylated Cyclodepsipeptide Prodrugs for Targeted Cancer Therapy, Wu, Chunlei, Cheng, Zhehong, Lu, Danyi, Liu, Ke, Cheng, Yulian, Wang, Pengxin, Zhou, Yimin, Li, Meiqing, Shao, Ximing, Li, Hongchang, Su, Wu, Fang, Lijing, 2021
- Aligned Biofunctional Electrospun PLGA-LysoGM1 Scaffold for Traumatic Brain Injury Repair, Tang, Wei, Fang, Fei, Ke, Liu, Huang, Zhi, Li, Hui, Yin, Ying, Wang, Jun, Wang, Guocheng, Wei, Liyu, Ou, Yun, Wang, Yazhou, 2020
- Clinical HDAC Inhibitors Are Effective Drugs to Prevent the Entry of SARS-CoV2, Liu, Ke, Zou, Rongfeng, Cui, Wenqiang, Li, Meiqing, Wang, Xueying, Dong, Junlin, Li, Hongchun, Li, Hongpei, Wang, Peihui, Shao, Ximing, Su, Wu, Chan, H C Stephen, Li, Hongchang, Yuan, Shuguang, 2020
- Chlorotoxin-derived bicyclic peptides for targeted imaging of glioblastomas, Li, Meiqing, Shao, Ximing, Wu, Chunlei, Lu, Danyi, Liu, Ke, Wang, Wei, Liu, Jiakai, Li, Hongchang, Su, Wu, Fang, Lijing, 2020
- Improved Total Synthesis and Biological Evaluation of Coibamide A Analogues, Yao, Guiyang, Wang, Wei, Ao, Lijiao, Cheng, Zhehong, Wu, Chunlei, Pang, Zhengyin, Liu, Ke, Li, Hongchang, Su, Wu, Fang, Lijing, 2018
- Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo, Liu, Ke, Fang, Lijing, Sun, Haiyan, Pan, Zhengyin, Zhang, Jianchao, Chen, Juntao, Shao, Ximing, Wang, Wei, Tan, Yuanyan, Ding, Zhihao, Ao, Lijiao, Wu, Chunlei, Liu, Xiaoqi, Li, Huashun, Wang, Rui, Su, Wu, Li, Hongchang, 2018
- Polydopamine-Derivated Hierarchical Nanoplatforms for Efficient Dual-Modal Imaging-Guided Combination in Vivo Cancer Therapy, Ao, Lijiao, Wu, Chunlei, Liu, Ke, Wang, Wei, Fang, Lijing, Huang, Liang, Su, Wu, 2018
- Improved Total Synthesis and Biological Evaluation of Coibamide A Analogues, Yao, Guiyang, Wang, Wei, Ao, Lijiao, Cheng, Zhehong, Wu, Chunlei, Pang, Zhengyin, Liu, Ke, Li, Hongchang, Su, Wu, Fang, Lijing, 2018
- Total Synthesis and Stereochemical Assignment of Gymnopeptides A and B, Pan, Zhengyin, Wu, Chunlei, Wang, Wei, Cheng, Zhehong, Yao, Guiyang, Liu, Ke, Li, Hongchang, Fang, Lijing, Su, Wu, 2017
- Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4, Shao, Ximing, Ding, Zhihao, Zhao, Ming, Liu, Ke, Sun, Haiyan, Chen, Juntao, Liu, Xianming, Zhang, Yuzhen, Hong, Yang, Li, Huashun, Li, Hongchang, 2017
- Numb positively regulates autophagic flux via regulating lysosomal function, Sun, Haiyan, Liu, Yi, Zhang, Lei, Shao, Ximing, Liu, Ke, Ding, Zhihao, Liu, Xianming, Jiang, Changan, Li, Huashun, Li, Hongchang, 2017
- Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4, Shao, Ximing, Ding, Zhihao, Zhao, Ming, Liu, Ke, Sun, Haiyan, Chen, Juntao, Liu, Xianming, Zhang, Yuzhen, Hong, Yang, Li, Huashun, Li, Hongchang, 2017
- NUMB negatively regulates the epithelial-mesenchymal transition of triple-negative breast cancer by antagonizing Notch signaling, Zhang, Jianchao, Shao, Ximing, Sun, Haiyan, Liu, Ke, Ding, Zhihao, Chen, Juntao, Fang, Lijing, Su, Wu, Hong, Yang, Li, Huashun, Li, Hongchang, 2016
- Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity, Liu, Ke, Lei, Run, Li, Qiong, Wang, XinXin, Wu, Qian, An, Peng, Zhang, Jianchao, Zhu, Minyan, Xu, Zhiheng, Hong, Yang, Wang, Fudi, Shen, Ying, Li, Hongchang, Li, Huashun, 2016
- G alpha s regulates asymmetric cell division of cortical progenitors by controlling Numb mediated Notch signaling suppression, Liu, Ke, Lin, Quan, Wei, Yanxia, He, Renbing, Shao, Ximing, Ding, Zhihao, Zhang, Jianchao, Zhu, Minyan, Weinstein, Lee S, Hong, Yang, Li, Hongchang, Li, Huashun, 2015
- G alpha(s) Relays Sphingosine-1-Phosphate Receptor 1 Signaling to Stabilize Vascular Endothelial-Cadherin at Endothelial Junctions to Control Mouse Embryonic Vascular Integrity, Shao, Ximing, Liu, Ke, Fan, Yi, Ding, Zhihao, Chen, Min, Zhu, Minyan, Weinstein, Lee S, Li, Hongchang, Li, Huashun, 2015
