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刘科
Life Science
中国科学院大学
广东
Language: 中文, 英语
天然多肽
抗肿瘤
高通量筛选
生物活性
分子靶点
仿生
人工多肽
癌症治疗
多肽合成
肿瘤靶向
Areas of Focus
- 高通量筛选具有抗肿瘤生物活性的天然多肽
- 寻找和鉴定新的抗肿瘤天然多肽分子靶点
- 设计合成仿生人工多肽分子，应用于抗肿瘤治疗
Academic Background & Achievements
- 2009-09 至 2014-06 理学博士: 四川大学，生物治疗国家重点实验室
- 2005-09 至 2009-07 理学学士: 四川大学，生命科学学院/吴玉章学院
Publications
- Coibamide A kills cancer cells through inhibiting autophagy, Shi, Wenli, Lu, Danyi, Wu, Chunlei, Li, Meiqing, Ding, Zhihao, Li, Yanyan, Chen, Binghua, Lin, Xian, Su, Wu, Shao, Ximing, Xia, Zhihui, Fang, Lijing, Liu, Ke, Li, Hongchang, 2021
- Novel N-Methylated Cyclodepsipeptide Prodrugs for Targeted Cancer Therapy, Wu, Chunlei, Cheng, Zhehong, Lu, Danyi, Liu, Ke, Cheng, Yulian, Wang, Pengxin, Zhou, Yimin, Li, Meiqing, Shao, Ximing, Li, Hongchang, Su, Wu, Fang, Lijing, 2021
- Aligned Biofunctional Electrospun PLGA-LysoGM1 Scaffold for Traumatic Brain Injury Repair, Tang, Wei, Fang, Fei, Ke, Liu, Huang, Zhi, Li, Hui, Yin, Ying, Wang, Jun, Wang, Guocheng, Wei, Liyu, Ou, Yun, Wang, Yazhou, 2020
- Clinical HDAC Inhibitors Are Effective Drugs to Prevent the Entry of SARS-CoV2, Liu, Ke, Zou, Rongfeng, Cui, Wenqiang, Li, Meiqing, Wang, Xueying, Dong, Junlin, Li, Hongchun, Li, Hongpei, Wang, Peihui, Shao, Ximing, Su, Wu, Chan, H C Stephen, Li, Hongchang, Yuan, Shuguang, 2020
- Chlorotoxin-derived bicyclic peptides for targeted imaging of glioblastomas, Li, Meiqing, Shao, Ximing, Wu, Chunlei, Lu, Danyi, Liu, Ke, Wang, Wei, Liu, Jiakai, Li, Hongchang, Su, Wu, Fang, Lijing, 2020
- Improved Total Synthesis and Biological Evaluation of Coibamide A Analogues, Yao, Guiyang, Wang, Wei, Ao, Lijiao, Cheng, Zhehong, Wu, Chunlei, Pang, Zhengyin, Liu, Ke, Li, Hongchang, Su, Wu, Fang, Lijing, 2018
- Targeting Polo-like Kinase 1 by a Novel Pyrrole-Imidazole Polyamide-Hoechst Conjugate Suppresses Tumor Growth In Vivo, Liu, Ke, Fang, Lijing, Sun, Haiyan, Pan, Zhengyin, Zhang, Jianchao, Chen, Juntao, Shao, Ximing, Wang, Wei, Tan, Yuanyan, Ding, Zhihao, Ao, Lijiao, Wu, Chunlei, Liu, Xiaoqi, Li, Huashun, Wang, Rui, Su, Wu, Li, Hongchang, 2018
- Polydopamine-Derivated Hierarchical Nanoplatforms for Efficient Dual-Modal Imaging-Guided Combination in Vivo Cancer Therapy, Ao, Lijiao, Wu, Chunlei, Liu, Ke, Wang, Wei, Fang, Lijing, Huang, Liang, Su, Wu, 2018
- Improved Total Synthesis and Biological Evaluation of Coibamide A Analogues, Yao, Guiyang, Wang, Wei, Ao, Lijiao, Cheng, Zhehong, Wu, Chunlei, Pang, Zhengyin, Liu, Ke, Li, Hongchang, Su, Wu, Fang, Lijing, 2018
- Total Synthesis and Stereochemical Assignment of Gymnopeptides A and B, Pan, Zhengyin, Wu, Chunlei, Wang, Wei, Cheng, Zhehong, Yao, Guiyang, Liu, Ke, Li, Hongchang, Fang, Lijing, Su, Wu, 2017
- Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4, Shao, Ximing, Ding, Zhihao, Zhao, Ming, Liu, Ke, Sun, Haiyan, Chen, Juntao, Liu, Xianming, Zhang, Yuzhen, Hong, Yang, Li, Huashun, Li, Hongchang, 2017
- Numb positively regulates autophagic flux via regulating lysosomal function, Sun, Haiyan, Liu, Yi, Zhang, Lei, Shao, Ximing, Liu, Ke, Ding, Zhihao, Liu, Xianming, Jiang, Changan, Li, Huashun, Li, Hongchang, 2017
- Mammalian Numb protein antagonizes Notch by controlling postendocytic trafficking of the Notch ligand Delta-like 4
