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Lang Rao
Life Science
University of Chinese Academy of Sciences
Tianjin
Language: English, Chinese
Protein Homeostasis
Autophagy
Proteasome
Protein Degradation
Cellular Balance
Epigenetic Editing
Histone Modification
Gene Regulation
Cell Engineering
Chassis Cell Development
Areas of Focus
- Regulation of Cellular Protein Homeostasis
- Development of Epigenetic Editing Techniques and Cell Modification
Work Experience
- 2021-03~Present - Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences - Associate Researcher
- 2020-01~2021-03 - VA Long Beach Healthcare System, Southern California Research and Education Institute - Research Scientist
- 2011-10~2019-12 - Baylor College of Medicine, Texas, USA - Postdoctoral Researcher
Academic Background & Achievements
- 2007-09--2011-08 PhD: Institute of Microbiology, Chinese Academy of Sciences
- 2004-09--2007-08 Master's: Jilin University
- 2000-09--2004-08 Bachelor's: Changchun Normal University
Publications
- α1-Antitrypsin—A Multifunctional Protein Resistant to SARS-CoV-2 Cell Invasion, Ye Xiao, Ling Xue, Lin Jiayu, Zhang Xiaoya, Zhang Ziyi, Rao Lang, 2023
- Laccase-mediated formation of hydrogels based on silk-elastin-like protein polymers with ultra-high molecular weight, Wang Sijia, Huang Wenxin, Feng Zhaoxuan, Tian Xiaoli, Wang Dexin, Rao Lang, Tan Ming, Roongsawang Niran, Song Hui, Jiang Wenxia, Bai Wenqin, 2023
- Improving Soluble Expression of SARS-CoV-2 Spike Priming Protease TMPRSS2 with an Artificial Fusing Protein, Ye Xiao, Ling Xue, Wu Min, Bai Guijie, Yuan Meng, Rao Lang, 2023
- Development of an Efficient C-to-T Base-Editing System and Its Application to Cellulase Transcription Factor Precise Engineering in Thermophilic Fungus Myceliophthora thermophila, Zhang Chenyang, Li Nan, Rao Lang, Li Jingen, Liu Qian, Tian Chaoguang, 2022
- p38 MAPK Activity Is Required to Prevent Hyperactivation of NLRP3 Inflammasome, Shin Jin Na, Rao Lang, Eissa N Tony, 2021
- A New Role Of The Proteasome In Alpha One Antitrypsin Regulation, Rao Lang, 2020
- Autophagy in Pulmonary Innate Immunity, Rao Lang, Eissa N Tony, 2020
- Pseudomonas aeruginosa survives in epithelia by ExoS‐mediated inhibition of autophagy and mTOR, Lang Rao, Indhira De La Rosa, Yi Xu, Youbao Sha, Abhisek Bhattacharya, Michael J Holtzman, Brian E Gilbert, N Tony Eissa, 2020
- Post-Transcriptional Regulation of Alpha One Antitrypsin by a Proteasome Inhibitor, Rao Lang, Xu Yi, Reineke Lucas Charles, Bhattacharya Abhisek, Tyryshkin Alexey, Shin Jin Na, Eissa N Tony, 2020
- The E3 ubiquitin ligase STUB1 regulates autophagy and mitochondrial biogenesis by modulating TFEB activity, Lang Rao, Youbao Sha, N Tony Eissa, 2017
- STUB1 regulates TFEB-induced autophagy-lysosome pathway, Sha Youbao, Rao Lang, Settembre Carmine, Ballabio Andrea, Eissa N Tony, 2017
- A Novel Alkaliphilic Bacillus Esterase Belongs to the 13th Bacterial Lipolytic Enzyme Family, Rao Lang, Xue Yanfen, Zheng Yingying, Lu Jian R, Ma Yanhe, 2013
- A thermostable esterase from Thermoanaerobacter tengcongensis opening up a new family of bacterial lipolytic enzymes, Rao Lang, Xue Yanfen, Zhou Cheng, Tao Jin, Li Gang, Lu Jian R, Ma Yanhe, 2011
- Comparative proteome analysis of alkaliphilic Bacillus sp.N16-5 grown on different carbon sources, LI Gang, SONG YaJian, XUE YanFen, RAO Lang, ZHOU Chen, WANG QuanHui, MA YanHe, 2011
- Comparative proteome analysis of alkaliphilic Bacillus sp N16-5 grown on different carbon sources, Li Gang, Song YaJian, Xue YanFen, Rao Lang, Zhou Chen, Wang QuanHui, Ma YanHe, 2011
- 嗜碱Bacillus sp.N16-5不同碳源条件下比较蛋白质组分析, 李刚, 宋亚囝, 薛艳芬, 饶朗, 周成, 王全会, 马延和, 2010
- Cloning, Expression, and Characterization of a Highly Active Alkaline Pectate Lyase from Alkaliphilic Bacillus sp N16-5, Li Gang, Rao Lang, Xue Yanfen, Zhou Cheng, Zhang Yun, Ma Yanhe, 2010
- Solution Behavior and Activity of a Halophilic Esterase under High Salt Concentration, Rao Lang, Zhao Xiubo, Pan Fang, Li Yin, Xue Yanfen, Ma Yanhe, Lu Jian R, 2009
- Study on a Specific Site Tyr(444) on a Hyperthermophilic Enzyme APE1547, Rao Lang, Bi Yunfeng, Xie Guiqiu, Zhang Fei, Wang Yan, Cao Shugui, Gao Renjun, 2009
- High-throughput screening of the enantioselectivity of hyperthermophilic mutant esterases from Archaeon Aeropyrum pernix K1 for resolution of (R, S)-2-octanol acetate, Zhang Guirong, Gao Renjun, Zhang Aijun, Rao Lang, Cao Shugui, 2007
