Areas of Focus
- Lipid Metabolism Regulation
- Metabolomics
- Proteomics
- Fermentation Engineering
Work Experience
- 2023-01~Present - Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences - Researcher
- 2013-01~2022-12 - Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences - Associate Researcher
- 2010-06~2012-12 - Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences - Assistant Researcher
- 2008-08~2010-06 - Ocean University of China - Postdoctoral
Academic Background & Achievements
- 2003-09--2008-07 PhD: Ocean University of China
- 1999-09--2003-07 Bachelor's: Ocean University of China
- Published over 40 papers
- Received 23 authorized Chinese invention patents
Publications
- A high-throughput platform enables in situ screening of fatty acid-producing strains using laser ablation electrospray ionization mass spectrometry and a Python package, TALANTA, 2024
- Modular Metabolic Engineering of Mortierella alpina by the 2A Peptide Platform to Improve Arachidonic Acid Production, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2023
- Application of Microalgae in Water Purification of Aquaculture, 浙江海洋大学学报:自然科学版, 2023
- A phospholipid:diacylglycerol acyltransferase is involved in the regulation of phospholipids homeostasis in oleaginous Aurantiochytrium sp., BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS, 2023
- Dissolved xylan inhibits cellulosome-based saccharification by binding to the key cellulosomal component of Clostridium thermocellum, International Journal of Biological Macromolecules, 2022
- 碳离子束诱变选育高产角鲨烯类酵母及电转化初探, 南方水产科学, 2022
- A Two-Stage Adaptive Laboratory Evolution Strategy to Enhance Docosahexaenoic Acid Synthesis in Oleaginous Thraustochytrid, FRONTIERS IN NUTRITION, 2021
- Sustainable development of microalgal biotechnology in coastal zone for aquaculture and food, SCIENCE OF THE TOTAL ENVIRONMENT, 2021
- Research advances on arachidonic acid production by fermentation and genetic modification of Mortierella alpina, WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY, 2021
- Obtaining High-Purity Docosahexaenoic Acid Oil in Thraustochytrid Aurantiochytrium through a Combined Metabolic Engineering Strategy, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2021
- Cocktail biosynthesis of triacylglycerol by rational modulation of diacylglycerol acyltransferases in industrial oleaginous Aurantiochytrium, BIOTECHNOLOGY FOR BIOFUELS, 2021
- PUFA-synthase-specific PPTase enhanced the polyunsaturated fatty acid biosynthesis via the polyketide synthase pathway in Aurantiochytrium, BIOTECHNOLOGY FOR BIOFUELS, 2020
- Improving lipid productivity by engineering a control-knob gene in the oleaginous microalga Nannochloropsis oceanica, METABOLIC ENGINEERING COMMUNICATIONS, 2020
- Comprehensive analysis of metabolic alterations in Schizochytrium sp. strains with different DHA content, JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2020
- Optimizing Eicosapentaenoic Acid Production by Grafting a Heterologous Polyketide Synthase Pathway in the Thraustochytrid Aurantiochytrium, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2020
- Changes in peptidomes and Fischer ratios of corn-derived oligopeptides depending on enzyme hydrolysis approaches, FOOD CHEMISTRY, 2019
- Enhancing tricarboxylate transportation-related NADPH generation to improve biodiesel production by Aurantiochytrium, ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2019
- Phytohormones as stimulators to improve arachidonic acid biosynthesis in Mortierella alpina, ENZYMEANDMICROBIALTECHNOLOGY, 2019
- Enhancing tricarboxylate transportation-related NADPH generation to improve biodiesel production by Aurantiochytrium, ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2019
- Improvement of the eicosapentaenoic acid yield in Nannochloropsis using a new breeding strategy, 发酵科技通讯, 2018
- Heavy ion mutagenesis combined with triclosan screening provides a new strategy for improving the arachidonic acid yield in Mortierella alpina, BMC BIOTECHNOLOGY, 2018
- Artificial creation of Chlorella pyrenoidosa mutants for economic sustainable food production, BIORESOURCE TECHNOLOGY, 2018
- Effects of plant hormones on the lipid and eicosapentaenoic acid production in Nannochloropsis, 发酵科技通讯, 2018
- Wastewater recycling technology for fermentation in polyunsaturated fatty acid production, BIORESOURCE TECHNOLOGY, 2017
- Response mechanism of the docosahexaenoic acid producer Aurantiochytrium under cold stress, ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2017
- Expression of Vitreoscilla hemoglobin enhances production of arachidonic acid and lipids in Mortierella alpina, BMC BIOTECHNOLOGY, 2017
- Response mechanism of the docosahexaenoic acid producer Aurantiochytrium under cold stress, ALGALRESEARCH, 2017
- Overexpression of glucose-6-phosphate dehydrogenase enhanced the polyunsaturated fatty acid composition of Aurantiochytrium sp. SD116, ALGAL RESEARCH, 2016
- A new strategy for strain improvement of Aurantiochytrium sp. based on heavy-ions mutagenesis and synergistic effects of cold stress and inhibitors of enoyl-ACP reductase, ENZYME AND MICROBIAL TECHNOLOGY, 2016
- High production of squalene using a newly isolated yeast-like strain Pseudozyma sp. SD301, INTERNATIONAL NEWS ON FATS, OILS AND RELATED MATERIALS : INFORM, 2016
- Overexpression of glucose-6-phosphate dehydrogenase enhanced the polyunsaturated fatty acid composition of Aurantiochytrium sp SD116, ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 2016
- Optimization of Fermentation Conditions for Squalene Production by Marine Microbe Using Response Surface Methodology, 中国海洋大学学报(自然科学版), 2016
- High Production of Squalene Using a Newly Isolated Yeast-like Strain Pseudozyma sp SD301, JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2015
- Transcriptome and gene expression analysis of DHA producer Aurantiochytrium under low temperature conditions, SCIENTIFIC REPORTS, 2015
- Production of High Docosahexaenoic Acid by Schizochytrium sp Using Low-cost Raw Materials from Food Industry, JOURNALOFOLEOSCIENCE, 2015
- 利用伯克霍尔德氏菌脂肪酶富集裂壶藻油脂中的二十二碳六烯酸, 食品科学, 2015
- 利用伯克霍尔德氏菌脂肪酶富集裂壶藻油脂中的DHA, 食品科学, 2014
- 裂殖壶菌OUC88 及10 个派生菌株18S rDNA 基因克隆和分析., 海洋科学, 2014
Awards
- China Food Industry Association Science and Technology Award, First Prize, 2023
- Qinghai Province Kunlun Talents - Top Talent, Special Prize, 2021
- Qingdao Youth Science and Technology Award, Special Prize, 2018
- Chinese Academy of Sciences Shenyang Branch Fifth Excellent Scientific Talent Award, Special Prize, 2017
- Qingdao Science and Technology Progress Award, Third Prize, 2016
- Shandong Science and Technology Award, Second Prize, 2015
- Science and Technology Commissioner Rural Science and Technology Innovation and Entrepreneurship Competition, Second Prize, 2010