Professor | Huarong Tan | Asia Growth Partners

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Name	Huarong Tan
Contact Information	tanhr@im.ac.cn
Language ability	Chinese, English
Province	Beijing

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Name

Huarong Tan

Contact Information

tanhr@im.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences
Academic Background & Achievements	Graduate - PhD 1994: First batch selected for Chinese Academy of Sciences 1995: Approved as Doctoral Supervisor 1999: Received National Outstanding Youth Science Fund
Work Experience	1978-09 to 1985-09 - Institute of Microbiology, Chinese Academy of Sciences - Intern Researcher 1985-10 to 1986-10 - Osaka University, Japan - Research on small molecule compounds 1986-10 to 1988-10 - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher 1991-12 to 1993-07 - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher 1994-01 to Present - Institute of Microbiology, Chinese Academy of Sciences - Researcher
Awards	1994: First batch selected for Chinese Academy of Sciences 1995: Approved as Doctoral Supervisor 1999: Received National Outstanding Youth Science Fund

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Academic Background & Achievements

Graduate - PhD
1994: First batch selected for Chinese Academy of Sciences
1995: Approved as Doctoral Supervisor
1999: Received National Outstanding Youth Science Fund

Work Experience

1978-09 to 1985-09 - Institute of Microbiology, Chinese Academy of Sciences - Intern Researcher
1985-10 to 1986-10 - Osaka University, Japan - Research on small molecule compounds
1986-10 to 1988-10 - Institute of Microbiology, Chinese Academy of Sciences - Assistant Researcher
1991-12 to 1993-07 - Institute of Microbiology, Chinese Academy of Sciences - Associate Researcher
1994-01 to Present - Institute of Microbiology, Chinese Academy of Sciences - Researcher

Awards

1994: First batch selected for Chinese Academy of Sciences
1995: Approved as Doctoral Supervisor
1999: Received National Outstanding Youth Science Fund

Areas of Focus	Gene expression and molecular mechanisms in Streptomyces development and differentiation Biosynthetic pathways and regulation of microbial secondary metabolism
Publications	Autoregulation of antibiotic biosynthesis by binding of the end product to an atypical response regulator, Linqi Wang, Xiuyun Tian, Juan Wang, Haihua Yang, Keqiang Fan, Gangming Xu, Keqian Yang, Huarong Tan, 2009 A pathway-specific transcriptional regulatory gene for nikkomycin biosynthesis in S. ansochromogenes that also influences colony development, Gang Liu, Yuqing Tian, Haihua Yang, Huarong Tan, 2005 The tyrosine degradation gene hppD is transcriptionally activated by HpdA and repressed by HpdR in Streptomyces coelicolor, while hpdA is negatively autoregulated and repressed by HpdR, Haihua Yang, Linqi Wang, Zhoujie Xie, Yuqing Tian, Gang Liu, Huarong Tan, 2007 The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis in Streptomyces ansochromogenes, Yuanyuan Pan, Gang Liu, Haihua Yang, Yuqing Tian, Huarong Tan, 2009 PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi, Rui Li, Gang Liu, Zhoujie Xie, Xihong He, Wenqing Chen, Zixin Deng, Huarong Tan, 2010 Pseudo gamma-butyrolactone receptors respond to antibiotic signals to coordinate antibiotics biosynthesis, Gangming Xu, Juan Wang, Linqi Wang, Xiuyun Tian, Haihua Yang, Keqiang Fan, Keqian Yang, Huarong Tan, 2010 SanJ, an ATP-dependent picolinate-CoA ligase, catalyzes the conversion of picolinate to picolinate-CoA during nikkomycin biosynthesis in S. ansochromogenes, Guoqing Niu, Gang Liu, Yuqing Tian, Huarong Tan, 2006 Improvement of nikkomycin production by enhanced copy of sanU and sanV in Streptomyces ansochromogenes and characterization of a novel glutamate mutase encoded by sanU and sanV, Yirong Li, Hongbo Ling, Wenli Li, Huarong Tan, 2005 Characterization of EndoTT, a novel sequence-specific single-stranded DNA endonuclease from Thermoanaerobacter tengcongensis, Shuli Zhang, Bo Liu, Haihua Yang, Yuqing Tian, Gang Liu, Lei Li, Huarong Tan, 2010 A complete sequence of the Thermoanaerobacter tengcongensis genome, Qiyu Bao, Yuqing Tian, Wei Li, Zuyuan Xu, Zhenyu Xuan, Songnian Hu, Wei Dong, Jian Yang, Yanjiong Chen, Yanfen Xue, Yi Xu, Xiaoqin Lai, Li Huang, Xiuzhu Dong, Yanhe Ma, Lunjiang Ling, Huarong Tan, Runsheng Chen, Jian Wang, Jun Yu, Huanming Yang, 2002

Areas of Focus

Gene expression and molecular mechanisms in Streptomyces development and differentiation
Biosynthetic pathways and regulation of microbial secondary metabolism

Publications

Autoregulation of antibiotic biosynthesis by binding of the end product to an atypical response regulator, Linqi Wang, Xiuyun Tian, Juan Wang, Haihua Yang, Keqiang Fan, Gangming Xu, Keqian Yang, Huarong Tan, 2009
A pathway-specific transcriptional regulatory gene for nikkomycin biosynthesis in S. ansochromogenes that also influences colony development, Gang Liu, Yuqing Tian, Haihua Yang, Huarong Tan, 2005
The tyrosine degradation gene hppD is transcriptionally activated by HpdA and repressed by HpdR in Streptomyces coelicolor, while hpdA is negatively autoregulated and repressed by HpdR, Haihua Yang, Linqi Wang, Zhoujie Xie, Yuqing Tian, Gang Liu, Huarong Tan, 2007
The pleiotropic regulator AdpA-L directly controls the pathway-specific activator of nikkomycin biosynthesis in Streptomyces ansochromogenes, Yuanyuan Pan, Gang Liu, Haihua Yang, Yuqing Tian, Huarong Tan, 2009
PolY, a transcriptional regulator with ATPase activity, directly activates transcription of polR in polyoxin biosynthesis in Streptomyces cacaoi, Rui Li, Gang Liu, Zhoujie Xie, Xihong He, Wenqing Chen, Zixin Deng, Huarong Tan, 2010
Pseudo gamma-butyrolactone receptors respond to antibiotic signals to coordinate antibiotics biosynthesis, Gangming Xu, Juan Wang, Linqi Wang, Xiuyun Tian, Haihua Yang, Keqiang Fan, Keqian Yang, Huarong Tan, 2010
SanJ, an ATP-dependent picolinate-CoA ligase, catalyzes the conversion of picolinate to picolinate-CoA during nikkomycin biosynthesis in S. ansochromogenes, Guoqing Niu, Gang Liu, Yuqing Tian, Huarong Tan, 2006
Improvement of nikkomycin production by enhanced copy of sanU and sanV in Streptomyces ansochromogenes and characterization of a novel glutamate mutase encoded by sanU and sanV, Yirong Li, Hongbo Ling, Wenli Li, Huarong Tan, 2005
Characterization of EndoTT, a novel sequence-specific single-stranded DNA endonuclease from Thermoanaerobacter tengcongensis, Shuli Zhang, Bo Liu, Haihua Yang, Yuqing Tian, Gang Liu, Lei Li, Huarong Tan, 2010
A complete sequence of the Thermoanaerobacter tengcongensis genome, Qiyu Bao, Yuqing Tian, Wei Li, Zuyuan Xu, Zhenyu Xuan, Songnian Hu, Wei Dong, Jian Yang, Yanjiong Chen, Yanfen Xue, Yi Xu, Xiaoqin Lai, Li Huang, Xiuzhu Dong, Yanhe Ma, Lunjiang Ling, Huarong Tan, Runsheng Chen, Jian Wang, Jun Yu, Huanming Yang, 2002

Streptomyces Gene Expression Molecular Mechanisms Development Differentiation Secondary Metabolism Biosynthesis Regulation Microbial Antibiotics

Yinhua Lu - Shanghai Normal University

Hua Yuan - Shanghai Normal University

Xiaobin Wu - Shanghai Normal University

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