Professor | Feng Wang | Asia Growth Partners

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Name	Feng Wang
Contact Information	wangfeng@ibp.ac.cn
Language ability	Chinese, English
Province	Beijing

Upload Avatar (500 x 500)

Name

Feng Wang

Contact Information

wangfeng@ibp.ac.cn

Language ability

Chinese, English

Province

Beijing

University/Lab Affiliation and Title	University of Chinese Academy of Sciences
Faculty	Life Sciences

University/Lab Affiliation and Title

University of Chinese Academy of Sciences

Faculty

Life Sciences

Areas of Focus	Antibody Engineering Chemical Biology Biophysics Pharmacology Immunology Protein Engineering Therapeutic Antibodies Molecular Biology Biotechnology Drug Development
Publications	Site-specific Conjugation of a Selenopolypeptide to Alpha-1-antitrypsin Enhances Oxidation Resistance and Pharmacological Properties, Dong C, Wu GQ, Chen C, Li X, Yuan R, Xu L, Guo H, Zhang J, Lu H, Wang F, 2021 Epitope-directed antibody selection by site-specific photocrosslinking, Chen, Longxin, Zhu, Chaoyang, Guo, Hui, Li, Runting, Zhang, Limeng, Xing, Zhenzhen, Song, Yue, Zhang, Zihan, Wang, Fuping, Liu, Xiaofeng, Zhang, Yuhan, Ma, Runlin Z, Wang, Feng, 2020 Functional genetic encoding of sulfotyrosine in mammalian cells, Xinyuan He, Yan Chen, Daisy Guiza Beltran, Maia Kelly, Bin Ma, Justin Lawrie, Feng Wang, Eric Dodds, Limei Zhang, Jiantao Guo, Wei Niu, 2020 Complete genome of a unicellular parasite (Antonospora locustae) and transcriptional interactions with its host locust, Chen, Longxin, Gao, Xingke, Li, Runting, Zhang, Limeng, Huang, Rui, Wang, Linqing, Song, Yue, Xing, Zhenzhen, Liu, Ting, Nie, Xiaoning, Nie, Fangyuan, Hua, Shuang, Zhang, Zihan, Wang, Feng, Ma, Runlin Z, Zhang, Long, 2020 A tumor-targeted immune checkpoint blocker, Zhang, Yuhan, Fang, Changming, Wang, Rongsheng E, Wang, Ying, Guo, Hui, Guo, Chao, Zhao, Lijun, Li, Shuhong, Li, Xia, Schultz, Peter G, Cao, Yu J, Wang, Feng, 2019 Animal protein toxins: origins and therapeutic applications, Chen Na, Xu Siqi, Zhang Yuhan, Wang Feng, 2018 Small Molecules Targeting Mycobacterium tuberculosis Type II NADH Dehydrogenase Exhibit Antimycobacterial Activity, Harbut, Michael B, Yang, Baiyuan, Liu, Renhe, Yano, Takahiro, Vilcheze, Catherine, Cheng, Bo, Lockner, Jonathan, Guo, Hui, Yu, Chenguang, Franzblau, Scott G, Petrassi, H Mike, Jacobs, William R, Jr, Rubin, Harvey, Chatterjee, Arnab K, Wang, Feng, 2018 Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes, Liu R, 2017 Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria, Luo, Xiaozhou, Fu, Guangsen, Wang, Rongsheng E, Zhu, Xueyong, Zambaldo, Claudio, Liu, Renhe, Liu, Tao, Lyu, Xiaoxuan, Du, Jintang, Xuan, Weimin, Yao, Anzhi, Reed, Sean A, Kang, Mingchao, Zhang, Yuhan, Guo, Hui, Huang, Chunhui, Yang, PengYu, Wilson, Ian A, Schultz, Peter G, Wang, Feng, 2017 Engineering Bifunctional Antibodies with Constant Region Fusion Architectures, Du, Juanjuan, Cao, Yu, Liu, Yan, Wang, Ying, Zhang, Yong, Fu, Guangsen, Zhang, Yuhan, Lu, Lucy, Luo, Xiaozhou, Kim, Chan Hyuk, Schultz, Peter G, Wang, Feng, 2017 Multifunctional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon, and Glucose-Dependent Insulinotropic Polypeptide Receptors, Wang, Ying, Du, Jintang, Zou, Huafei, Liu, Yan, Zhang, Yuhan, Gonzalez, Jose, Chao, Elizabeth, Lu, Lucy, Yang, Pengyu, Parker, Holly, Van NguyenTran, Shen, Weijun, Wang, Danling, Schultz, Peter G, Wang, Feng, 2016 Rational Design of Dual Agonist-Antibody Fusions as Long-acting Therapeutic Hormones, Liu, Yan, Wang, Ying, Zhang, Yong, Liu, Tao, Jia, Haiqun, Zou, Huafei, Fu, Qiangwei, Zhang, Yuhan, Lu, Lucy, Chao, Elizabeth, Parker, Holly, NguyenTran, Van, Shen, Weijun, Wang, Danling, Schultz, Peter G, Wang, Feng, 2016 Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant, Wang, Rongsheng E, Wang, Ying, Zhang, Yuhan, Gabrelow, Chase, Zhang, Yong, Chi, Victor, Fu, Qiangwei, Luo, Xiaozhou, Wang, Danling, Joseph, Sean, Johnson, Kristen, Chatterjee, Arnab K, Wright, Timothy M, NguyenTran, Van T B, Teijaro, John, Theofilopoulos, Argyrios N, Schultz, Peter G, Wang, Feng, 2016 Functional human antibody CDR fusions as long-acting therapeutic endocrine agonists, Liu, Tao, Zhang, Yong, Liu, Yan, Wang, Ying, Jia, Haiqun, Kang, Mingchao, Luo, Xiaozhou, Caballero, Dawna, Gonzalez, Jose, Sherwood, Lance, Nunez, Vanessa, Wang, Danling, Woods, Ashley, Schultz, Peter G, Wang, Feng, 2015 Rational Design of Humanized Dual-Agonist Antibodies, Zhang, Yong, Liu, Yan, Wang, Ying, Schultz, Peter G, Wang, Feng, 2015 Rational Design of Antibody Protease Inhibitors, Liu, Tao, Fu, Guangsen, Luo, Xiaozhou, Liu, Yan, Wang, Ying, Wang, Rongsheng E, Schultz, Peter G, Wang, Feng, 2015 Rational Design of a Humanized Glucagon-Like Peptide-1 Receptor Agonist Antibody, Zhang, Yong, Zou, Huafei, Wang, Ying, Caballero, Dawna, Gonzalez, Jose, Chao, Elizabeth, Welzel, Gus, Shen, Weijun, Wang, Danling, Schultz, Peter G, Wang, Feng, 2015 Homogeneously modified immunoglobulin domains for therapeutic application, Liu, Tao, Du, Juanjuan, Luo, Xiaozhou, Schultz, Peter G, Wang, Feng, 2015 An Immunosuppressive Antibody-Drug Conjugate, Wang, Rongsheng E, Liu, Tao, Wang, Ying, Cao, Yu, Du, Jintang, Luo, Xiaozhou, Deshmukh, Vishal, Kim, Chan Hyuk, Lawson, Brian R, Tremblay, Matthew S, Young, Travis S, Kazane, Stephanie A, Wang, Feng, Schultz, Peter G, 2015 Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis, Harbut, Michael B, Vilcheze, Catherine, Luo, Xiaozhou, Hensler, Mary E, Guo, Hui, Yang, Baiyuan, Chatterjee, Arnab K, Nizet, Victor, Jacobs, William R, Jr, Schultz, Peter G, Wang, Feng, 2015 An Antibody with a Variable-Region Coiled-Coil 'Knob' Domain, Zhang, Yong, Goswami, Devrishi, Wang, Danling, Wang, TsungShing Andrew, Sen, Shiladitya, Magliery, Thomas J, Griffin, Patrick R, Wang, Feng, Schultz, Peter G, 2014 Rational Design of CXCR4 Specific Antibodies with Elongated CDRs, Liu, Tao, Liu, Yan, Wang, Ying, Hull, Mitchell, Schultz, Peter G, Wang, Feng, 2014 Reshaping Antibody Diversity, Wang, Feng, Ekiert, Damian C, Ahmad, Insha, Yu, Wenli, Zhang, Yong, Bazirgan, Omar, Torkamani, Ali, Raudsepp, Terje, Mwangi, Waithaka, Criscitiello, Michael F, Wilson, Ian A, Schultz, Peter G, Smider, Vaughn V, 2013 An Antibody CDR3-Erythropoietin Fusion Protein, Zhang, Yong, Wang, Danling, Welzel, Gus, Wang, Ying, Schultz, Peter G, Wang, Feng, 2013 Correction for Wang et al., Identification of a small molecule with activity against drug-resistant and persistent tuberculosis, Not mentioned, 2013 Functional Antibody CDR3 Fusion Proteins with Enhanced Pharmacological Properties, Zhang, Yong, Wang, Danling, de Lichtervelde, Lorenzo, Sun, Sophie B, Smider, Vaughn V, Schultz, Peter G, Wang, Feng, 2013 Structural and functional insights into lipid-bound nerve growth factors, Tong, Qiong, Wang, Feng, Zhou, HongZhe, Sun, HanLi, Song, Hui, Shu, YuYan, Gong, Yong, Zhang, WenTing, Cai, Tanxi, Yang, FuQuan, Tang, Jie, Jiang, Tao, 2012 Crystallization and preliminary X-ray diffraction analysis of three mastoparans, Wang, Feng, Liu, Xiaoqin, Li, He, Lang, Xianjun, Peng, Hui, Liu, Shenquan, Jiang, Tao, 2006 An Epitope-Specific Respiratory Syncytial Virus Vaccine based on an Antibody Scaffold, Luo Xiaozhou, Liu Tao Dr., Wang Ying Dr., Jia Haiqun Dr., Zhang Yuhan, Caballero Dawna, Du Juanjuan Dr., Wang Rongsheng E. Dr., Wang Danling Dr., Schultz Peter G., Wang Feng Dr., 2013

Areas of Focus

Antibody Engineering
Chemical Biology
Biophysics
Pharmacology
Immunology
Protein Engineering
Therapeutic Antibodies
Molecular Biology
Biotechnology
Drug Development

Publications

Site-specific Conjugation of a Selenopolypeptide to Alpha-1-antitrypsin Enhances Oxidation Resistance and Pharmacological Properties, Dong C, Wu GQ, Chen C, Li X, Yuan R, Xu L, Guo H, Zhang J, Lu H, Wang F, 2021
Epitope-directed antibody selection by site-specific photocrosslinking, Chen, Longxin, Zhu, Chaoyang, Guo, Hui, Li, Runting, Zhang, Limeng, Xing, Zhenzhen, Song, Yue, Zhang, Zihan, Wang, Fuping, Liu, Xiaofeng, Zhang, Yuhan, Ma, Runlin Z, Wang, Feng, 2020
Functional genetic encoding of sulfotyrosine in mammalian cells, Xinyuan He, Yan Chen, Daisy Guiza Beltran, Maia Kelly, Bin Ma, Justin Lawrie, Feng Wang, Eric Dodds, Limei Zhang, Jiantao Guo, Wei Niu, 2020
Complete genome of a unicellular parasite (Antonospora locustae) and transcriptional interactions with its host locust, Chen, Longxin, Gao, Xingke, Li, Runting, Zhang, Limeng, Huang, Rui, Wang, Linqing, Song, Yue, Xing, Zhenzhen, Liu, Ting, Nie, Xiaoning, Nie, Fangyuan, Hua, Shuang, Zhang, Zihan, Wang, Feng, Ma, Runlin Z, Zhang, Long, 2020
A tumor-targeted immune checkpoint blocker, Zhang, Yuhan, Fang, Changming, Wang, Rongsheng E, Wang, Ying, Guo, Hui, Guo, Chao, Zhao, Lijun, Li, Shuhong, Li, Xia, Schultz, Peter G, Cao, Yu J, Wang, Feng, 2019
Animal protein toxins: origins and therapeutic applications, Chen Na, Xu Siqi, Zhang Yuhan, Wang Feng, 2018
Small Molecules Targeting Mycobacterium tuberculosis Type II NADH Dehydrogenase Exhibit Antimycobacterial Activity, Harbut, Michael B, Yang, Baiyuan, Liu, Renhe, Yano, Takahiro, Vilcheze, Catherine, Cheng, Bo, Lockner, Jonathan, Guo, Hui, Yu, Chenguang, Franzblau, Scott G, Petrassi, H Mike, Jacobs, William R, Jr, Rubin, Harvey, Chatterjee, Arnab K, Wang, Feng, 2018
Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes, Liu R, 2017
Genetically encoding phosphotyrosine and its nonhydrolyzable analog in bacteria, Luo, Xiaozhou, Fu, Guangsen, Wang, Rongsheng E, Zhu, Xueyong, Zambaldo, Claudio, Liu, Renhe, Liu, Tao, Lyu, Xiaoxuan, Du, Jintang, Xuan, Weimin, Yao, Anzhi, Reed, Sean A, Kang, Mingchao, Zhang, Yuhan, Guo, Hui, Huang, Chunhui, Yang, PengYu, Wilson, Ian A, Schultz, Peter G, Wang, Feng, 2017
Engineering Bifunctional Antibodies with Constant Region Fusion Architectures, Du, Juanjuan, Cao, Yu, Liu, Yan, Wang, Ying, Zhang, Yong, Fu, Guangsen, Zhang, Yuhan, Lu, Lucy, Luo, Xiaozhou, Kim, Chan Hyuk, Schultz, Peter G, Wang, Feng, 2017
Multifunctional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon, and Glucose-Dependent Insulinotropic Polypeptide Receptors, Wang, Ying, Du, Jintang, Zou, Huafei, Liu, Yan, Zhang, Yuhan, Gonzalez, Jose, Chao, Elizabeth, Lu, Lucy, Yang, Pengyu, Parker, Holly, Van NguyenTran, Shen, Weijun, Wang, Danling, Schultz, Peter G, Wang, Feng, 2016
Rational Design of Dual Agonist-Antibody Fusions as Long-acting Therapeutic Hormones, Liu, Yan, Wang, Ying, Zhang, Yong, Liu, Tao, Jia, Haiqun, Zou, Huafei, Fu, Qiangwei, Zhang, Yuhan, Lu, Lucy, Chao, Elizabeth, Parker, Holly, NguyenTran, Van, Shen, Weijun, Wang, Danling, Schultz, Peter G, Wang, Feng, 2016
Rational design of a Kv1.3 channel-blocking antibody as a selective immunosuppressant, Wang, Rongsheng E, Wang, Ying, Zhang, Yuhan, Gabrelow, Chase, Zhang, Yong, Chi, Victor, Fu, Qiangwei, Luo, Xiaozhou, Wang, Danling, Joseph, Sean, Johnson, Kristen, Chatterjee, Arnab K, Wright, Timothy M, NguyenTran, Van T B, Teijaro, John, Theofilopoulos, Argyrios N, Schultz, Peter G, Wang, Feng, 2016
Functional human antibody CDR fusions as long-acting therapeutic endocrine agonists, Liu, Tao, Zhang, Yong, Liu, Yan, Wang, Ying, Jia, Haiqun, Kang, Mingchao, Luo, Xiaozhou, Caballero, Dawna, Gonzalez, Jose, Sherwood, Lance, Nunez, Vanessa, Wang, Danling, Woods, Ashley, Schultz, Peter G, Wang, Feng, 2015
Rational Design of Humanized Dual-Agonist Antibodies, Zhang, Yong, Liu, Yan, Wang, Ying, Schultz, Peter G, Wang, Feng, 2015
Rational Design of Antibody Protease Inhibitors, Liu, Tao, Fu, Guangsen, Luo, Xiaozhou, Liu, Yan, Wang, Ying, Wang, Rongsheng E, Schultz, Peter G, Wang, Feng, 2015
Rational Design of a Humanized Glucagon-Like Peptide-1 Receptor Agonist Antibody, Zhang, Yong, Zou, Huafei, Wang, Ying, Caballero, Dawna, Gonzalez, Jose, Chao, Elizabeth, Welzel, Gus, Shen, Weijun, Wang, Danling, Schultz, Peter G, Wang, Feng, 2015
Homogeneously modified immunoglobulin domains for therapeutic application, Liu, Tao, Du, Juanjuan, Luo, Xiaozhou, Schultz, Peter G, Wang, Feng, 2015
An Immunosuppressive Antibody-Drug Conjugate, Wang, Rongsheng E, Liu, Tao, Wang, Ying, Cao, Yu, Du, Jintang, Luo, Xiaozhou, Deshmukh, Vishal, Kim, Chan Hyuk, Lawson, Brian R, Tremblay, Matthew S, Young, Travis S, Kazane, Stephanie A, Wang, Feng, Schultz, Peter G, 2015
Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis, Harbut, Michael B, Vilcheze, Catherine, Luo, Xiaozhou, Hensler, Mary E, Guo, Hui, Yang, Baiyuan, Chatterjee, Arnab K, Nizet, Victor, Jacobs, William R, Jr, Schultz, Peter G, Wang, Feng, 2015
An Antibody with a Variable-Region Coiled-Coil 'Knob' Domain, Zhang, Yong, Goswami, Devrishi, Wang, Danling, Wang, TsungShing Andrew, Sen, Shiladitya, Magliery, Thomas J, Griffin, Patrick R, Wang, Feng, Schultz, Peter G, 2014
Rational Design of CXCR4 Specific Antibodies with Elongated CDRs, Liu, Tao, Liu, Yan, Wang, Ying, Hull, Mitchell, Schultz, Peter G, Wang, Feng, 2014
Reshaping Antibody Diversity, Wang, Feng, Ekiert, Damian C, Ahmad, Insha, Yu, Wenli, Zhang, Yong, Bazirgan, Omar, Torkamani, Ali, Raudsepp, Terje, Mwangi, Waithaka, Criscitiello, Michael F, Wilson, Ian A, Schultz, Peter G, Smider, Vaughn V, 2013
An Antibody CDR3-Erythropoietin Fusion Protein, Zhang, Yong, Wang, Danling, Welzel, Gus, Wang, Ying, Schultz, Peter G, Wang, Feng, 2013
Correction for Wang et al., Identification of a small molecule with activity against drug-resistant and persistent tuberculosis, Not mentioned, 2013
Functional Antibody CDR3 Fusion Proteins with Enhanced Pharmacological Properties, Zhang, Yong, Wang, Danling, de Lichtervelde, Lorenzo, Sun, Sophie B, Smider, Vaughn V, Schultz, Peter G, Wang, Feng, 2013
Structural and functional insights into lipid-bound nerve growth factors, Tong, Qiong, Wang, Feng, Zhou, HongZhe, Sun, HanLi, Song, Hui, Shu, YuYan, Gong, Yong, Zhang, WenTing, Cai, Tanxi, Yang, FuQuan, Tang, Jie, Jiang, Tao, 2012
Crystallization and preliminary X-ray diffraction analysis of three mastoparans, Wang, Feng, Liu, Xiaoqin, Li, He, Lang, Xianjun, Peng, Hui, Liu, Shenquan, Jiang, Tao, 2006
An Epitope-Specific Respiratory Syncytial Virus Vaccine based on an Antibody Scaffold, Luo Xiaozhou, Liu Tao Dr., Wang Ying Dr., Jia Haiqun Dr., Zhang Yuhan, Caballero Dawna, Du Juanjuan Dr., Wang Rongsheng E. Dr., Wang Danling Dr., Schultz Peter G., Wang Feng Dr., 2013

Antibody Engineering Chemical Biology Biophysics Pharmacology Immunology Protein Therapeutic Development

Gao Feng - University of Chinese Academy of Sciences

Xiao Haixia - University of Chinese Academy of Sciences

Li Jie - Nanjing University

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