Professor | Li Jie | Asia Growth Partners

	Upload Avatar (500 x 500)
Name	Li Jie
Language ability	Chinese, English
Province	Jiangsu

Upload Avatar (500 x 500)

Name

Li Jie

Language ability

Chinese, English

Province

Jiangsu

University/Lab Affiliation and Title	Nanjing University
Faculty	Life Sciences
Academic Background & Achievements	2006-2010 Bachelor: Wuhan University, Chemistry 2010-2015 PhD: Peking University, Chemical Biology
Work Experience	2015-2018 Postdoctoral Researcher: Scripps Research Institute, Chemistry and Molecular Pharmacology 2019-present Professor: Nanjing University, School of Chemistry and Chemical Engineering 2019-present Principal Investigator: Nanjing University, Institute of Chemistry and Biomedical Innovation
Awards	2022: Member of the National Huang Danian-style Faculty Team 2020: National Overseas High-Level Young Talent 2020: Second Prize of National Natural Science Award (Fourth Contributor) 2019: Jiangsu Distinguished Professor 2019: First Prize of Ministry of Education Natural Science Award (Fourth Contributor)

University/Lab Affiliation and Title

Nanjing University

Faculty

Life Sciences

Academic Background & Achievements

2006-2010 Bachelor: Wuhan University, Chemistry
2010-2015 PhD: Peking University, Chemical Biology

Work Experience

2015-2018 Postdoctoral Researcher: Scripps Research Institute, Chemistry and Molecular Pharmacology
2019-present Professor: Nanjing University, School of Chemistry and Chemical Engineering
2019-present Principal Investigator: Nanjing University, Institute of Chemistry and Biomedical Innovation

Awards

2022: Member of the National Huang Danian-style Faculty Team
2020: National Overseas High-Level Young Talent
2020: Second Prize of National Natural Science Award (Fourth Contributor)
2019: Jiangsu Distinguished Professor
2019: First Prize of Ministry of Education Natural Science Award (Fourth Contributor)

Areas of Focus	Chemical Immunology Antibody Modification Chemistry T Cell Adoptive Immunotherapy Disease Immune Microenvironment Decoding
Publications	Combining cisplatin and a STING agonist into one molecule for cancer metalloimmunotherapy, Zhang S, Song D, Yu W, Li J, Wang X, Li Y, Zhao Z, Xue Q, Zhao J, Li J, Guo Z, 2023 Chemoenzymatic Measurement of LacNAc in Single-Cell Multiomics Reveals It as a Cell-Surface Indicator of Glycolytic Activity of CD8+ T Cells, Yu W, Zhao X, Jalloh A, Li Y, Zhao Y, Dinner B, Yang Y, Ouyang S, Tian T, Zhao Z, Yang R, Chen M, Lauvau G, Guo Z, Wu P, Li J, 2023 Trimming Crystallizable Fragment (Fc) Glycans Enables the Direct Enzymatic Transfer of Biomacromolecules to Antibodies as Therapeutics, Yang Y, Song Z, Tian T, Zhao Z, Chen J, Hu J, Jiang X, Yang G, Xue Q, Zhao X, Sha W, Yang Y, Li J, 2023 Ru(bpy)32+-Enabled Cell-Surface Photocatalytic Proximity Labeling toward More Efficient Capture of Physically Interacting Cells, Qiu S, Li W, Deng T, Bi A, Yang Y, Jiang X, Li J, 2023 Identification of Styryl Sulfonyl Fluoride as a Near-Perfect Michael Acceptor for Diversified Protein Bioconjugations, Wu Q, Xue Q, Li J, Zheng Q, Li W, Sun S, Sha W, Yang Y, Yang Y, Li J, 2023 Improved ClickTags enable live-cell barcoding for highly multiplexed single cell sequencing, Zhao X, Sun S, Yu W, Zhu W, Zhao Z, Zhou Y, Ding X, Fang N, Yang R, Li J, 2022 Use of intercellular proximity labeling to quantify and decipher cell-cell interactions directed by diversified molecular pairs, Qiu S, Zhao Z, Wu M, Xue Q, Yang Y, Ouyang S, Li W, Zhong L, Wang W, Yang R, Wu P, Li J, 2022 Antigen-specific T cell detection via photocatalytic proximity cell labeling (PhoXCELL), Liu H, Luo H, Xue Q, Qin S, Qiu S, Liu S, Lin J, Li J, Chen P, 2022 Detecting tumor antigen-specific T cells via interaction-dependent fucosyl-biotinylation, Liu Z, Li J, Chen M, Wu M, Shi Y, Li W, Teijaro J, Wu P, 2020 Metal-mediated immune regulations and interventions: prospects of the emerging field of metalloimmunology, Li J, Zheng P, Zhao J, Chen P, Guo Z, 2019 A single-step chemoenzymatic reaction for the construction of antibody−cell conjugates, Li J, Chen M, Liu Z, Zhang L, Felding BH, Moremen KW, Lauvau G., Abadier M, Ley K, Wu P, 2018 SuFEx click chemistry enabled late-stage drug functionalization, Liu ZL, Li J, Li SH, Li GC, Sharpless KB, Wu P, 2018 Development and application of bond cleavage reactions in bioorthogonal chemistry, Li J, Chen P, 2016 Bioorthogonal chemical activation of kinases in living systems, Zhang G, Li J, Xie R, Fan X, Liu Y, Zheng S, Ge Y, Chen P, 2016 Chemical remodeling of cell-surface sialic acids through a Palladium-triggered bioorthogonal elimination reaction, Wang J, Cheng B, Li J, Zhang Z, Hong W, Chen X, Chen P, 2015 Palladium-triggered deprotection chemistry for protein activation in living cells, Li J, Yu J, Zhao J, Wang J, Zheng S, Lin S, Chen L, Yang M, Jia S, Zhang X, Chen P, 2014 Diels–Alder reaction-triggered bioorthogonal protein decaging in living cells, Li J, Jia S, Chen P, 2014 Transition metal mediated biocompatible protein chemistry in living cells, Yang M, Li J, Chen P, 2014 Ligand-free palladium-mediated site-specific protein labeling inside gram-negative bacterial pathogens, Li J, Lin S, Wang J, Jia S, Yang M, Hao Z, Zhang X, Chen P, 2013

Areas of Focus

Chemical Immunology
Antibody Modification Chemistry
T Cell Adoptive Immunotherapy
Disease Immune Microenvironment Decoding

Publications

Combining cisplatin and a STING agonist into one molecule for cancer metalloimmunotherapy, Zhang S, Song D, Yu W, Li J, Wang X, Li Y, Zhao Z, Xue Q, Zhao J, Li J, Guo Z, 2023
Chemoenzymatic Measurement of LacNAc in Single-Cell Multiomics Reveals It as a Cell-Surface Indicator of Glycolytic Activity of CD8+ T Cells, Yu W, Zhao X, Jalloh A, Li Y, Zhao Y, Dinner B, Yang Y, Ouyang S, Tian T, Zhao Z, Yang R, Chen M, Lauvau G, Guo Z, Wu P, Li J, 2023
Trimming Crystallizable Fragment (Fc) Glycans Enables the Direct Enzymatic Transfer of Biomacromolecules to Antibodies as Therapeutics, Yang Y, Song Z, Tian T, Zhao Z, Chen J, Hu J, Jiang X, Yang G, Xue Q, Zhao X, Sha W, Yang Y, Li J, 2023
Ru(bpy)32+-Enabled Cell-Surface Photocatalytic Proximity Labeling toward More Efficient Capture of Physically Interacting Cells, Qiu S, Li W, Deng T, Bi A, Yang Y, Jiang X, Li J, 2023
Identification of Styryl Sulfonyl Fluoride as a Near-Perfect Michael Acceptor for Diversified Protein Bioconjugations, Wu Q, Xue Q, Li J, Zheng Q, Li W, Sun S, Sha W, Yang Y, Yang Y, Li J, 2023
Improved ClickTags enable live-cell barcoding for highly multiplexed single cell sequencing, Zhao X, Sun S, Yu W, Zhu W, Zhao Z, Zhou Y, Ding X, Fang N, Yang R, Li J, 2022
Use of intercellular proximity labeling to quantify and decipher cell-cell interactions directed by diversified molecular pairs, Qiu S, Zhao Z, Wu M, Xue Q, Yang Y, Ouyang S, Li W, Zhong L, Wang W, Yang R, Wu P, Li J, 2022
Antigen-specific T cell detection via photocatalytic proximity cell labeling (PhoXCELL), Liu H, Luo H, Xue Q, Qin S, Qiu S, Liu S, Lin J, Li J, Chen P, 2022
Detecting tumor antigen-specific T cells via interaction-dependent fucosyl-biotinylation, Liu Z, Li J, Chen M, Wu M, Shi Y, Li W, Teijaro J, Wu P, 2020
Metal-mediated immune regulations and interventions: prospects of the emerging field of metalloimmunology, Li J, Zheng P, Zhao J, Chen P, Guo Z, 2019
A single-step chemoenzymatic reaction for the construction of antibody−cell conjugates, Li J, Chen M, Liu Z, Zhang L, Felding BH, Moremen KW, Lauvau G., Abadier M, Ley K, Wu P, 2018
SuFEx click chemistry enabled late-stage drug functionalization, Liu ZL, Li J, Li SH, Li GC, Sharpless KB, Wu P, 2018
Development and application of bond cleavage reactions in bioorthogonal chemistry, Li J, Chen P, 2016
Bioorthogonal chemical activation of kinases in living systems, Zhang G, Li J, Xie R, Fan X, Liu Y, Zheng S, Ge Y, Chen P, 2016
Chemical remodeling of cell-surface sialic acids through a Palladium-triggered bioorthogonal elimination reaction, Wang J, Cheng B, Li J, Zhang Z, Hong W, Chen X, Chen P, 2015
Palladium-triggered deprotection chemistry for protein activation in living cells, Li J, Yu J, Zhao J, Wang J, Zheng S, Lin S, Chen L, Yang M, Jia S, Zhang X, Chen P, 2014
Diels–Alder reaction-triggered bioorthogonal protein decaging in living cells, Li J, Jia S, Chen P, 2014
Transition metal mediated biocompatible protein chemistry in living cells, Yang M, Li J, Chen P, 2014
Ligand-free palladium-mediated site-specific protein labeling inside gram-negative bacterial pathogens, Li J, Lin S, Wang J, Jia S, Yang M, Hao Z, Zhang X, Chen P, 2013

Immunology Chemistry Antibody Modification T Cells Therapy Immune Microenvironment Disease Decoding

Gao Feng - University of Chinese Academy of Sciences

Feng Wang - University of Chinese Academy of Sciences

Xiao Haixia - University of Chinese Academy of Sciences

View All

Personal Information

Academic Information

Research

Contact us

No account yet?

Personal Information

Academic Information

Research

Contact us