2009-09 to 2014-06 Ph.D. in Science: University of Chinese Academy of Sciences
2005-09 to 2009-06 Bachelor's in Science: Sichuan University
2014-11 to Present - Institute of Biophysics, Chinese Academy of Sciences - Researcher
2014-07 to 2014-10 - Institute of Biophysics, Chinese Academy of Sciences - Associate Researcher
2009-09 to 2014-06 - University of Chinese Academy of Sciences - Ph.D. Student
2005-09 to 2009-06 - Sichuan University - Bachelor's Student
Young Top-notch Talent of the Ten Thousand Talents Program (2019): Ministry-level
Top Ten Scientific Advances in China (2019): Ministry-level
Top Ten Advances in Life Sciences in China (2018): Ministry-level
First Youth Support Project of the China Association for Science and Technology (2015): Ministry-level
Fourth Bei Shizhang Young Biophysicist Award (2015): Ministry-level
Research
Virology Structural Biology
Structural and molecular basis for foot-and-mouth disease virus neutralization by two potent protective antibodies, Xiangxi Wang, 2022
Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron, Xiangxi Wang, 2022
Memory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants, Xiangxi Wang, 2022
A proof of concept for neutralizing antibody-guided vaccine design against SARS-CoV-2, Xiangxi Wang, 2021
SARS-CoV-2 spike protein interacts with and activates TLR4, Xiangxi Wang, 2021
Structural basis for neutralization of an anicteric hepatitis associated echovirus by a potent neutralizing antibody, Xiangxi Wang, 2021
Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms, Xiangxi Wang, 2021
Structure-based development of human antibody cocktails against SARS-CoV-2, Xiangxi Wang, 2021
Nanometer-resolution in situ structure of the SARS-CoV-2 postfusion spike protein, Xiangxi Wang, 2021
Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18-59 years: a randomised, double-blind, placebo-controlled, phase 1/2 clinical trial, Xiangxi Wang, 2021
Omicron escapes the majority of existing SARS-CoV-2 neutralizing antibodies, Xiangxi Wang, 2021
Rational development of a human antibody cocktail that deploys multiple functions to confer Pan-SARS-CoVs protection, Xiangxi Wang, 2021
Double lock of a potent human therapeutic monoclonal antibody against SARS-CoV-2, Xiangxi Wang, 2021
Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2, Xiangxi Wang, 2021
Induction of alarmin S100A8/A9 mediates activation of aberrant neutrophils in the pathogenesis of COVID-19, Xiangxi Wang, 2021
Hand-foot-and-mouth disease virus receptor KREMEN1 binds the canyon of Coxsackie Virus A10, Xiangxi Wang, 2020
Structures of the portal vertex reveal essential protein-protein interactions for Herpesvirus assembly and maturation, Xiangxi Wang, 2020
Serotype specific epitopes identified by neutralizing antibodies underpin immunogenic differences in Enterovirus B, Xiangxi Wang, 2020
Structures of Echovirus 30 in complex with its receptors inform a rational prediction for enterovirus receptor usage, Xiangxi Wang, 2020
Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody, Xiangxi Wang, 2020
Development of an inactivated vaccine candidate for SARS-CoV-2, Xiangxi Wang, 2020
Design, Synthesis, and Evaluation of Novel Enterovirus 71 Inhibitors as Therapeutic Drug Leads for the Treatment of Human Hand, Foot, and Mouth Disease, Xiangxi Wang, 2020
Architecture of the herpesvirus genome-packaging complex and implications for DNA translocation, Xiangxi Wang, 2020
Structural basis for neutralization of hepatitis A virus informs a rational design of highly potent inhibitors, Xiangxi Wang, 2019
Architecture of African swine fever virus and implications for viral assembly, Xiangxi Wang, 2019
Neutralization Mechanisms of Two Highly Potent Antibodies against Human Enterovirus 71, Xiangxi Wang, 2018
Structural basis for neutralization of Japanese encephalitis virus by two potent therapeutic antibodies, Xiangxi Wang, 2018
Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component, Xiangxi Wang, 2018
Cryo-EM structure of Type III-A CRISPR effector complex, Xiangxi Wang, 2018
Cryo-EM structure of a herpesvirus capsid at 3.1 angstrom, Xiangxi Wang, 2018
Structures of Coxsackievirus A10 unveil the molecular mechanisms of receptor binding and viral uncoating, Xiangxi Wang, 2018
Potent neutralization of hepatitis A virus reveals a receptor mimic mechanism and the receptor recognition site, Xiangxi Wang, 2017
Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability, Xiangxi Wang, 2017
Structure of human Aichi virus and implications for receptor binding, Xiangxi Wang, 2016
Structure of Ljungan virus reveals a novel mechanism for picornavirus genome packaging, Xiangxi Wang, 2015
Hepatitis A virus and the origins of picornaviruses, Xiangxi Wang, 2015
More powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules, Xiangxi Wang, 2014
Molecular mechanism of SCARB2-mediated attachment and uncoating of EV71, Xiangxi Wang, 2014
Picornavirus uncoating intermediate captured in atomic detail, Xiangxi Wang, 2013
An open conformation determined by a structural switch for 2A protease from coxsackievirus A16, Xiangxi Wang, 2013
A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71, Xiangxi Wang, 2012
Area of Focus
Immunology | B-Cells | Antibodies | Somatic Hypermutation | Pathogens | Autoimmunity | Gut Microbiome | Host Interactions | Vaccines | Traditional Chinese Medicine
