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Yuezhou Chen
Life Science
Peking University
Beijing
Language: English, Chinese
Immunology
B-Cells
Antibodies
Somatic Hypermutation
Pathogens
Autoimmunity
Gut Microbiome
Host Interactions
Vaccines
Traditional Chinese Medicine
Areas of Focus
- B-cell mediated immunology
- Infectious diseases and vaccine-induced immune responses
- Gut microbiome and host interactions
- Traditional Chinese medicine and immune system regulation
Work Experience
- 2014-2020 Postdoctoral Researcher, Harvard Medical School/Brigham Women's Hospital
- 2020-2022 Lecturer, Harvard Medical School
- 2022-present Researcher, Peking University
- 2022-present Researcher, Peking-Tsinghua Center for Life Sciences
Academic Background & Achievements
- 2000-2004 Bachelor of Biological Sciences, Sichuan University
- 2004-2009 PhD in Cell Biology, Peking University
- 2009-2014 PhD in Medicine, China Academy of Chinese Medical Sciences
Publications
- Immune recall improves antibody durability and breadth to SARS-CoV-2 variants, Chen Y, et al., 2022
- Quick COVID-19 Healers Sustain Anti-SARS-CoV-2 Antibody Production, Chen Y, et al., 2020
- Microbial symbionts regulate the primary Ig repertoire, Chen Y, et al., 2018
- Antitumor effect of traditional Chinese herbal medicines against lung cancer, Chen Y, et al., 2014
- Anti-HBV effect of individual traditional Chinese herbal medicine in vitro and in vivo: an analytic review, Chen Y, et al., 2013
- Cullin Mediates Degradation of RhoA through Evolutionarily Conserved BTB Adaptors to Control Actin Cytoskeleton Structure and Cell Movement, Chen Y, et al., 2009
- SARS-CoV-2 epitope–specific CD4+ memory T cell responses across COVID-19 disease severity and antibody durability, Nelson R, Chen Y, et al., 2022
- Antibodies induced by ancestral SARS-CoV-2 strain that cross-neutralize variants from Alpha to Omicron BA. 1, Windsor I, Chen Y, et al., 2022
- Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike, Tong P, Chen Y, et al., 2021
- Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity, Shrock E, Chen Y, et al., 2020
- DNA vaccine protection against SARS-CoV-2 in rhesus macaques, Yu J, Chen Y, et al., 2020
- Lactobacillus-deficient cervicovaginal bacterial communities are associated with increased HIV acquisition in young South African women, Gosmann C, Chen Y, et al., 2017
- Primary immunoglobulin repertoire development: time and space matter, Granato A, Chen Y, et al., 2015
Awards
- 2024 Benyuan Fund Young PI Research Grant
- 2023 Yifang Scholar
- 2021 Best Presentation Award, Brigham Women's Hospital Allergy and Clinical Immunology Department Annual Meeting
- 2019-2021 Ruth L. Kirschstein National Research Service Award, NIH
- 2014 First Prize, Perfect (China) Scholarship for Scientific Innovation, China Academy of Chinese Medical Sciences
- 2008 Outstanding Graduate Student Award, Beijing Institute of Life Sciences
